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KLF11 (Kruppel like factor 11)

Identity

Alias (NCBI)FKLF
FKLF1
MODY7
TIEG2
Tieg3
HGNC (Hugo) KLF11
HGNC Alias symbTieg3
MODY7
HGNC Previous nameTIEG2
HGNC Previous nameTGFB inducible early growth response 2
LocusID (NCBI) 8462
Atlas_Id 53276
Location 2p25.1  [Link to chromosome band 2p25]
Location_base_pair Starts at 10043550 and ends at 10054836 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
KLF11 (2p25.1) / DCP2 (5q22.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)KLF11   11811
Cards
Entrez_Gene (NCBI)KLF11    Kruppel like factor 11
AliasesFKLF; FKLF1; MODY7; TIEG2; 
Tieg3
GeneCards (Weizmann)KLF11
Ensembl hg19 (Hinxton)ENSG00000172059 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000172059 [Gene_View]  ENSG00000172059 [Sequence]  chr2:10043550-10054836 [Contig_View]  KLF11 [Vega]
ICGC DataPortalENSG00000172059
TCGA cBioPortalKLF11
AceView (NCBI)KLF11
Genatlas (Paris)KLF11
SOURCE (Princeton)KLF11
Genetics Home Reference (NIH)KLF11
Genomic and cartography
GoldenPath hg38 (UCSC)KLF11  -     chr2:10043550-10054836 +  2p25.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KLF11  -     2p25.1   [Description]    (hg19-Feb_2009)
GoldenPathKLF11 - 2p25.1 [CytoView hg19]  KLF11 - 2p25.1 [CytoView hg38]
ImmunoBaseENSG00000172059
Genome Data Viewer NCBIKLF11 [Mapview hg19]  
OMIM603301   610508   
Gene and transcription
Genbank (Entrez)AF028008 AF272830 AI183650 AI755210 AJ275989
RefSeq transcript (Entrez)NM_001177716 NM_001177718 NM_003597
Consensus coding sequences : CCDS (NCBI)KLF11
Gene ExpressionKLF11 [ NCBI-GEO ]   KLF11 [ EBI - ARRAY_EXPRESS ]   KLF11 [ SEEK ]   KLF11 [ MEM ]
Gene Expression Viewer (FireBrowse)KLF11 [ Firebrowse - Broad ]
GenevisibleExpression of KLF11 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8462
GTEX Portal (Tissue expression)KLF11
Human Protein AtlasENSG00000172059-KLF11 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO14901   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO14901  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO14901
PhosPhoSitePlusO14901
Domaine pattern : Prosite (Expaxy)ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)Znf_C2H2_sf    Znf_C2H2_type   
Domain families : Pfam (Sanger)zf-C2H2 (PF00096)   
Domain families : Pfam (NCBI)pfam00096   
Domain families : Smart (EMBL)ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)KLF11
PDB (RSDB)1PO4   
PDB Europe1PO4   
PDB (PDBSum)1PO4   
PDB (IMB)1PO4   
Structural Biology KnowledgeBase1PO4   
SCOP (Structural Classification of Proteins)1PO4   
CATH (Classification of proteins structures)1PO4   
SuperfamilyO14901
AlphaFold pdb e-kbO14901   
Human Protein Atlas [tissue]ENSG00000172059-KLF11 [tissue]
HPRD04488
Protein Interaction databases
DIP (DOE-UCLA)O14901
IntAct (EBI)O14901
BioGRIDKLF11
STRING (EMBL)KLF11
ZODIACKLF11
Ontologies - Pathways
QuickGOO14901
Ontology : AmiGOregulation of transcription involved in G1/S transition of mitotic cell cycle  negative regulation of transcription by RNA polymerase II  chromatin  transcription cis-regulatory region binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity  protein binding  nucleus  nucleoplasm  cytosol  focal adhesion  regulation of transcription by RNA polymerase II  apoptotic process  negative regulation of cell population proliferation  nuclear body  positive regulation of apoptotic process  metal ion binding  cellular response to peptide  sequence-specific double-stranded DNA binding  
Ontology : EGO-EBIregulation of transcription involved in G1/S transition of mitotic cell cycle  negative regulation of transcription by RNA polymerase II  chromatin  transcription cis-regulatory region binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity  protein binding  nucleus  nucleoplasm  cytosol  focal adhesion  regulation of transcription by RNA polymerase II  apoptotic process  negative regulation of cell population proliferation  nuclear body  positive regulation of apoptotic process  metal ion binding  cellular response to peptide  sequence-specific double-stranded DNA binding  
NDEx NetworkKLF11
Atlas of Cancer Signalling NetworkKLF11
Wikipedia pathwaysKLF11
Orthology - Evolution
OrthoDB8462
GeneTree (enSembl)ENSG00000172059
Phylogenetic Trees/Animal Genes : TreeFamKLF11
Homologs : HomoloGeneKLF11
Homology/Alignments : Family Browser (UCSC)KLF11
Gene fusions - Rearrangements
Fusion : QuiverKLF11
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKLF11 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KLF11
dbVarKLF11
ClinVarKLF11
MonarchKLF11
1000_GenomesKLF11 
Exome Variant ServerKLF11
GNOMAD BrowserENSG00000172059
Varsome BrowserKLF11
ACMGKLF11 variants
VarityO14901
Genomic Variants (DGV)KLF11 [DGVbeta]
DECIPHERKLF11 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKLF11 
Mutations
ICGC Data PortalKLF11 
TCGA Data PortalKLF11 
Broad Tumor PortalKLF11
OASIS PortalKLF11 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKLF11  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DKLF11
Mutations and Diseases : HGMDKLF11
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaKLF11
DgiDB (Drug Gene Interaction Database)KLF11
DoCM (Curated mutations)KLF11
CIViC (Clinical Interpretations of Variants in Cancer)KLF11
Cancer3DKLF11
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603301    610508   
Orphanet8028   
DisGeNETKLF11
MedgenKLF11
Genetic Testing Registry KLF11
NextProtO14901 [Medical]
GENETestsKLF11
Target ValidationKLF11
Huge Navigator KLF11 [HugePedia]
ClinGenKLF11
Clinical trials, drugs, therapy
MyCancerGenomeKLF11
Protein Interactions : CTDKLF11
Pharm GKB GenePA36518
PharosO14901
Clinical trialKLF11
Miscellaneous
canSAR (ICR)KLF11
HarmonizomeKLF11
DataMed IndexKLF11
Probes
Litterature
PubMed66 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXKLF11
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:15:07 CEST 2021

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