Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

KLF1 (Kruppel like factor 1)

Identity

Alias_namesKruppel-like factor 1 (erythroid)
Alias_symbol (synonym)EKLF
Other alias
HGNC (Hugo) KLF1
LocusID (NCBI) 10661
Atlas_Id 56559
Location 19p13.2  [Link to chromosome band 19p13]
Location_base_pair Starts at 12995237 and ends at 12998017 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KLF1   6345
LRG (Locus Reference Genomic)LRG_825
Cards
Entrez_Gene (NCBI)KLF1  10661  Kruppel like factor 1
AliasesEKLF
GeneCards (Weizmann)KLF1
Ensembl hg19 (Hinxton)ENSG00000105610 [Gene_View]  chr19:12995237-12998017 [Contig_View]  KLF1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000105610 [Gene_View]  chr19:12995237-12998017 [Contig_View]  KLF1 [Vega]
ICGC DataPortalENSG00000105610
TCGA cBioPortalKLF1
AceView (NCBI)KLF1
Genatlas (Paris)KLF1
WikiGenes10661
SOURCE (Princeton)KLF1
Genetics Home Reference (NIH)KLF1
Genomic and cartography
GoldenPath hg19 (UCSC)KLF1  -     chr19:12995237-12998017 -  19p13.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)KLF1  -     19p13.2   [Description]    (hg38-Dec_2013)
EnsemblKLF1 - 19p13.2 [CytoView hg19]  KLF1 - 19p13.2 [CytoView hg38]
Mapping of homologs : NCBIKLF1 [Mapview hg19]  KLF1 [Mapview hg38]
OMIM111150   600599   613566   613673   
Gene and transcription
Genbank (Entrez)-
RefSeq transcript (Entrez)NM_006563
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KLF1
Cluster EST : UnigeneHs.37860 [ NCBI ]
CGAP (NCI)Hs.37860
Alternative Splicing GalleryENSG00000105610
Gene ExpressionKLF1 [ NCBI-GEO ]   KLF1 [ EBI - ARRAY_EXPRESS ]   KLF1 [ SEEK ]   KLF1 [ MEM ]
Gene Expression Viewer (FireBrowse)KLF1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10661
GTEX Portal (Tissue expression)KLF1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13351   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13351  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13351
Splice isoforms : SwissVarQ13351
PhosPhoSitePlusQ13351
Domaine pattern : Prosite (Expaxy)ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)EKLF_TAD1    EKLF_TAD2    Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)EKLF_TAD1 (PF16832)    EKLF_TAD2 (PF16833)    zf-C2H2 (PF00096)   
Domain families : Pfam (NCBI)pfam16832    pfam16833    pfam00096   
Domain families : Smart (EMBL)ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)KLF1
DMDM Disease mutations10661
Blocks (Seattle)KLF1
PDB (SRS)2L2I    2MBH    2N23   
PDB (PDBSum)2L2I    2MBH    2N23   
PDB (IMB)2L2I    2MBH    2N23   
PDB (RSDB)2L2I    2MBH    2N23   
Structural Biology KnowledgeBase2L2I    2MBH    2N23   
SCOP (Structural Classification of Proteins)2L2I    2MBH    2N23   
CATH (Classification of proteins structures)2L2I    2MBH    2N23   
SuperfamilyQ13351
Human Protein AtlasENSG00000105610
Peptide AtlasQ13351
HPRD07197
IPIIPI00012816   
Protein Interaction databases
DIP (DOE-UCLA)Q13351
IntAct (EBI)Q13351
FunCoupENSG00000105610
BioGRIDKLF1
STRING (EMBL)KLF1
ZODIACKLF1
Ontologies - Pathways
QuickGOQ13351
Ontology : AmiGOnuclear chromatin  core promoter proximal region sequence-specific DNA binding  transcription factor activity, sequence-specific DNA binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  erythrocyte differentiation  transcription regulatory region DNA binding  positive regulation of transcription, DNA-templated  metal ion binding  maternal process involved in female pregnancy  cellular response to peptide  
Ontology : EGO-EBInuclear chromatin  core promoter proximal region sequence-specific DNA binding  transcription factor activity, sequence-specific DNA binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  erythrocyte differentiation  transcription regulatory region DNA binding  positive regulation of transcription, DNA-templated  metal ion binding  maternal process involved in female pregnancy  cellular response to peptide  
NDEx NetworkKLF1
Atlas of Cancer Signalling NetworkKLF1
Wikipedia pathwaysKLF1
Orthology - Evolution
OrthoDB10661
GeneTree (enSembl)ENSG00000105610
Phylogenetic Trees/Animal Genes : TreeFamKLF1
HOVERGENQ13351
HOGENOMQ13351
Homologs : HomoloGeneKLF1
Homology/Alignments : Family Browser (UCSC)KLF1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKLF1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KLF1
dbVarKLF1
ClinVarKLF1
1000_GenomesKLF1 
Exome Variant ServerKLF1
ExAC (Exome Aggregation Consortium)KLF1 (select the gene name)
Genetic variants : HAPMAP10661
Genomic Variants (DGV)KLF1 [DGVbeta]
DECIPHER (Syndromes)19:12995237-12998017  ENSG00000105610
CONAN: Copy Number AnalysisKLF1 
Mutations
ICGC Data PortalKLF1 
TCGA Data PortalKLF1 
Broad Tumor PortalKLF1
OASIS PortalKLF1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKLF1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKLF1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)The Globin Gene Server
BioMutasearch KLF1
DgiDB (Drug Gene Interaction Database)KLF1
DoCM (Curated mutations)KLF1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KLF1 (select a term)
intoGenKLF1
Cancer3DKLF1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM111150    600599    613566    613673   
Orphanet19638    20875    10601   
MedgenKLF1
Genetic Testing Registry KLF1
NextProtQ13351 [Medical]
TSGene10661
GENETestsKLF1
Huge Navigator KLF1 [HugePedia]
snp3D : Map Gene to Disease10661
BioCentury BCIQKLF1
ClinGenKLF1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10661
Chemical/Pharm GKB GenePA30131
Clinical trialKLF1
Miscellaneous
canSAR (ICR)KLF1 (select the gene name)
Probes
Litterature
PubMed71 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKLF1
EVEXKLF1
GoPubMedKLF1
iHOPKLF1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 15:06:17 CEST 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.