KIR2DS5 (killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 5)

2008-10-01  

Identity

HGNC
KIR2DS5
LOCATION
19q13.42
LOCUSID
3810
ALIAS
CD158G,NKAT9

Other Information

Locus ID:

NCBI: 3810
MIM: 604956
HGNC: 6337

Variants:

dbSNP: 3810
ClinVar: 3810
COSMIC: KIR2DS5

Pathways

PathwaySourceExternal ID
Antigen processing and presentationKEGGko04612
Natural killer cell mediated cytotoxicityKEGGko04650
Antigen processing and presentationKEGGhsa04612
Natural killer cell mediated cytotoxicityKEGGhsa04650
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
DAP12 interactionsREACTOMER-HSA-2172127

References

Pubmed IDYearTitleCitations
189459622009Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia.166
199342972009KIR and HLA genotypes are associated with disease progression and survival following autologous hematopoietic stem cell transplantation for high-risk neuroblastoma.50
208784002010Association of KIR2DS1 and KIR2DS3 with fatal outcome in Ebola virus infection.32
198465352010Effect of killer immunoglobulin-like receptors in the response to combined treatment in patients with chronic hepatitis C virus infection.31
186242902008Evidence that the KIR2DS5 gene codes for a surface receptor triggering natural killer cell function.24
190322282008Natural killer cell receptor repertoire and their ligands, and the risk of CMV infection after kidney transplantation.22
198611442010Activating killer cell immunoglobulin-like receptors 3DS1 and 2DS1 protect against developing the severe form of recurrent respiratory papillomatosis.22
203318342010Report from the killer immunoglobulin-like receptor (KIR) anthropology component of the 15th International Histocompatibility Workshop: worldwide variation in the KIR loci and further evidence for the co-evolution of KIR and HLA.22
196300742009Killer immunoglobulin-like receptor ligand HLA-Bw4 protects against multiple sclerosis.20
158962042005Distribution of killer cell immunoglobulin-like receptor genes in the Chinese Han population.19

Citation

Dessen P

KIR2DS5 (killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 5)

Atlas Genet Cytogenet Oncol Haematol. 2008-10-01

Online version: http://atlasgeneticsoncology.org/gene/50403/kir2ds5