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KIF6 (kinesin family member 6)

Identity

Alias_namesC6orf102
chromosome 6 open reading frame 102
Alias_symbol (synonym)dJ1043E3.1
MGC33317
dJ137F1.4
dJ188D3.1
DKFZp451I2418
Other alias
HGNC (Hugo) KIF6
LocusID (NCBI) 221458
Atlas_Id 52959
Location 6p21.2  [Link to chromosome band 6p21]
Location_base_pair Starts at 39329990 and ends at 39725423 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
KCNK17 (6p21.2) / KIF6 (6p21.2)KCNK5 (6p21.2) / KIF6 (6p21.2)VEGFA (6p21.1) / KIF6 (6p21.2)
KCNK5 6p21.2 / KIF6 6p21.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(6;6)(p21;p21) KCNK17/KIF6


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  KCNK5/KIF6 (6p21)


External links

Nomenclature
HGNC (Hugo)KIF6   21202
Cards
Entrez_Gene (NCBI)KIF6  221458  kinesin family member 6
AliasesC6orf102; dJ1043E3.1; dJ137F1.4; dJ188D3.1
GeneCards (Weizmann)KIF6
Ensembl hg19 (Hinxton)ENSG00000164627 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000164627 [Gene_View]  ENSG00000164627 [Sequence]  chr6:39329990-39725423 [Contig_View]  KIF6 [Vega]
ICGC DataPortalENSG00000164627
TCGA cBioPortalKIF6
AceView (NCBI)KIF6
Genatlas (Paris)KIF6
WikiGenes221458
SOURCE (Princeton)KIF6
Genetics Home Reference (NIH)KIF6
Genomic and cartography
GoldenPath hg38 (UCSC)KIF6  -     chr6:39329990-39725423 -  6p21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KIF6  -     6p21.2   [Description]    (hg19-Feb_2009)
EnsemblKIF6 - 6p21.2 [CytoView hg19]  KIF6 - 6p21.2 [CytoView hg38]
Mapping of homologs : NCBIKIF6 [Mapview hg19]  KIF6 [Mapview hg38]
OMIM613919   
Gene and transcription
Genbank (Entrez)AK097521 AK123217 AK131471 AL832634 BC022074
RefSeq transcript (Entrez)NM_001289020 NM_001289021 NM_001289024 NM_001351503 NM_001351566 NM_145027
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KIF6
Cluster EST : UnigeneHs.703192 [ NCBI ]
CGAP (NCI)Hs.703192
Alternative Splicing GalleryENSG00000164627
Gene ExpressionKIF6 [ NCBI-GEO ]   KIF6 [ EBI - ARRAY_EXPRESS ]   KIF6 [ SEEK ]   KIF6 [ MEM ]
Gene Expression Viewer (FireBrowse)KIF6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)221458
GTEX Portal (Tissue expression)KIF6
Human Protein AtlasENSG00000164627-KIF6 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6ZMV9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6ZMV9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6ZMV9
Splice isoforms : SwissVarQ6ZMV9
PhosPhoSitePlusQ6ZMV9
Domaine pattern : Prosite (Expaxy)KINESIN_MOTOR_1 (PS00411)    KINESIN_MOTOR_2 (PS50067)   
Domains : Interpro (EBI)Kinesin-like_fam    Kinesin_motor_CS    Kinesin_motor_dom    Kinesin_motor_dom_sf    P-loop_NTPase   
Domain families : Pfam (Sanger)Kinesin (PF00225)   
Domain families : Pfam (NCBI)pfam00225   
Domain families : Smart (EMBL)KISc (SM00129)  
Conserved Domain (NCBI)KIF6
DMDM Disease mutations221458
Blocks (Seattle)KIF6
SuperfamilyQ6ZMV9
Human Protein Atlas [tissue]ENSG00000164627-KIF6 [tissue]
Peptide AtlasQ6ZMV9
HPRD10786
IPIIPI00414252   IPI00607613   IPI00446729   IPI00654807   IPI00607636   IPI00552053   IPI01018757   IPI01019013   IPI01019097   IPI00789970   
Protein Interaction databases
DIP (DOE-UCLA)Q6ZMV9
IntAct (EBI)Q6ZMV9
FunCoupENSG00000164627
BioGRIDKIF6
STRING (EMBL)KIF6
ZODIACKIF6
Ontologies - Pathways
QuickGOQ6ZMV9
Ontology : AmiGOmale germ cell nucleus  microtubule motor activity  protein binding  ATP binding  cytoplasm  kinesin complex  microtubule  microtubule-based movement  microtubule binding  ATPase activity  
Ontology : EGO-EBImale germ cell nucleus  microtubule motor activity  protein binding  ATP binding  cytoplasm  kinesin complex  microtubule  microtubule-based movement  microtubule binding  ATPase activity  
NDEx NetworkKIF6
Atlas of Cancer Signalling NetworkKIF6
Wikipedia pathwaysKIF6
Orthology - Evolution
OrthoDB221458
GeneTree (enSembl)ENSG00000164627
Phylogenetic Trees/Animal Genes : TreeFamKIF6
HOVERGENQ6ZMV9
HOGENOMQ6ZMV9
Homologs : HomoloGeneKIF6
Homology/Alignments : Family Browser (UCSC)KIF6
Gene fusions - Rearrangements
Fusion : MitelmanKCNK17/KIF6 [6p21.2/6p21.2]  [t(6;6)(p21;p21)]  
Fusion : MitelmanKCNK5/KIF6 [6p21.2/6p21.2]  [t(6;6)(p21;p21)]  
Fusion PortalKCNK5 6p21.2 KIF6 6p21.2 LUSC
Fusion : QuiverKIF6
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKIF6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KIF6
dbVarKIF6
ClinVarKIF6
1000_GenomesKIF6 
Exome Variant ServerKIF6
ExAC (Exome Aggregation Consortium)ENSG00000164627
GNOMAD BrowserENSG00000164627
Varsome BrowserKIF6
Genetic variants : HAPMAP221458
Genomic Variants (DGV)KIF6 [DGVbeta]
DECIPHERKIF6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKIF6 
Mutations
ICGC Data PortalKIF6 
TCGA Data PortalKIF6 
Broad Tumor PortalKIF6
OASIS PortalKIF6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKIF6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKIF6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KIF6
DgiDB (Drug Gene Interaction Database)KIF6
DoCM (Curated mutations)KIF6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KIF6 (select a term)
intoGenKIF6
Cancer3DKIF6(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613919   
Orphanet
DisGeNETKIF6
MedgenKIF6
Genetic Testing Registry KIF6
NextProtQ6ZMV9 [Medical]
TSGene221458
GENETestsKIF6
Target ValidationKIF6
Huge Navigator KIF6 [HugePedia]
snp3D : Map Gene to Disease221458
BioCentury BCIQKIF6
ClinGenKIF6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD221458
Chemical/Pharm GKB GenePA134920075
Clinical trialKIF6
Miscellaneous
canSAR (ICR)KIF6 (select the gene name)
Probes
Litterature
PubMed53 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKIF6
EVEXKIF6
GoPubMedKIF6
iHOPKIF6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:15:04 CET 2018

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