Atlas of Genetics and Cytogenetics in Oncology and Haematology


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KIFAP3 (kinesin associated protein 3)

Identity

Alias_nameskinesin-associated protein 3
Alias_symbol (synonym)SMAP
KAP3
FLA3
KAP-1
Other aliasKAP-3
Smg-GDS
dJ190I16.1
HGNC (Hugo) KIFAP3
LocusID (NCBI) 22920
Atlas_Id 56347
Location 1q24.2  [Link to chromosome band 1q24]
Location_base_pair Starts at 169921329 and ends at 170074738 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DDIAS (11q14.1) / KIFAP3 (1q24.2)KIFAP3 (1q24.2) / DUSP27 (1q24.1)RREB1 (6p24.3) / KIFAP3 (1q24.2)
XPR1 (1q25.3) / KIFAP3 (1q24.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KIFAP3   17060
Cards
Entrez_Gene (NCBI)KIFAP3  22920  kinesin associated protein 3
AliasesFLA3; KAP-1; KAP-3; KAP3; 
SMAP; Smg-GDS; dJ190I16.1
GeneCards (Weizmann)KIFAP3
Ensembl hg19 (Hinxton)ENSG00000075945 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000075945 [Gene_View]  chr1:169921329-170074738 [Contig_View]  KIFAP3 [Vega]
ICGC DataPortalENSG00000075945
TCGA cBioPortalKIFAP3
AceView (NCBI)KIFAP3
Genatlas (Paris)KIFAP3
WikiGenes22920
SOURCE (Princeton)KIFAP3
Genetics Home Reference (NIH)KIFAP3
Genomic and cartography
GoldenPath hg38 (UCSC)KIFAP3  -     chr1:169921329-170074738 -  1q24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KIFAP3  -     1q24.2   [Description]    (hg19-Feb_2009)
EnsemblKIFAP3 - 1q24.2 [CytoView hg19]  KIFAP3 - 1q24.2 [CytoView hg38]
Mapping of homologs : NCBIKIFAP3 [Mapview hg19]  KIFAP3 [Mapview hg38]
OMIM601836   
Gene and transcription
Genbank (Entrez)AI085654 AK026471 AK122897 AK297368 AK301912
RefSeq transcript (Entrez)NM_001204514 NM_001204516 NM_001204517 NM_014970
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KIFAP3
Cluster EST : UnigeneHs.433442 [ NCBI ]
CGAP (NCI)Hs.433442
Alternative Splicing GalleryENSG00000075945
Gene ExpressionKIFAP3 [ NCBI-GEO ]   KIFAP3 [ EBI - ARRAY_EXPRESS ]   KIFAP3 [ SEEK ]   KIFAP3 [ MEM ]
Gene Expression Viewer (FireBrowse)KIFAP3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)22920
GTEX Portal (Tissue expression)KIFAP3
Human Protein AtlasENSG00000075945-KIFAP3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ92845   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ92845  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ92845
Splice isoforms : SwissVarQ92845
PhosPhoSitePlusQ92845
Domaine pattern : Prosite (Expaxy)ARM_REPEAT (PS50176)   
Domains : Interpro (EBI)ARM-like    ARM-type_fold    Armadillo    KAP3   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)ARM (SM00185)  
Conserved Domain (NCBI)KIFAP3
DMDM Disease mutations22920
Blocks (Seattle)KIFAP3
SuperfamilyQ92845
Human Protein Atlas [tissue]ENSG00000075945-KIFAP3 [tissue]
Peptide AtlasQ92845
HPRD03499
IPIIPI00647465   IPI01011855   IPI01009014   IPI00515034   IPI00642545   
Protein Interaction databases
DIP (DOE-UCLA)Q92845
IntAct (EBI)Q92845
FunCoupENSG00000075945
BioGRIDKIFAP3
STRING (EMBL)KIFAP3
ZODIACKIFAP3
Ontologies - Pathways
QuickGOQ92845
