Atlas of Genetics and Cytogenetics in Oncology and Haematology


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KIR2DS2 (killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 2)

Identity

Alias_nameskiller cell immunoglobulin-like receptor
Alias_symbol (synonym)cl-49
nkat5
183ActI
CD158J
Other aliasCD158b
KIR-2DS2
NKAT-5
NKAT5
HGNC (Hugo) KIR2DS2
LocusID (NCBI) 100132285
Atlas_Id 51106
Location 19q13.42  [Link to chromosome band 19q13]
Location_base_pair Starts at 54738511 and ends at 54848566 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KIR2DS2   6334
Cards
Entrez_Gene (NCBI)KIR2DS2  100132285  killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 2
Aliases183ActI; CD158J; CD158b; KIR-2DS2; 
NKAT-5; NKAT5; cl-49
GeneCards (Weizmann)KIR2DS2
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr19:54738511-54848566 [Contig_View]  KIR2DS2 [Vega]
TCGA cBioPortalKIR2DS2
AceView (NCBI)KIR2DS2
Genatlas (Paris)KIR2DS2
WikiGenes100132285
SOURCE (Princeton)KIR2DS2
Genetics Home Reference (NIH)KIR2DS2
Genomic and cartography
GoldenPath hg38 (UCSC)KIR2DS2  -     chr19:54738511-54848566 +  19q13.42   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KIR2DS2  -     19q13.42   [Description]    (hg19-Feb_2009)
EnsemblKIR2DS2 - 19q13.42 [CytoView hg19]  KIR2DS2 - 19q13.42 [CytoView hg38]
Mapping of homologs : NCBIKIR2DS2 [Mapview hg19]  KIR2DS2 [Mapview hg38]
OMIM604953   
Gene and transcription
Genbank (Entrez)AF074087 AF135565 AF285438 AJ002102 AJ002103
RefSeq transcript (Entrez)NM_001291695 NM_001291696 NM_001291700 NM_001291701 NM_012312
RefSeq genomic (Entrez)NG_005994 NT_113949 NT_187636 NT_187638 NT_187640 NT_187642 NT_187644 NT_187668 NT_187670 NT_187675 NT_187677 NT_187686 NW_003571056 NW_003571061
Consensus coding sequences : CCDS (NCBI)KIR2DS2
Cluster EST : UnigeneHs.731378 [ NCBI ]
CGAP (NCI)Hs.731378
Gene ExpressionKIR2DS2 [ NCBI-GEO ]   KIR2DS2 [ EBI - ARRAY_EXPRESS ]   KIR2DS2 [ SEEK ]   KIR2DS2 [ MEM ]
Gene Expression Viewer (FireBrowse)KIR2DS2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)100132285
GTEX Portal (Tissue expression)KIR2DS2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP43631   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP43631  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP43631
Splice isoforms : SwissVarP43631
PhosPhoSitePlusP43631
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig_sub    Immunoglobulin   
Domain families : Pfam (Sanger)ig (PF00047)   
Domain families : Pfam (NCBI)pfam00047   
Domain families : Smart (EMBL)IG (SM00409)  
Conserved Domain (NCBI)KIR2DS2
DMDM Disease mutations100132285
Blocks (Seattle)KIR2DS2
PDB (SRS)1M4K    4N8V   
PDB (PDBSum)1M4K    4N8V   
PDB (IMB)1M4K    4N8V   
PDB (RSDB)1M4K    4N8V   
Structural Biology KnowledgeBase1M4K    4N8V   
SCOP (Structural Classification of Proteins)1M4K    4N8V   
CATH (Classification of proteins structures)1M4K    4N8V   
SuperfamilyP43631
Peptide AtlasP43631
IPIIPI00956336   IPI00382594   IPI00383384   IPI00011658   
Protein Interaction databases
DIP (DOE-UCLA)P43631
IntAct (EBI)P43631
BioGRIDKIR2DS2
STRING (EMBL)KIR2DS2
ZODIACKIR2DS2
Ontologies - Pathways
QuickGOP43631
Ontology : AmiGOtransmembrane signaling receptor activity  plasma membrane  immune response  signal transduction  integral component of membrane  innate immune response  regulation of immune response  
Ontology : EGO-EBItransmembrane signaling receptor activity  plasma membrane  immune response  signal transduction  integral component of membrane  innate immune response  regulation of immune response  
Pathways : KEGGAntigen processing and presentation    Natural killer cell mediated cytotoxicity   
NDEx NetworkKIR2DS2
Atlas of Cancer Signalling NetworkKIR2DS2
Wikipedia pathwaysKIR2DS2
Orthology - Evolution
OrthoDB100132285
Phylogenetic Trees/Animal Genes : TreeFamKIR2DS2
HOVERGENP43631
HOGENOMP43631
Homologs : HomoloGeneKIR2DS2
Homology/Alignments : Family Browser (UCSC)KIR2DS2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKIR2DS2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KIR2DS2
dbVarKIR2DS2
ClinVarKIR2DS2
1000_GenomesKIR2DS2 
Exome Variant ServerKIR2DS2
ExAC (Exome Aggregation Consortium)KIR2DS2 (select the gene name)
Genetic variants : HAPMAP100132285
Genomic Variants (DGV)KIR2DS2 [DGVbeta]
DECIPHERKIR2DS2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKIR2DS2 
Mutations
ICGC Data PortalKIR2DS2 
TCGA Data PortalKIR2DS2 
Broad Tumor PortalKIR2DS2
OASIS PortalKIR2DS2 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDKIR2DS2
BioMutasearch KIR2DS2
DgiDB (Drug Gene Interaction Database)KIR2DS2
DoCM (Curated mutations)KIR2DS2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KIR2DS2 (select a term)
intoGenKIR2DS2
Cancer3DKIR2DS2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604953   
Orphanet
MedgenKIR2DS2
Genetic Testing Registry KIR2DS2
NextProtP43631 [Medical]
TSGene100132285
GENETestsKIR2DS2
Target ValidationKIR2DS2
Huge Navigator KIR2DS2 [HugePedia]
snp3D : Map Gene to Disease100132285
BioCentury BCIQKIR2DS2
ClinGenKIR2DS2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD100132285
Chemical/Pharm GKB GenePA30119
Clinical trialKIR2DS2
Miscellaneous
canSAR (ICR)KIR2DS2 (select the gene name)
Probes
Litterature
PubMed149 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKIR2DS2
EVEXKIR2DS2
GoPubMedKIR2DS2
iHOPKIR2DS2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:14:33 CEST 2017

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