Atlas of Genetics and Cytogenetics in Oncology and Haematology


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KLHL10 (kelch like family member 10)

Identity

Alias_nameskelch-like 10 (Drosophila)
Alias_symbol (synonym)FLJ32662
Other aliasSPGF11
HGNC (Hugo) KLHL10
LocusID (NCBI) 317719
Atlas_Id 64958
Location 17q21.2  [Link to chromosome band 17q21]
Location_base_pair Starts at 41835685 and ends at 41848363 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
KLHL10 (17q21.2) / GNPDA1 (5q31.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KLHL10   18829
Cards
Entrez_Gene (NCBI)KLHL10  317719  kelch like family member 10
AliasesSPGF11
GeneCards (Weizmann)KLHL10
Ensembl hg19 (Hinxton)ENSG00000161594 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000161594 [Gene_View]  chr17:41835685-41848363 [Contig_View]  KLHL10 [Vega]
ICGC DataPortalENSG00000161594
TCGA cBioPortalKLHL10
AceView (NCBI)KLHL10
Genatlas (Paris)KLHL10
WikiGenes317719
SOURCE (Princeton)KLHL10
Genetics Home Reference (NIH)KLHL10
Genomic and cartography
GoldenPath hg38 (UCSC)KLHL10  -     chr17:41835685-41848363 +  17q21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KLHL10  -     17q21.2   [Description]    (hg19-Feb_2009)
EnsemblKLHL10 - 17q21.2 [CytoView hg19]  KLHL10 - 17q21.2 [CytoView hg38]
Mapping of homologs : NCBIKLHL10 [Mapview hg19]  KLHL10 [Mapview hg38]
OMIM608778   615081   
Gene and transcription
Genbank (Entrez)AK057224 AK301797 AK302141 AY495339 BC067753
RefSeq transcript (Entrez)NM_001329595 NM_001329596 NM_152467
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KLHL10
Cluster EST : UnigeneHs.127510 [ NCBI ]
CGAP (NCI)Hs.127510
Alternative Splicing GalleryENSG00000161594
Gene ExpressionKLHL10 [ NCBI-GEO ]   KLHL10 [ EBI - ARRAY_EXPRESS ]   KLHL10 [ SEEK ]   KLHL10 [ MEM ]
Gene Expression Viewer (FireBrowse)KLHL10 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)317719
GTEX Portal (Tissue expression)KLHL10
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6JEL2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6JEL2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6JEL2
Splice isoforms : SwissVarQ6JEL2
PhosPhoSitePlusQ6JEL2
Domaine pattern : Prosite (Expaxy)BTB (PS50097)   
Domains : Interpro (EBI)BACK    BTB-kelch_protein    BTB/POZ_dom    Gal_Oxidase_b-propeller    Kelch_1    SKP1/BTB/POZ   
Domain families : Pfam (Sanger)BACK (PF07707)    BTB (PF00651)    Kelch_1 (PF01344)   
Domain families : Pfam (NCBI)pfam07707    pfam00651    pfam01344   
Domain families : Smart (EMBL)BACK (SM00875)  BTB (SM00225)  Kelch (SM00612)  
Conserved Domain (NCBI)KLHL10
DMDM Disease mutations317719
Blocks (Seattle)KLHL10
SuperfamilyQ6JEL2
Human Protein AtlasENSG00000161594
Peptide AtlasQ6JEL2
HPRD12296
IPIIPI00065461   IPI00893738   IPI00893613   
Protein Interaction databases
DIP (DOE-UCLA)Q6JEL2
IntAct (EBI)Q6JEL2
FunCoupENSG00000161594
BioGRIDKLHL10
STRING (EMBL)KLHL10
ZODIACKLHL10
Ontologies - Pathways
QuickGOQ6JEL2
Ontology : AmiGOcell morphogenesis  ubiquitin-protein transferase activity  cytoplasm  spermatid development  male gonad development  fertilization  protein ubiquitination  Cul3-RING ubiquitin ligase complex  male genitalia morphogenesis  homeostasis of number of cells within a tissue  
Ontology : EGO-EBIcell morphogenesis  ubiquitin-protein transferase activity  cytoplasm  spermatid development  male gonad development  fertilization  protein ubiquitination  Cul3-RING ubiquitin ligase complex  male genitalia morphogenesis  homeostasis of number of cells within a tissue  
NDEx NetworkKLHL10
Atlas of Cancer Signalling NetworkKLHL10
Wikipedia pathwaysKLHL10
Orthology - Evolution
OrthoDB317719
GeneTree (enSembl)ENSG00000161594
Phylogenetic Trees/Animal Genes : TreeFamKLHL10
HOVERGENQ6JEL2
HOGENOMQ6JEL2
Homologs : HomoloGeneKLHL10
Homology/Alignments : Family Browser (UCSC)KLHL10
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKLHL10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KLHL10
dbVarKLHL10
ClinVarKLHL10
1000_GenomesKLHL10 
Exome Variant ServerKLHL10
ExAC (Exome Aggregation Consortium)KLHL10 (select the gene name)
Genetic variants : HAPMAP317719
Genomic Variants (DGV)KLHL10 [DGVbeta]
DECIPHERKLHL10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKLHL10 
Mutations
ICGC Data PortalKLHL10 
TCGA Data PortalKLHL10 
Broad Tumor PortalKLHL10
OASIS PortalKLHL10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKLHL10  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKLHL10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KLHL10
DgiDB (Drug Gene Interaction Database)KLHL10
DoCM (Curated mutations)KLHL10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KLHL10 (select a term)
intoGenKLHL10
Cancer3DKLHL10(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608778    615081   
Orphanet
MedgenKLHL10
Genetic Testing Registry KLHL10
NextProtQ6JEL2 [Medical]
TSGene317719
GENETestsKLHL10
Target ValidationKLHL10
Huge Navigator KLHL10 [HugePedia]
snp3D : Map Gene to Disease317719
BioCentury BCIQKLHL10
ClinGenKLHL10
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD317719
Chemical/Pharm GKB GenePA134969977
Clinical trialKLHL10
Miscellaneous
canSAR (ICR)KLHL10 (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKLHL10
EVEXKLHL10
GoPubMedKLHL10
iHOPKLHL10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 18 13:12:00 CEST 2017

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