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KLF7 (Kruppel like factor 7)

Identity

Alias_namesKruppel-like factor 7 (ubiquitous)
Alias_symbol (synonym)UKLF
Other alias
HGNC (Hugo) KLF7
LocusID (NCBI) 8609
Atlas_Id 64951
Location 2q33.3  [Link to chromosome band 2q33]
Location_base_pair Starts at 207074138 and ends at 207166856 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
KLF7 (2q33.3) / PARD3B (2q33.3)KLF7 (2q33.3) / WDR48 (3p22.2)MAP4 (3p21.31) / KLF7 (2q33.3)
TSPAN2 (1p13.2) / KLF7 (2q33.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KLF7   6350
Cards
Entrez_Gene (NCBI)KLF7  8609  Kruppel like factor 7
AliasesUKLF
GeneCards (Weizmann)KLF7
Ensembl hg19 (Hinxton)ENSG00000118263 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000118263 [Gene_View]  chr2:207074138-207166856 [Contig_View]  KLF7 [Vega]
ICGC DataPortalENSG00000118263
TCGA cBioPortalKLF7
AceView (NCBI)KLF7
Genatlas (Paris)KLF7
WikiGenes8609
SOURCE (Princeton)KLF7
Genetics Home Reference (NIH)KLF7
Genomic and cartography
GoldenPath hg38 (UCSC)KLF7  -     chr2:207074138-207166856 -  2q33.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KLF7  -     2q33.3   [Description]    (hg19-Feb_2009)
EnsemblKLF7 - 2q33.3 [CytoView hg19]  KLF7 - 2q33.3 [CytoView hg38]
Mapping of homologs : NCBIKLF7 [Mapview hg19]  KLF7 [Mapview hg38]
OMIM604865   
Gene and transcription
Genbank (Entrez)AB015132 AK000969 AK027371 AK297312 AK314439
RefSeq transcript (Entrez)NM_001270942 NM_001270943 NM_001270944 NM_003709
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KLF7
Cluster EST : UnigeneHs.471221 [ NCBI ]
CGAP (NCI)Hs.471221
Alternative Splicing GalleryENSG00000118263
Gene ExpressionKLF7 [ NCBI-GEO ]   KLF7 [ EBI - ARRAY_EXPRESS ]   KLF7 [ SEEK ]   KLF7 [ MEM ]
Gene Expression Viewer (FireBrowse)KLF7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8609
GTEX Portal (Tissue expression)KLF7
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75840   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75840  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75840
Splice isoforms : SwissVarO75840
PhosPhoSitePlusO75840
Domaine pattern : Prosite (Expaxy)ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)KLF7
DMDM Disease mutations8609
Blocks (Seattle)KLF7
SuperfamilyO75840
Human Protein AtlasENSG00000118263
Peptide AtlasO75840
HPRD07279
IPIIPI00027176   IPI00925975   IPI00925156   IPI00924494   IPI00925563   IPI00925554   IPI00925780   IPI00926385   
Protein Interaction databases
DIP (DOE-UCLA)O75840
IntAct (EBI)O75840
FunCoupENSG00000118263
BioGRIDKLF7
STRING (EMBL)KLF7
ZODIACKLF7
Ontologies - Pathways
QuickGOO75840
Ontology : AmiGORNA polymerase II core promoter proximal region sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  transcription factor activity, sequence-specific DNA binding  transcription coactivator activity  nucleus  regulation of transcription from RNA polymerase II promoter  transcription from RNA polymerase II promoter  axon guidance  zinc ion binding  positive regulation of transcription from RNA polymerase II promoter  dendrite morphogenesis  
Ontology : EGO-EBIRNA polymerase II core promoter proximal region sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  transcription factor activity, sequence-specific DNA binding  transcription coactivator activity  nucleus  regulation of transcription from RNA polymerase II promoter  transcription from RNA polymerase II promoter  axon guidance  zinc ion binding  positive regulation of transcription from RNA polymerase II promoter  dendrite morphogenesis  
NDEx NetworkKLF7
Atlas of Cancer Signalling NetworkKLF7
Wikipedia pathwaysKLF7
Orthology - Evolution
OrthoDB8609
GeneTree (enSembl)ENSG00000118263
Phylogenetic Trees/Animal Genes : TreeFamKLF7
HOVERGENO75840
HOGENOMO75840
Homologs : HomoloGeneKLF7
Homology/Alignments : Family Browser (UCSC)KLF7
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKLF7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KLF7
dbVarKLF7
ClinVarKLF7
1000_GenomesKLF7 
Exome Variant ServerKLF7
ExAC (Exome Aggregation Consortium)KLF7 (select the gene name)
Genetic variants : HAPMAP8609
Genomic Variants (DGV)KLF7 [DGVbeta]
DECIPHERKLF7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKLF7 
Mutations
ICGC Data PortalKLF7 
TCGA Data PortalKLF7 
Broad Tumor PortalKLF7
OASIS PortalKLF7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKLF7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKLF7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KLF7
DgiDB (Drug Gene Interaction Database)KLF7
DoCM (Curated mutations)KLF7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KLF7 (select a term)
intoGenKLF7
Cancer3DKLF7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604865   
Orphanet
MedgenKLF7
Genetic Testing Registry KLF7
NextProtO75840 [Medical]
TSGene8609
GENETestsKLF7
Target ValidationKLF7
Huge Navigator KLF7 [HugePedia]
snp3D : Map Gene to Disease8609
BioCentury BCIQKLF7
ClinGenKLF7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8609
Chemical/Pharm GKB GenePA30140
Clinical trialKLF7
Miscellaneous
canSAR (ICR)KLF7 (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKLF7
EVEXKLF7
GoPubMedKLF7
iHOPKLF7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 16:18:30 CEST 2017

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