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KIR2DL5B (killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 5B)

Identity

Alias_nameskiller cell immunoglobulin-like receptor
Alias_symbol (synonym)KIR2DL5.2
KIR2DL5
KIR2DL5.3
KIR2DL5.4
Other aliasKIR2DLX
HGNC (Hugo) KIR2DL5B
LocusID (NCBI) 553128
Atlas_Id 52566
Location 19_KI270921v1_alt  [Link to chromosome band 19]
Location_base_pair Starts at 176150 and ends at 185646 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


External links

Nomenclature
HGNC (Hugo)KIR2DL5B   16346
Cards
Entrez_Gene (NCBI)KIR2DL5B  553128  killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 5B
AliasesKIR2DL5; KIR2DL5.2; KIR2DLX
GeneCards (Weizmann)KIR2DL5B
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr19_KI270921v1_alt:176150-185646 [Contig_View]  KIR2DL5B [Vega]
TCGA cBioPortalKIR2DL5B
AceView (NCBI)KIR2DL5B
Genatlas (Paris)KIR2DL5B
WikiGenes553128
SOURCE (Princeton)KIR2DL5B
Genetics Home Reference (NIH)KIR2DL5B
Genomic and cartography
GoldenPath hg38 (UCSC)KIR2DL5B  -     chr19_KI270921v1_alt:176150-185646 +  19_KI270921v1_alt   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KIR2DL5B  -     19_KI270921v1_alt   [Description]    (hg19-Feb_2009)
EnsemblKIR2DL5B - 19_KI270921v1_alt [CytoView hg19]  KIR2DL5B - 19_KI270921v1_alt [CytoView hg38]
Mapping of homologs : NCBIKIR2DL5B [Mapview hg19]  KIR2DL5B [Mapview hg38]
OMIM615727   
Gene and transcription
Genbank (Entrez)AF271607 AF271608 AJ544587 BC156860
RefSeq transcript (Entrez)NM_001018081
RefSeq genomic (Entrez)NG_005994 NT_187636 NT_187640 NT_187668 NT_187675 NT_187684 NT_187686
Consensus coding sequences : CCDS (NCBI)KIR2DL5B
Cluster EST : UnigeneHs.740906 [ NCBI ]
CGAP (NCI)Hs.740906
Gene ExpressionKIR2DL5B [ NCBI-GEO ]   KIR2DL5B [ EBI - ARRAY_EXPRESS ]   KIR2DL5B [ SEEK ]   KIR2DL5B [ MEM ]
Gene Expression Viewer (FireBrowse)KIR2DL5B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)553128
GTEX Portal (Tissue expression)KIR2DL5B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NHK3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NHK3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NHK3
Splice isoforms : SwissVarQ8NHK3
PhosPhoSitePlusQ8NHK3
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig_sub    Immunoglobulin   
Domain families : Pfam (Sanger)ig (PF00047)   
Domain families : Pfam (NCBI)pfam00047   
Domain families : Smart (EMBL)IG (SM00409)  
Conserved Domain (NCBI)KIR2DL5B
DMDM Disease mutations553128
Blocks (Seattle)KIR2DL5B
SuperfamilyQ8NHK3
Peptide AtlasQ8NHK3
HPRD18687
IPIIPI00604584   
Protein Interaction databases
DIP (DOE-UCLA)Q8NHK3
IntAct (EBI)Q8NHK3
BioGRIDKIR2DL5B
STRING (EMBL)KIR2DL5B
ZODIACKIR2DL5B
Ontologies - Pathways
QuickGOQ8NHK3
Ontology : AmiGOplasma membrane  integral component of membrane  
Ontology : EGO-EBIplasma membrane  integral component of membrane  
NDEx NetworkKIR2DL5B
Atlas of Cancer Signalling NetworkKIR2DL5B
Wikipedia pathwaysKIR2DL5B
Orthology - Evolution
OrthoDB553128
Phylogenetic Trees/Animal Genes : TreeFamKIR2DL5B
HOVERGENQ8NHK3
HOGENOMQ8NHK3
Homologs : HomoloGeneKIR2DL5B
Homology/Alignments : Family Browser (UCSC)KIR2DL5B
Gene fusions - Rearrangements
Tumor Fusion PortalKIR2DL5B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKIR2DL5B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KIR2DL5B
dbVarKIR2DL5B
ClinVarKIR2DL5B
1000_GenomesKIR2DL5B 
Exome Variant ServerKIR2DL5B
ExAC (Exome Aggregation Consortium)
Genetic variants : HAPMAP553128
Genomic Variants (DGV)KIR2DL5B [DGVbeta]
DECIPHERKIR2DL5B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKIR2DL5B 
Mutations
ICGC Data PortalKIR2DL5B 
TCGA Data PortalKIR2DL5B 
Broad Tumor PortalKIR2DL5B
OASIS PortalKIR2DL5B [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDKIR2DL5B
BioMutasearch KIR2DL5B
DgiDB (Drug Gene Interaction Database)KIR2DL5B
DoCM (Curated mutations)KIR2DL5B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KIR2DL5B (select a term)
intoGenKIR2DL5B
Cancer3DKIR2DL5B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615727   
Orphanet
DisGeNETKIR2DL5B
MedgenKIR2DL5B
Genetic Testing Registry KIR2DL5B
NextProtQ8NHK3 [Medical]
TSGene553128
GENETestsKIR2DL5B
Target ValidationKIR2DL5B
Huge Navigator KIR2DL5B [HugePedia]
snp3D : Map Gene to Disease553128
BioCentury BCIQKIR2DL5B
ClinGenKIR2DL5B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD553128
Chemical/Pharm GKB GenePA142671591
Clinical trialKIR2DL5B
Miscellaneous
canSAR (ICR)KIR2DL5B (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKIR2DL5B
EVEXKIR2DL5B
GoPubMedKIR2DL5B
iHOPKIR2DL5B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:18:59 CET 2017

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