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KLF11 (Kruppel like factor 11)

Identity

Alias_namesTIEG2
TGFB inducible early growth response 2
Alias_symbol (synonym)Tieg3
MODY7
Other aliasFKLF
FKLF1
HGNC (Hugo) KLF11
LocusID (NCBI) 8462
Atlas_Id 53276
Location 2p25.1  [Link to chromosome band 2p25]
Location_base_pair Starts at 10043829 and ends at 10054836 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
KLF11 (2p25.1) / DCP2 (5q22.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KLF11   11811
Cards
Entrez_Gene (NCBI)KLF11  8462  Kruppel like factor 11
AliasesFKLF; FKLF1; MODY7; TIEG2; 
Tieg3
GeneCards (Weizmann)KLF11
Ensembl hg19 (Hinxton)ENSG00000172059 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000172059 [Gene_View]  chr2:10043829-10054836 [Contig_View]  KLF11 [Vega]
ICGC DataPortalENSG00000172059
TCGA cBioPortalKLF11
AceView (NCBI)KLF11
Genatlas (Paris)KLF11
WikiGenes8462
SOURCE (Princeton)KLF11
Genetics Home Reference (NIH)KLF11
Genomic and cartography
GoldenPath hg38 (UCSC)KLF11  -     chr2:10043829-10054836 +  2p25.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KLF11  -     2p25.1   [Description]    (hg19-Feb_2009)
EnsemblKLF11 - 2p25.1 [CytoView hg19]  KLF11 - 2p25.1 [CytoView hg38]
Mapping of homologs : NCBIKLF11 [Mapview hg19]  KLF11 [Mapview hg38]
OMIM603301   610508   
Gene and transcription
Genbank (Entrez)AF028008 AF272830 AI183650 AI755210 AJ275989
RefSeq transcript (Entrez)NM_001177716 NM_001177718 NM_003597
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KLF11
Cluster EST : UnigeneHs.12229 [ NCBI ]
CGAP (NCI)Hs.12229
Alternative Splicing GalleryENSG00000172059
Gene ExpressionKLF11 [ NCBI-GEO ]   KLF11 [ EBI - ARRAY_EXPRESS ]   KLF11 [ SEEK ]   KLF11 [ MEM ]
Gene Expression Viewer (FireBrowse)KLF11 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8462
GTEX Portal (Tissue expression)KLF11
Protein : pattern, domain, 3D structure
UniProt/SwissProtO14901   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO14901  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO14901
Splice isoforms : SwissVarO14901
PhosPhoSitePlusO14901
Domaine pattern : Prosite (Expaxy)ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)zf-C2H2 (PF00096)   
Domain families : Pfam (NCBI)pfam00096   
Domain families : Smart (EMBL)ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)KLF11
DMDM Disease mutations8462
Blocks (Seattle)KLF11
PDB (SRS)1PO4   
PDB (PDBSum)1PO4   
PDB (IMB)1PO4   
PDB (RSDB)1PO4   
Structural Biology KnowledgeBase1PO4   
SCOP (Structural Classification of Proteins)1PO4   
CATH (Classification of proteins structures)1PO4   
SuperfamilyO14901
Human Protein AtlasENSG00000172059
Peptide AtlasO14901
HPRD04488
IPIIPI00024692   IPI00892850   IPI00892974   IPI00892719   
Protein Interaction databases
DIP (DOE-UCLA)O14901
IntAct (EBI)O14901
FunCoupENSG00000172059
BioGRIDKLF11
STRING (EMBL)KLF11
ZODIACKLF11
Ontologies - Pathways
QuickGOO14901
Ontology : AmiGOregulation of transcription involved in G1/S transition of mitotic cell cycle  negative regulation of transcription from RNA polymerase II promoter  RNA polymerase II transcription factor activity, sequence-specific DNA binding  transcription factor activity, sequence-specific DNA binding  protein binding  nucleus  nucleoplasm  cytosol  focal adhesion  transcription from RNA polymerase II promoter  apoptotic process  negative regulation of cell proliferation  nuclear body  positive regulation of apoptotic process  transcription regulatory region DNA binding  metal ion binding  cellular response to peptide  
Ontology : EGO-EBIregulation of transcription involved in G1/S transition of mitotic cell cycle  negative regulation of transcription from RNA polymerase II promoter  RNA polymerase II transcription factor activity, sequence-specific DNA binding  transcription factor activity, sequence-specific DNA binding  protein binding  nucleus  nucleoplasm  cytosol  focal adhesion  transcription from RNA polymerase II promoter  apoptotic process  negative regulation of cell proliferation  nuclear body  positive regulation of apoptotic process  transcription regulatory region DNA binding  metal ion binding  cellular response to peptide  
NDEx NetworkKLF11
Atlas of Cancer Signalling NetworkKLF11
Wikipedia pathwaysKLF11
Orthology - Evolution
OrthoDB8462
GeneTree (enSembl)ENSG00000172059
Phylogenetic Trees/Animal Genes : TreeFamKLF11
HOVERGENO14901
HOGENOMO14901
Homologs : HomoloGeneKLF11
Homology/Alignments : Family Browser (UCSC)KLF11
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKLF11 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KLF11
dbVarKLF11
ClinVarKLF11
1000_GenomesKLF11 
Exome Variant ServerKLF11
ExAC (Exome Aggregation Consortium)KLF11 (select the gene name)
Genetic variants : HAPMAP8462
Genomic Variants (DGV)KLF11 [DGVbeta]
DECIPHERKLF11 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKLF11 
Mutations
ICGC Data PortalKLF11 
TCGA Data PortalKLF11 
Broad Tumor PortalKLF11
OASIS PortalKLF11 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKLF11  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKLF11
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KLF11
DgiDB (Drug Gene Interaction Database)KLF11
DoCM (Curated mutations)KLF11 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KLF11 (select a term)
intoGenKLF11
Cancer3DKLF11(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603301    610508   
Orphanet8028   
MedgenKLF11
Genetic Testing Registry KLF11
NextProtO14901 [Medical]
TSGene8462
GENETestsKLF11
Target ValidationKLF11
Huge Navigator KLF11 [HugePedia]
snp3D : Map Gene to Disease8462
BioCentury BCIQKLF11
ClinGenKLF11
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8462
Chemical/Pharm GKB GenePA36518
Clinical trialKLF11
Miscellaneous
canSAR (ICR)KLF11 (select the gene name)
Probes
Litterature
PubMed52 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKLF11
EVEXKLF11
GoPubMedKLF11
iHOPKLF11
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:04:46 CEST 2017

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