KIFC3 (kinesin family member C3)

2010-01-01  

Identity

HGNC
LOCATION
16q21
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 3801
MIM: 604535
HGNC: 6326
Ensembl: ENSG00000140859

Variants:

dbSNP: 3801
ClinVar: 3801
TCGA: ENSG00000140859
COSMIC: KIFC3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000140859ENST00000379655Q9BVG8
ENSG00000140859ENST00000421376Q9BVG8
ENSG00000140859ENST00000445690Q9BVG8
ENSG00000140859ENST00000465878Q9BVG8
ENSG00000140859ENST00000540079F5H3M2
ENSG00000140859ENST00000541240Q9BVG8
ENSG00000140859ENST00000543930B7Z896
ENSG00000140859ENST00000561524H3BMZ5
ENSG00000140859ENST00000562311H3BMR0
ENSG00000140859ENST00000562503H3BMQ3
ENSG00000140859ENST00000562903Q9BVG8
ENSG00000140859ENST00000562984H3BMJ1
ENSG00000140859ENST00000563028H3BRQ1
ENSG00000140859ENST00000564136A0A0C4DGM9
ENSG00000140859ENST00000564891H3BNZ0
ENSG00000140859ENST00000565270H3BTL6
ENSG00000140859ENST00000565397H3BUC0
ENSG00000140859ENST00000565481H3BTU1
ENSG00000140859ENST00000565684H3BPE2
ENSG00000140859ENST00000566648H3BSN2
ENSG00000140859ENST00000567059H3BTE9
ENSG00000140859ENST00000569112H3BTN1
ENSG00000140859ENST00000569222H3BV47

Expression (GTEx)

0
10
20
30
40
50
60

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Protein foldingREACTOMER-HSA-391251
Chaperonin-mediated protein foldingREACTOMER-HSA-390466
Association of TriC/CCT with target proteins during biosynthesisREACTOMER-HSA-390471

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
197893442009Overexpression of kinesins mediates docetaxel resistance in breast cancer cells.49
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11
239544412013Identification of the kinesin KifC3 as a new player for positioning of peroxisomes and other organelles in mammalian cells.8
252537212014Minus end-directed motor KIFC3 suppresses E-cadherin degradation by recruiting USP47 to adherens junctions.7
314817952019The balance between KIFC3 and EG5 tetrameric kinesins controls the onset of mitotic spindle assembly.6
269545572016Alteration of Motor Protein Expression Involved in Bidirectional Transport in Peripheral Blood Mononuclear Cells of Patients with Amyotrophic Lateral Sclerosis.4
242758652014KIFC3 promotes mitotic progression and integrity of the central spindle in cytokinesis.1

Citation

Dessen P

KIFC3 (kinesin family member C3)

Atlas Genet Cytogenet Oncol Haematol. 2010-01-01

Online version: http://atlasgeneticsoncology.org/gene/51312/kifc3