Atlas of Genetics and Cytogenetics in Oncology and Haematology


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KLF3 (Kruppel-like factor 3 (basic))

Identity

Alias_namesKruppel-like factor 3 (basic)
Alias_symbol (synonym)BKLF
Other alias
HGNC (Hugo) KLF3
LocusID (NCBI) 51274
Atlas_Id 52364
Location 4p14  [Link to chromosome band 4p14]
Location_base_pair Starts at 38665790 and ends at 38703129 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CYLD (16q12.1) / KLF3 (4p14)KLF3 (4p14) / HBG1 (11p15.4)KLF3 (4p14) / SCFD2 (4q12)
KLF3 4p14 / SCFD2 4q12

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KLF3   16516
Cards
Entrez_Gene (NCBI)KLF3  51274  Kruppel-like factor 3 (basic)
AliasesBKLF
GeneCards (Weizmann)KLF3
Ensembl hg19 (Hinxton)ENSG00000109787 [Gene_View]  chr4:38665790-38703129 [Contig_View]  KLF3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000109787 [Gene_View]  chr4:38665790-38703129 [Contig_View]  KLF3 [Vega]
ICGC DataPortalENSG00000109787
TCGA cBioPortalKLF3
AceView (NCBI)KLF3
Genatlas (Paris)KLF3
WikiGenes51274
SOURCE (Princeton)KLF3
Genetics Home Reference (NIH)KLF3
Genomic and cartography
GoldenPath hg19 (UCSC)KLF3  -     chr4:38665790-38703129 +  4p14   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)KLF3  -     4p14   [Description]    (hg38-Dec_2013)
EnsemblKLF3 - 4p14 [CytoView hg19]  KLF3 - 4p14 [CytoView hg38]
Mapping of homologs : NCBIKLF3 [Mapview hg19]  KLF3 [Mapview hg38]
OMIM609392   
Gene and transcription
Genbank (Entrez)AB024523 AF285837 AK313459 BC030662 BC051687
RefSeq transcript (Entrez)NM_016531
RefSeq genomic (Entrez)NC_000004 NC_018915 NT_006238 NW_004929317
Consensus coding sequences : CCDS (NCBI)KLF3
Cluster EST : UnigeneHs.298658 [ NCBI ]
CGAP (NCI)Hs.298658
Alternative Splicing GalleryENSG00000109787
Gene ExpressionKLF3 [ NCBI-GEO ]   KLF3 [ EBI - ARRAY_EXPRESS ]   KLF3 [ SEEK ]   KLF3 [ MEM ]
Gene Expression Viewer (FireBrowse)KLF3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51274
GTEX Portal (Tissue expression)KLF3
Protein : pattern, domain, 3D structure
UniProt/SwissProtP57682   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP57682  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP57682
Splice isoforms : SwissVarP57682
PhosPhoSitePlusP57682
Domaine pattern : Prosite (Expaxy)ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)zf-C2H2 (PF00096)   
Domain families : Pfam (NCBI)pfam00096   
Domain families : Smart (EMBL)ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)KLF3
DMDM Disease mutations51274
Blocks (Seattle)KLF3
SuperfamilyP57682
Human Protein AtlasENSG00000109787
Peptide AtlasP57682
HPRD13920
IPIIPI00027726   IPI00607675   
Protein Interaction databases
DIP (DOE-UCLA)P57682
IntAct (EBI)P57682
FunCoupENSG00000109787
BioGRIDKLF3
STRING (EMBL)KLF3
ZODIACKLF3
Ontologies - Pathways
QuickGOP57682
Ontology : AmiGODNA binding  transcription factor activity, sequence-specific DNA binding  protein binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  multicellular organism development  metal ion binding  cellular response to peptide  
Ontology : EGO-EBIDNA binding  transcription factor activity, sequence-specific DNA binding  protein binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  multicellular organism development  metal ion binding  cellular response to peptide  
Pathways : KEGGTranscriptional misregulation in cancer   
NDEx NetworkKLF3
Atlas of Cancer Signalling NetworkKLF3
Wikipedia pathwaysKLF3
Orthology - Evolution
OrthoDB51274
GeneTree (enSembl)ENSG00000109787
Phylogenetic Trees/Animal Genes : TreeFamKLF3
HOVERGENP57682
HOGENOMP57682
Homologs : HomoloGeneKLF3
Homology/Alignments : Family Browser (UCSC)KLF3
Gene fusions - Rearrangements
Fusion: TCGAKLF3 4p14 SCFD2 4q12 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKLF3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KLF3
dbVarKLF3
ClinVarKLF3
1000_GenomesKLF3 
Exome Variant ServerKLF3
ExAC (Exome Aggregation Consortium)KLF3 (select the gene name)
Genetic variants : HAPMAP51274
Genomic Variants (DGV)KLF3 [DGVbeta]
DECIPHER (Syndromes)4:38665790-38703129  ENSG00000109787
CONAN: Copy Number AnalysisKLF3 
Mutations
ICGC Data PortalKLF3 
TCGA Data PortalKLF3 
Broad Tumor PortalKLF3
OASIS PortalKLF3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKLF3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKLF3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KLF3
DgiDB (Drug Gene Interaction Database)KLF3
DoCM (Curated mutations)KLF3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KLF3 (select a term)
intoGenKLF3
Cancer3DKLF3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609392   
Orphanet
MedgenKLF3
Genetic Testing Registry KLF3
NextProtP57682 [Medical]
TSGene51274
GENETestsKLF3
Huge Navigator KLF3 [HugePedia]
snp3D : Map Gene to Disease51274
BioCentury BCIQKLF3
ClinGenKLF3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51274
Chemical/Pharm GKB GenePA30137
Clinical trialKLF3
Miscellaneous
canSAR (ICR)KLF3 (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKLF3
EVEXKLF3
GoPubMedKLF3
iHOPKLF3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:12:03 CET 2017

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