Ontology : AmiGOcondensed nuclear chromosome  protein binding  endoplasmic reticulum  Golgi apparatus  centrosome  cytosol  spindle microtubule  cilium  axoneme  protein complex assembly  retrograde vesicle-mediated transport, Golgi to ER  microtubule-based process  microtubule-based movement  signal transduction  negative regulation of cell proliferation  microtubule cytoskeleton  kinesin II complex  kinesin II complex  antigen processing and presentation of exogenous peptide antigen via MHC class II  kinesin binding  intraciliary transport particle  photoreceptor connecting cilium  intraciliary transport involved in cilium assembly  ciliary basal body  negative regulation of apoptotic process  positive regulation of calcium-dependent cell-cell adhesion  extracellular exosome  plus-end-directed vesicle transport along microtubule  ciliary tip  periciliary membrane compartment  
Ontology : EGO-EBIcondensed nuclear chromosome  protein binding  endoplasmic reticulum  Golgi apparatus  centrosome  cytosol  spindle microtubule  cilium  axoneme  protein complex assembly  retrograde vesicle-mediated transport, Golgi to ER  microtubule-based process  microtubule-based movement  signal transduction  negative regulation of cell proliferation  microtubule cytoskeleton  kinesin II complex  kinesin II complex  antigen processing and presentation of exogenous peptide antigen via MHC class II  kinesin binding  intraciliary transport particle  photoreceptor connecting cilium  intraciliary transport involved in cilium assembly  ciliary basal body  negative regulation of apoptotic process  positive regulation of calcium-dependent cell-cell adhesion  extracellular exosome  plus-end-directed vesicle transport along microtubule  ciliary tip  periciliary membrane compartment  
NDEx NetworkKIFAP3
Atlas of Cancer Signalling NetworkKIFAP3
Wikipedia pathwaysKIFAP3
Orthology - Evolution
OrthoDB22920
GeneTree (enSembl)ENSG00000075945
Phylogenetic Trees/Animal Genes : TreeFamKIFAP3
HOVERGENQ92845
HOGENOMQ92845
Homologs : HomoloGeneKIFAP3
Homology/Alignments : Family Browser (UCSC)KIFAP3
Gene fusions - Rearrangements
Tumor Fusion PortalKIFAP3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKIFAP3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KIFAP3
dbVarKIFAP3
ClinVarKIFAP3
1000_GenomesKIFAP3 
Exome Variant ServerKIFAP3
ExAC (Exome Aggregation Consortium)ENSG00000075945
GNOMAD BrowserENSG00000075945
Genetic variants : HAPMAP22920
Genomic Variants (DGV)KIFAP3 [DGVbeta]
DECIPHERKIFAP3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKIFAP3 
Mutations
ICGC Data PortalKIFAP3 
TCGA Data PortalKIFAP3 
Broad Tumor PortalKIFAP3
OASIS PortalKIFAP3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKIFAP3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKIFAP3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KIFAP3
DgiDB (Drug Gene Interaction Database)KIFAP3
DoCM (Curated mutations)KIFAP3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KIFAP3 (select a term)
intoGenKIFAP3
Cancer3DKIFAP3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601836   
Orphanet
DisGeNETKIFAP3
MedgenKIFAP3
Genetic Testing Registry KIFAP3
NextProtQ92845 [Medical]
TSGene22920
GENETestsKIFAP3
Target ValidationKIFAP3
Huge Navigator KIFAP3 [HugePedia]
snp3D : Map Gene to Disease22920
BioCentury BCIQKIFAP3
ClinGenKIFAP3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD22920
Chemical/Pharm GKB GenePA30111
Clinical trialKIFAP3
Miscellaneous
canSAR (ICR)KIFAP3 (select the gene name)
Probes
Litterature
PubMed40 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKIFAP3
EVEXKIFAP3
GoPubMedKIFAP3
iHOPKIFAP3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:18:57 CET 2017

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