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KLHDC3 (kelch domain containing 3)

Identity

Alias_symbol (synonym)PEAS
hPeas
dJ20C7.3
Other alias
HGNC (Hugo) KLHDC3
LocusID (NCBI) 116138
Atlas_Id 64954
Location 6p21.1  [Link to chromosome band 6p21]
Location_base_pair Starts at 43014103 and ends at 43021298 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
KLHDC3 (6p21.1) / ATN1 (12p13.31)KLHDC3 (6p21.1) / CTNND2 (5p15.2)KLHDC3 (6p21.1) / KLHDC3 (6p21.1)
SORT1 (1p13.3) / KLHDC3 (6p21.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KLHDC3   20704
Cards
Entrez_Gene (NCBI)KLHDC3  116138  kelch domain containing 3
AliasesPEAS; dJ20C7.3
GeneCards (Weizmann)KLHDC3
Ensembl hg19 (Hinxton)ENSG00000124702 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000124702 [Gene_View]  ENSG00000124702 [Sequence]  chr6:43014103-43021298 [Contig_View]  KLHDC3 [Vega]
ICGC DataPortalENSG00000124702
TCGA cBioPortalKLHDC3
AceView (NCBI)KLHDC3
Genatlas (Paris)KLHDC3
WikiGenes116138
SOURCE (Princeton)KLHDC3
Genetics Home Reference (NIH)KLHDC3
Genomic and cartography
GoldenPath hg38 (UCSC)KLHDC3  -     chr6:43014103-43021298 +  6p21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KLHDC3  -     6p21.1   [Description]    (hg19-Feb_2009)
EnsemblKLHDC3 - 6p21.1 [CytoView hg19]  KLHDC3 - 6p21.1 [CytoView hg38]
Mapping of homologs : NCBIKLHDC3 [Mapview hg19]  KLHDC3 [Mapview hg38]
OMIM611248   
Gene and transcription
Genbank (Entrez)AB055925 AK097719 AK290384 AK302336 AK308917
RefSeq transcript (Entrez)NM_001242872 NM_057161
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KLHDC3
Cluster EST : UnigeneHs.412468 [ NCBI ]
CGAP (NCI)Hs.412468
Alternative Splicing GalleryENSG00000124702
Gene ExpressionKLHDC3 [ NCBI-GEO ]   KLHDC3 [ EBI - ARRAY_EXPRESS ]   KLHDC3 [ SEEK ]   KLHDC3 [ MEM ]
Gene Expression Viewer (FireBrowse)KLHDC3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)116138
GTEX Portal (Tissue expression)KLHDC3
Human Protein AtlasENSG00000124702-KLHDC3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BQ90   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BQ90  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BQ90
Splice isoforms : SwissVarQ9BQ90
PhosPhoSitePlusQ9BQ90
Domains : Interpro (EBI)Kelch-typ_b-propeller    Kelch_2   
Domain families : Pfam (Sanger)Kelch_2 (PF07646)   
Domain families : Pfam (NCBI)pfam07646   
Conserved Domain (NCBI)KLHDC3
DMDM Disease mutations116138
Blocks (Seattle)KLHDC3
SuperfamilyQ9BQ90
Human Protein Atlas [tissue]ENSG00000124702-KLHDC3 [tissue]
Peptide AtlasQ9BQ90
HPRD13922
IPIIPI00873434   IPI00909055   IPI00062558   IPI00297926   IPI00333243   
Protein Interaction databases
DIP (DOE-UCLA)Q9BQ90
IntAct (EBI)Q9BQ90
FunCoupENSG00000124702
BioGRIDKLHDC3
STRING (EMBL)KLHDC3
ZODIACKLHDC3
Ontologies - Pathways
QuickGOQ9BQ90
Ontology : AmiGOnuclear chromatin  chromatin binding  protein binding  cytoplasm  cytosol  reciprocal meiotic recombination  IRE1-mediated unfolded protein response  
Ontology : EGO-EBInuclear chromatin  chromatin binding  protein binding  cytoplasm  cytosol  reciprocal meiotic recombination  IRE1-mediated unfolded protein response  
NDEx NetworkKLHDC3
Atlas of Cancer Signalling NetworkKLHDC3
Wikipedia pathwaysKLHDC3
Orthology - Evolution
OrthoDB116138
GeneTree (enSembl)ENSG00000124702
Phylogenetic Trees/Animal Genes : TreeFamKLHDC3
HOVERGENQ9BQ90
HOGENOMQ9BQ90
Homologs : HomoloGeneKLHDC3
Homology/Alignments : Family Browser (UCSC)KLHDC3
Gene fusions - Rearrangements
Fusion : QuiverKLHDC3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKLHDC3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KLHDC3
dbVarKLHDC3
ClinVarKLHDC3
1000_GenomesKLHDC3 
Exome Variant ServerKLHDC3
ExAC (Exome Aggregation Consortium)ENSG00000124702
GNOMAD BrowserENSG00000124702
Varsome BrowserKLHDC3
Genetic variants : HAPMAP116138
Genomic Variants (DGV)KLHDC3 [DGVbeta]
DECIPHERKLHDC3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKLHDC3 
Mutations
ICGC Data PortalKLHDC3 
TCGA Data PortalKLHDC3 
Broad Tumor PortalKLHDC3
OASIS PortalKLHDC3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKLHDC3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKLHDC3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KLHDC3
DgiDB (Drug Gene Interaction Database)KLHDC3
DoCM (Curated mutations)KLHDC3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KLHDC3 (select a term)
intoGenKLHDC3
Cancer3DKLHDC3(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611248   
Orphanet
DisGeNETKLHDC3
MedgenKLHDC3
Genetic Testing Registry KLHDC3
NextProtQ9BQ90 [Medical]
TSGene116138
GENETestsKLHDC3
Target ValidationKLHDC3
Huge Navigator KLHDC3 [HugePedia]
snp3D : Map Gene to Disease116138
BioCentury BCIQKLHDC3
ClinGenKLHDC3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD116138
Chemical/Pharm GKB GenePA134892782
Clinical trialKLHDC3
Miscellaneous
canSAR (ICR)KLHDC3 (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKLHDC3
EVEXKLHDC3
GoPubMedKLHDC3
iHOPKLHDC3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jul 30 13:51:07 CEST 2018

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