Atlas of Genetics and Cytogenetics in Oncology and Haematology


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KIR2DL3 (killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3)

Identity

Alias_nameskiller cell immunoglobulin-like receptor
Alias_symbol (synonym)cl-6
nkat2
nkat2a
nkat2b
p58
CD158B2
Other aliasCD158b
GL183
KIR-023GB
KIR-K7b
KIR-K7c
KIR2DS5
KIRCL23
NKAT
NKAT2
NKAT2A
NKAT2B
HGNC (Hugo) KIR2DL3
LocusID (NCBI) 3804
Atlas_Id 43615
Location 19q13.42  [Link to chromosome band 19q13]
Location_base_pair Starts at 55249974 and ends at 55264504 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KIR2DL3   6331
Cards
Entrez_Gene (NCBI)KIR2DL3  3804  killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3
AliasesCD158B2; CD158b; GL183; KIR-023GB; 
KIR-K7b; KIR-K7c; KIR2DS5; KIRCL23; NKAT; NKAT2; NKAT2A; NKAT2B; p58
GeneCards (Weizmann)KIR2DL3
Ensembl hg19 (Hinxton)ENSG00000243772 [Gene_View]  chr19:55249974-55264504 [Contig_View]  KIR2DL3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000243772 [Gene_View]  chr19:55249974-55264504 [Contig_View]  KIR2DL3 [Vega]
ICGC DataPortalENSG00000243772
TCGA cBioPortalKIR2DL3
AceView (NCBI)KIR2DL3
Genatlas (Paris)KIR2DL3
WikiGenes3804
SOURCE (Princeton)KIR2DL3
Genetics Home Reference (NIH)KIR2DL3
Genomic and cartography
GoldenPath hg19 (UCSC)KIR2DL3  -     chr19:55249974-55264504 +  19q13.42   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)KIR2DL3  -     19q13.42   [Description]    (hg38-Dec_2013)
EnsemblKIR2DL3 - 19q13.42 [CytoView hg19]  KIR2DL3 - 19q13.42 [CytoView hg38]
Mapping of homologs : NCBIKIR2DL3 [Mapview hg19]  KIR2DL3 [Mapview hg38]
OMIM604938   
Gene and transcription
Genbank (Entrez)AF022048 AF135556 AF135566 AF135567 AF285435
RefSeq transcript (Entrez)NM_014511 NM_015868
RefSeq genomic (Entrez)NC_000019 NC_018930 NT_011109 NT_187637 NT_187639 NT_187641 NT_187643 NT_187645 NT_187669 NT_187671 NT_187672 NT_187673 NT_187674 NT_187676 NT_187683 NT_187684 NT_187685 NT_187687 NT_187693 NW_003571054 NW_003571059 NW_003571060 NW_004929415
Consensus coding sequences : CCDS (NCBI)KIR2DL3
Cluster EST : UnigeneHs.731378 [ NCBI ]
CGAP (NCI)Hs.731378
Alternative Splicing GalleryENSG00000243772
Gene ExpressionKIR2DL3 [ NCBI-GEO ]   KIR2DL3 [ EBI - ARRAY_EXPRESS ]   KIR2DL3 [ SEEK ]   KIR2DL3 [ MEM ]
Gene Expression Viewer (FireBrowse)KIR2DL3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3804
GTEX Portal (Tissue expression)KIR2DL3
Protein : pattern, domain, 3D structure
UniProt/SwissProtP43628   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP43628  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP43628
Splice isoforms : SwissVarP43628
PhosPhoSitePlusP43628
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig_sub    Immunoglobulin   
Domain families : Pfam (Sanger)ig (PF00047)   
Domain families : Pfam (NCBI)pfam00047   
Domain families : Smart (EMBL)IG (SM00409)  
Conserved Domain (NCBI)KIR2DL3
DMDM Disease mutations3804
Blocks (Seattle)KIR2DL3
PDB (SRS)1B6U   
PDB (PDBSum)1B6U   
PDB (IMB)1B6U   
PDB (RSDB)1B6U   
Structural Biology KnowledgeBase1B6U   
SCOP (Structural Classification of Proteins)1B6U   
CATH (Classification of proteins structures)1B6U   
SuperfamilyP43628
Human Protein AtlasENSG00000243772
Peptide AtlasP43628
HPRD10383
IPIIPI00184932   IPI00956480   IPI00930386   IPI00956553   IPI00956462   IPI00956728   IPI00956592   IPI00956338   IPI00956526   IPI00930159   IPI00956662   IPI00984178   IPI00930611   IPI00019885   IPI00930730   IPI00956218   IPI00555807   IPI00384702   IPI00429677   IPI00910926   IPI00383768   IPI00940219   IPI00872507   
Protein Interaction databases
DIP (DOE-UCLA)P43628
IntAct (EBI)P43628
FunCoupENSG00000243772
BioGRIDKIR2DL3
STRING (EMBL)KIR2DL3
ZODIACKIR2DL3
Ontologies - Pathways
QuickGOP43628
Ontology : AmiGOantigen binding  receptor activity  protein binding  plasma membrane  integral component of plasma membrane  immune response  integral component of membrane  regulation of immune response  
Ontology : EGO-EBIantigen binding  receptor activity  protein binding  plasma membrane  integral component of plasma membrane  immune response  integral component of membrane  regulation of immune response  
Pathways : KEGGAntigen processing and presentation    Natural killer cell mediated cytotoxicity    Graft-versus-host disease   
NDEx NetworkKIR2DL3
Atlas of Cancer Signalling NetworkKIR2DL3
Wikipedia pathwaysKIR2DL3
Orthology - Evolution
OrthoDB3804
GeneTree (enSembl)ENSG00000243772
Phylogenetic Trees/Animal Genes : TreeFamKIR2DL3
HOVERGENP43628
HOGENOMP43628
Homologs : HomoloGeneKIR2DL3
Homology/Alignments : Family Browser (UCSC)KIR2DL3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKIR2DL3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KIR2DL3
dbVarKIR2DL3
ClinVarKIR2DL3
1000_GenomesKIR2DL3 
Exome Variant ServerKIR2DL3
ExAC (Exome Aggregation Consortium)KIR2DL3 (select the gene name)
Genetic variants : HAPMAP3804
Genomic Variants (DGV)KIR2DL3 [DGVbeta]
DECIPHER (Syndromes)19:55249974-55264504  ENSG00000243772
CONAN: Copy Number AnalysisKIR2DL3 
Mutations
ICGC Data PortalKIR2DL3 
TCGA Data PortalKIR2DL3 
Broad Tumor PortalKIR2DL3
OASIS PortalKIR2DL3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKIR2DL3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKIR2DL3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KIR2DL3
DgiDB (Drug Gene Interaction Database)KIR2DL3
DoCM (Curated mutations)KIR2DL3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KIR2DL3 (select a term)
intoGenKIR2DL3
Cancer3DKIR2DL3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604938   
Orphanet
MedgenKIR2DL3
Genetic Testing Registry KIR2DL3
NextProtP43628 [Medical]
TSGene3804
GENETestsKIR2DL3
Huge Navigator KIR2DL3 [HugePedia]
snp3D : Map Gene to Disease3804
BioCentury BCIQKIR2DL3
ClinGenKIR2DL3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3804
Chemical/Pharm GKB GenePA30116
Clinical trialKIR2DL3
Miscellaneous
canSAR (ICR)KIR2DL3 (select the gene name)
Probes
Litterature
PubMed150 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKIR2DL3
EVEXKIR2DL3
GoPubMedKIR2DL3
iHOPKIR2DL3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 15:06:14 CEST 2017

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