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KLHDC4 (kelch domain containing 4)

Identity

Alias (NCBI)-
HGNC (Hugo) KLHDC4
HGNC Alias symbDKFZp434G0522
LocusID (NCBI) 54758
Atlas_Id 55894
Location 16q24.2  [Link to chromosome band 16q24]
Location_base_pair Starts at 87707812 and ends at 87765986 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FAHD1 (16p13.3) / KLHDC4 (16q24.2)KLHDC4 (16q24.2) / CTGF (6q23.2)KLHDC4 (16q24.2) / SPG7 (16q24.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)KLHDC4   25272
Cards
Entrez_Gene (NCBI)KLHDC4    kelch domain containing 4
Aliases
GeneCards (Weizmann)KLHDC4
Ensembl hg19 (Hinxton)ENSG00000104731 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000104731 [Gene_View]  ENSG00000104731 [Sequence]  chr16:87707812-87765986 [Contig_View]  KLHDC4 [Vega]
ICGC DataPortalENSG00000104731
TCGA cBioPortalKLHDC4
AceView (NCBI)KLHDC4
Genatlas (Paris)KLHDC4
SOURCE (Princeton)KLHDC4
Genetics Home Reference (NIH)KLHDC4
Genomic and cartography
GoldenPath hg38 (UCSC)KLHDC4  -     chr16:87707812-87765986 -  16q24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KLHDC4  -     16q24.2   [Description]    (hg19-Feb_2009)
GoldenPathKLHDC4 - 16q24.2 [CytoView hg19]  KLHDC4 - 16q24.2 [CytoView hg38]
ImmunoBaseENSG00000104731
genome Data Viewer NCBIKLHDC4 [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AK001742 AK023986 AK024496 AK057211 AK092895
RefSeq transcript (Entrez)NM_001184854 NM_001184856 NM_001351937 NM_001351938 NM_017566
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KLHDC4
Alternative Splicing GalleryENSG00000104731
Gene ExpressionKLHDC4 [ NCBI-GEO ]   KLHDC4 [ EBI - ARRAY_EXPRESS ]   KLHDC4 [ SEEK ]   KLHDC4 [ MEM ]
Gene Expression Viewer (FireBrowse)KLHDC4 [ Firebrowse - Broad ]
GenevisibleExpression of KLHDC4 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54758
GTEX Portal (Tissue expression)KLHDC4
Human Protein AtlasENSG00000104731-KLHDC4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TBB5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TBB5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TBB5
Splice isoforms : SwissVarQ8TBB5
PhosPhoSitePlusQ8TBB5
Domains : Interpro (EBI)Kelch-typ_b-propeller    Kelch_2   
Domain families : Pfam (Sanger)Kelch_2 (PF07646)   
Domain families : Pfam (NCBI)pfam07646   
Conserved Domain (NCBI)KLHDC4
Blocks (Seattle)KLHDC4
SuperfamilyQ8TBB5
Human Protein Atlas [tissue]ENSG00000104731-KLHDC4 [tissue]
Peptide AtlasQ8TBB5
HPRD11180
IPIIPI00152182   IPI00642250   IPI00304958   IPI00297861   
Protein Interaction databases
DIP (DOE-UCLA)Q8TBB5
IntAct (EBI)Q8TBB5
BioGRIDKLHDC4
STRING (EMBL)KLHDC4
ZODIACKLHDC4
Ontologies - Pathways
QuickGOQ8TBB5
Ontology : AmiGOprotein binding  
Ontology : EGO-EBIprotein binding  
NDEx NetworkKLHDC4
Atlas of Cancer Signalling NetworkKLHDC4
Wikipedia pathwaysKLHDC4
Orthology - Evolution
OrthoDB54758
GeneTree (enSembl)ENSG00000104731
Phylogenetic Trees/Animal Genes : TreeFamKLHDC4
HOGENOMQ8TBB5
Homologs : HomoloGeneKLHDC4
Homology/Alignments : Family Browser (UCSC)KLHDC4
Gene fusions - Rearrangements
Fusion : QuiverKLHDC4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKLHDC4 [hg38]
dbVarKLHDC4
ClinVarKLHDC4
MonarchKLHDC4
1000_GenomesKLHDC4 
Exome Variant ServerKLHDC4
GNOMAD BrowserENSG00000104731
Varsome BrowserKLHDC4
Genomic Variants (DGV)KLHDC4 [DGVbeta]
DECIPHERKLHDC4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKLHDC4 
Mutations
ICGC Data PortalKLHDC4 
TCGA Data PortalKLHDC4 
Broad Tumor PortalKLHDC4
OASIS PortalKLHDC4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKLHDC4  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DKLHDC4
Mutations and Diseases : HGMDKLHDC4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KLHDC4
DgiDB (Drug Gene Interaction Database)KLHDC4
DoCM (Curated mutations)KLHDC4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KLHDC4 (select a term)
intoGenKLHDC4
Cancer3DKLHDC4(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETKLHDC4
MedgenKLHDC4
Genetic Testing Registry KLHDC4
NextProtQ8TBB5 [Medical]
GENETestsKLHDC4
Target ValidationKLHDC4
Huge Navigator KLHDC4 [HugePedia]
ClinGenKLHDC4
Clinical trials, drugs, therapy
MyCancerGenomeKLHDC4
Protein Interactions : CTD
Pharm GKB GenePA134914472
PharosQ8TBB5
Clinical trialKLHDC4
Miscellaneous
canSAR (ICR)KLHDC4 (select the gene name)
HarmonizomeKLHDC4
DataMed IndexKLHDC4
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXKLHDC4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 25 19:28:06 CET 2021
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