Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

KIR2DL4 (killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4)

Identity

Alias_nameskiller cell immunoglobulin-like receptor
Alias_symbol (synonym)103AS
15.212
CD158D
Other aliasG9P
KIR
KIR-103AS
KIR-2DL4
KIR103
KIR103AS
HGNC (Hugo) KIR2DL4
LocusID (NCBI) 3805
Atlas_Id 55769
Location 19q13.42  [Link to chromosome band 19q13]
Location_base_pair Starts at 55315067 and ends at 55325972 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KIR2DL4   6332
Cards
Entrez_Gene (NCBI)KIR2DL4  3805  killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4
AliasesCD158D; G9P; KIR; KIR-103AS; 
KIR-2DL4; KIR103; KIR103AS
GeneCards (Weizmann)KIR2DL4
Ensembl hg19 (Hinxton)ENSG00000189013 [Gene_View]  chr19:55315067-55325972 [Contig_View]  KIR2DL4 [Vega]
Ensembl hg38 (Hinxton)ENSG00000189013 [Gene_View]  chr19:55315067-55325972 [Contig_View]  KIR2DL4 [Vega]
ICGC DataPortalENSG00000189013
TCGA cBioPortalKIR2DL4
AceView (NCBI)KIR2DL4
Genatlas (Paris)KIR2DL4
WikiGenes3805
SOURCE (Princeton)KIR2DL4
Genetics Home Reference (NIH)KIR2DL4
Genomic and cartography
GoldenPath hg19 (UCSC)KIR2DL4  -     chr19:55315067-55325972 +  19q13.42   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)KIR2DL4  -     19q13.42   [Description]    (hg38-Dec_2013)
EnsemblKIR2DL4 - 19q13.42 [CytoView hg19]  KIR2DL4 - 19q13.42 [CytoView hg38]
Mapping of homologs : NCBIKIR2DL4 [Mapview hg19]  KIR2DL4 [Mapview hg38]
OMIM604945   
Gene and transcription
Genbank (Entrez)AF002256 AF002979 AF002980 AF002981 AF002982
RefSeq transcript (Entrez)NM_001080770 NM_001080772 NM_001258383 NM_002255
RefSeq genomic (Entrez)NC_000019 NC_018930 NG_005994 NT_011109 NT_113949 NT_187636 NT_187637 NT_187638 NT_187639 NT_187640 NT_187641 NT_187642 NT_187643 NT_187644 NT_187645 NT_187668 NT_187669 NT_187670 NT_187671 NT_187672 NT_187673 NT_187674 NT_187675 NT_187676 NT_187677 NT_187683 NT_187684 NT_187685 NT_187686 NT_187687 NT_187693 NW_003571055 NW_003571060 NW_004929415
Consensus coding sequences : CCDS (NCBI)KIR2DL4
Cluster EST : UnigeneHs.743945 [ NCBI ]
CGAP (NCI)Hs.743945
Alternative Splicing GalleryENSG00000189013
Gene ExpressionKIR2DL4 [ NCBI-GEO ]   KIR2DL4 [ EBI - ARRAY_EXPRESS ]   KIR2DL4 [ SEEK ]   KIR2DL4 [ MEM ]
Gene Expression Viewer (FireBrowse)KIR2DL4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3805
GTEX Portal (Tissue expression)KIR2DL4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99706   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ99706  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ99706
Splice isoforms : SwissVarQ99706
PhosPhoSitePlusQ99706
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig_sub    Immunoglobulin   
Domain families : Pfam (Sanger)ig (PF00047)   
Domain families : Pfam (NCBI)pfam00047   
Domain families : Smart (EMBL)IG (SM00409)  
Conserved Domain (NCBI)KIR2DL4
DMDM Disease mutations3805
Blocks (Seattle)KIR2DL4
PDB (SRS)3WYR   
PDB (PDBSum)3WYR   
PDB (IMB)3WYR   
PDB (RSDB)3WYR   
Structural Biology KnowledgeBase3WYR   
SCOP (Structural Classification of Proteins)3WYR   
CATH (Classification of proteins structures)3WYR   
SuperfamilyQ99706
Human Protein AtlasENSG00000189013
Peptide AtlasQ99706
HPRD16082
IPIIPI01025846   IPI00871946   IPI00218705   IPI00218706   IPI00872526   IPI00218708   IPI00871481   IPI00936257   IPI00790647   
Protein Interaction databases
DIP (DOE-UCLA)Q99706
IntAct (EBI)Q99706
FunCoupENSG00000189013
BioGRIDKIR2DL4
STRING (EMBL)KIR2DL4
ZODIACKIR2DL4
Ontologies - Pathways
QuickGOQ99706
Ontology : AmiGOtransmembrane signaling receptor activity  protein binding  plasma membrane  integral component of plasma membrane  cellular defense response  signal transduction  membrane  regulation of immune response  
Ontology : EGO-EBItransmembrane signaling receptor activity  protein binding  plasma membrane  integral component of plasma membrane  cellular defense response  signal transduction  membrane  regulation of immune response  
Pathways : KEGGAntigen processing and presentation    Natural killer cell mediated cytotoxicity   
NDEx NetworkKIR2DL4
Atlas of Cancer Signalling NetworkKIR2DL4
Wikipedia pathwaysKIR2DL4
Orthology - Evolution
OrthoDB3805
GeneTree (enSembl)ENSG00000189013
Phylogenetic Trees/Animal Genes : TreeFamKIR2DL4
HOVERGENQ99706
HOGENOMQ99706
Homologs : HomoloGeneKIR2DL4
Homology/Alignments : Family Browser (UCSC)KIR2DL4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKIR2DL4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KIR2DL4
dbVarKIR2DL4
ClinVarKIR2DL4
1000_GenomesKIR2DL4 
Exome Variant ServerKIR2DL4
ExAC (Exome Aggregation Consortium)KIR2DL4 (select the gene name)
Genetic variants : HAPMAP3805
Genomic Variants (DGV)KIR2DL4 [DGVbeta]
DECIPHER (Syndromes)19:55315067-55325972  ENSG00000189013
CONAN: Copy Number AnalysisKIR2DL4 
Mutations
ICGC Data PortalKIR2DL4 
TCGA Data PortalKIR2DL4 
Broad Tumor PortalKIR2DL4
OASIS PortalKIR2DL4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKIR2DL4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKIR2DL4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KIR2DL4
DgiDB (Drug Gene Interaction Database)KIR2DL4
DoCM (Curated mutations)KIR2DL4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KIR2DL4 (select a term)
intoGenKIR2DL4
Cancer3DKIR2DL4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604945   
Orphanet
MedgenKIR2DL4
Genetic Testing Registry KIR2DL4
NextProtQ99706 [Medical]
TSGene3805
GENETestsKIR2DL4
Huge Navigator KIR2DL4 [HugePedia]
snp3D : Map Gene to Disease3805
BioCentury BCIQKIR2DL4
ClinGenKIR2DL4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3805
Chemical/Pharm GKB GenePA30117
Clinical trialKIR2DL4
Miscellaneous
canSAR (ICR)KIR2DL4 (select the gene name)
Probes
Litterature
PubMed129 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKIR2DL4
EVEXKIR2DL4
GoPubMedKIR2DL4
iHOPKIR2DL4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 15:06:14 CEST 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.