KIR2DS2 (killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 2)

2009-09-01  

Identity

HGNC
LOCATION
19q13.42
LOCUSID
ALIAS
183ActI,CD158J,CD158b,KIR-2DS2,KIR2DL1,NKAT-5,NKAT5,cl-49

Other Information

Locus ID:

NCBI: 100132285
MIM: 604953
HGNC: 6334

Variants:

dbSNP: 100132285
ClinVar: 100132285
COSMIC: KIR2DS2

Pathways

PathwaySourceExternal ID
Antigen processing and presentationKEGGko04612
Natural killer cell mediated cytotoxicityKEGGko04650
Antigen processing and presentationKEGGhsa04612
Natural killer cell mediated cytotoxicityKEGGhsa04650
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellREACTOMER-HSA-198933
Innate Immune SystemREACTOMER-HSA-168249
DAP12 interactionsREACTOMER-HSA-2172127

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA164784024peginterferon alfa-2bChemicalMultilinkAnnotationassociated26975229

References

Pubmed IDYearTitleCitations
383872512024Evaluation of the genetic diversity of KIR genes in patients with endometrial cancer.0
383872512024Evaluation of the genetic diversity of KIR genes in patients with endometrial cancer.0
351541532022Killer Cell Immunoglobulin-Like Receptor Haplotype B Modulates Susceptibility to EBV-Associated Classic Hodgkin Lymphoma.4
357681502022KIR2DS2 Expression Identifies NK Cells With Enhanced Anticancer Activity.4
351541532022Killer Cell Immunoglobulin-Like Receptor Haplotype B Modulates Susceptibility to EBV-Associated Classic Hodgkin Lymphoma.4
357681502022KIR2DS2 Expression Identifies NK Cells With Enhanced Anticancer Activity.4
329616332021Clinical and histopathological changes in different KIR gene profiles in chronic HCV Romanian patients.1
329616332021Clinical and histopathological changes in different KIR gene profiles in chronic HCV Romanian patients.1
306895762019KIR2DS2/KIR2DL2/HLA-C1 Haplotype Is Associated with Alzheimer's Disease: Implication for the Role of Herpesvirus Infections.20
306960532019Killer Immunoglobulin-Like Receptor 2DS2 (KIR2DS2), KIR2DL2-HLA-C1, and KIR2DL3 as Genetic Markers for Stratifying the Risk of Cytomegalovirus Infection in Kidney Transplant Recipients.7
306895762019KIR2DS2/KIR2DL2/HLA-C1 Haplotype Is Associated with Alzheimer's Disease: Implication for the Role of Herpesvirus Infections.20
306960532019Killer Immunoglobulin-Like Receptor 2DS2 (KIR2DS2), KIR2DL2-HLA-C1, and KIR2DL3 as Genetic Markers for Stratifying the Risk of Cytomegalovirus Infection in Kidney Transplant Recipients.7
295492932018Prognostic role of KIR genes and HLA-C after hematopoietic stem cell transplantation in a patient cohort with acute myeloid leukemia from a consanguineous community.5
295492932018Prognostic role of KIR genes and HLA-C after hematopoietic stem cell transplantation in a patient cohort with acute myeloid leukemia from a consanguineous community.5
276317282017Association of the genetic diversity of killer cell immunoglobulin-like receptor genes and HLA-C ligand in Saudi women with breast cancer.6

Citation

Dessen P

KIR2DS2 (killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 2)

Atlas Genet Cytogenet Oncol Haematol. 2009-09-01

Online version: http://atlasgeneticsoncology.org/gene/51106/kir2ds2