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KIR2DS4 (killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4)

Identity

Alias_nameskiller cell immunoglobulin-like receptor
Alias_symbol (synonym)cl-39
KKA3
nkat8
CD158i
Other aliasCD158I
KIR-2DS4
KIR1D
KIR412
NKAT-8
NKAT8
HGNC (Hugo) KIR2DS4
LocusID (NCBI) 3809
Atlas_Id 46006
Location 19q13.42  [Link to chromosome band 19q13]
Location_base_pair Starts at 54832676 and ends at 54848569 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KIR2DS4   6336
Cards
Entrez_Gene (NCBI)KIR2DS4  3809  killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4
AliasesCD158I; KIR-2DS4; KIR1D; KIR412; 
KKA3; NKAT-8; NKAT8
GeneCards (Weizmann)KIR2DS4
Ensembl hg19 (Hinxton)ENSG00000221957 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000221957 [Gene_View]  chr19:54832676-54848569 [Contig_View]  KIR2DS4 [Vega]
ICGC DataPortalENSG00000221957
TCGA cBioPortalKIR2DS4
AceView (NCBI)KIR2DS4
Genatlas (Paris)KIR2DS4
WikiGenes3809
SOURCE (Princeton)KIR2DS4
Genetics Home Reference (NIH)KIR2DS4
Genomic and cartography
GoldenPath hg38 (UCSC)KIR2DS4  -     chr19:54832676-54848569 +  19q13.42   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KIR2DS4  -     19q13.42   [Description]    (hg19-Feb_2009)
EnsemblKIR2DS4 - 19q13.42 [CytoView hg19]  KIR2DS4 - 19q13.42 [CytoView hg38]
Mapping of homologs : NCBIKIR2DS4 [Mapview hg19]  KIR2DS4 [Mapview hg38]
OMIM604955   
Gene and transcription
Genbank (Entrez)AF002255 AF135563 AF135564 AJ417554 AJ417555
RefSeq transcript (Entrez)NM_001281971 NM_001281972 NM_012314
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KIR2DS4
Cluster EST : UnigeneHs.744319 [ NCBI ]
CGAP (NCI)Hs.744319
Alternative Splicing GalleryENSG00000221957
Gene ExpressionKIR2DS4 [ NCBI-GEO ]   KIR2DS4 [ EBI - ARRAY_EXPRESS ]   KIR2DS4 [ SEEK ]   KIR2DS4 [ MEM ]
Gene Expression Viewer (FireBrowse)KIR2DS4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3809
GTEX Portal (Tissue expression)KIR2DS4
Protein : pattern, domain, 3D structure
UniProt/SwissProtP43632   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP43632  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP43632
Splice isoforms : SwissVarP43632
PhosPhoSitePlusP43632
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig_sub    Immunoglobulin   
Domain families : Pfam (Sanger)ig (PF00047)   
Domain families : Pfam (NCBI)pfam00047   
Domain families : Smart (EMBL)IG (SM00409)  
Conserved Domain (NCBI)KIR2DS4
DMDM Disease mutations3809
Blocks (Seattle)KIR2DS4
PDB (SRS)3H8N   
PDB (PDBSum)3H8N   
PDB (IMB)3H8N   
PDB (RSDB)3H8N   
Structural Biology KnowledgeBase3H8N   
SCOP (Structural Classification of Proteins)3H8N   
CATH (Classification of proteins structures)3H8N   
SuperfamilyP43632
Human Protein AtlasENSG00000221957
Peptide AtlasP43632
HPRD05387
IPIIPI00019905   IPI00384704   IPI01009226   IPI00410627   
Protein Interaction databases
DIP (DOE-UCLA)P43632
IntAct (EBI)P43632
FunCoupENSG00000221957
BioGRIDKIR2DS4
STRING (EMBL)KIR2DS4
ZODIACKIR2DS4
Ontologies - Pathways
QuickGOP43632
Ontology : AmiGOplasma membrane  integral component of plasma membrane  innate immune response  
Ontology : EGO-EBIplasma membrane  integral component of plasma membrane  innate immune response  
Pathways : KEGGAntigen processing and presentation    Natural killer cell mediated cytotoxicity   
NDEx NetworkKIR2DS4
Atlas of Cancer Signalling NetworkKIR2DS4
Wikipedia pathwaysKIR2DS4
Orthology - Evolution
OrthoDB3809
GeneTree (enSembl)ENSG00000221957
Phylogenetic Trees/Animal Genes : TreeFamKIR2DS4
HOVERGENP43632
HOGENOMP43632
Homologs : HomoloGeneKIR2DS4
Homology/Alignments : Family Browser (UCSC)KIR2DS4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKIR2DS4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KIR2DS4
dbVarKIR2DS4
ClinVarKIR2DS4
1000_GenomesKIR2DS4 
Exome Variant ServerKIR2DS4
ExAC (Exome Aggregation Consortium)KIR2DS4 (select the gene name)
Genetic variants : HAPMAP3809
Genomic Variants (DGV)KIR2DS4 [DGVbeta]
DECIPHERKIR2DS4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKIR2DS4 
Mutations
ICGC Data PortalKIR2DS4 
TCGA Data PortalKIR2DS4 
Broad Tumor PortalKIR2DS4
OASIS PortalKIR2DS4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKIR2DS4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKIR2DS4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KIR2DS4
DgiDB (Drug Gene Interaction Database)KIR2DS4
DoCM (Curated mutations)KIR2DS4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KIR2DS4 (select a term)
intoGenKIR2DS4
Cancer3DKIR2DS4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604955   
Orphanet
MedgenKIR2DS4
Genetic Testing Registry KIR2DS4
NextProtP43632 [Medical]
TSGene3809
GENETestsKIR2DS4
Target ValidationKIR2DS4
Huge Navigator KIR2DS4 [HugePedia]
snp3D : Map Gene to Disease3809
BioCentury BCIQKIR2DS4
ClinGenKIR2DS4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3809
Chemical/Pharm GKB GenePA30121
Clinical trialKIR2DS4
Miscellaneous
canSAR (ICR)KIR2DS4 (select the gene name)
Probes
Litterature
PubMed121 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKIR2DS4
EVEXKIR2DS4
GoPubMedKIR2DS4
iHOPKIR2DS4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:14:34 CEST 2017

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