Atlas of Genetics and Cytogenetics in Oncology and Haematology


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KLHL15 (kelch like family member 15)

Identity

Other aliasHEL-S-305
HGNC (Hugo) KLHL15
LocusID (NCBI) 80311
Atlas_Id 56666
Location Xp22.11  [Link to chromosome band Xp22]
Location_base_pair Starts at 23983716 and ends at 24027186 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ZFX (Xp22.11) / KLHL15 (Xp22.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KLHL15   29347
Cards
Entrez_Gene (NCBI)KLHL15  80311  kelch like family member 15
AliasesHEL-S-305
GeneCards (Weizmann)KLHL15
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chrX:23983716-24027186 [Contig_View]  KLHL15 [Vega]
TCGA cBioPortalKLHL15
AceView (NCBI)KLHL15
Genatlas (Paris)KLHL15
WikiGenes80311
SOURCE (Princeton)KLHL15
Genetics Home Reference (NIH)KLHL15
Genomic and cartography
GoldenPath hg38 (UCSC)KLHL15  -     chrX:23983716-24027186 -  Xp22.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KLHL15  -     Xp22.11   [Description]    (hg19-Feb_2009)
EnsemblKLHL15 - Xp22.11 [CytoView hg19]  KLHL15 - Xp22.11 [CytoView hg38]
Mapping of homologs : NCBIKLHL15 [Mapview hg19]  KLHL15 [Mapview hg38]
OMIM300980   300982   
Gene and transcription
Genbank (Entrez)AA825676 AB051464 AK057298 AL834313 BC015415
RefSeq transcript (Entrez)NM_030624
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KLHL15
Cluster EST : UnigeneHs.495854 [ NCBI ]
CGAP (NCI)Hs.495854
Gene ExpressionKLHL15 [ NCBI-GEO ]   KLHL15 [ EBI - ARRAY_EXPRESS ]   KLHL15 [ SEEK ]   KLHL15 [ MEM ]
Gene Expression Viewer (FireBrowse)KLHL15 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)80311
GTEX Portal (Tissue expression)KLHL15
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96M94   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96M94  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96M94
Splice isoforms : SwissVarQ96M94
PhosPhoSitePlusQ96M94
Domaine pattern : Prosite (Expaxy)BTB (PS50097)   
Domains : Interpro (EBI)BACK    BTB-kelch_protein    BTB/POZ_dom    Kelch-typ_b-propeller    Kelch_1    KLHL15    SKP1/BTB/POZ   
Domain families : Pfam (Sanger)BACK (PF07707)    BTB (PF00651)    Kelch_1 (PF01344)   
Domain families : Pfam (NCBI)pfam07707    pfam00651    pfam01344   
Domain families : Smart (EMBL)BACK (SM00875)  BTB (SM00225)  Kelch (SM00612)  
Conserved Domain (NCBI)KLHL15
DMDM Disease mutations80311
Blocks (Seattle)KLHL15
SuperfamilyQ96M94
Peptide AtlasQ96M94
IPIIPI00307535   
Protein Interaction databases
DIP (DOE-UCLA)Q96M94
IntAct (EBI)Q96M94
BioGRIDKLHL15
STRING (EMBL)KLHL15
ZODIACKLHL15
Ontologies - Pathways
QuickGOQ96M94
Ontology : AmiGOubiquitin-protein transferase activity  protein binding  nucleus  Cul3-RING ubiquitin ligase complex  protein ubiquitination involved in ubiquitin-dependent protein catabolic process  ubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome  negative regulation of double-strand break repair via homologous recombination  
Ontology : EGO-EBIubiquitin-protein transferase activity  protein binding  nucleus  Cul3-RING ubiquitin ligase complex  protein ubiquitination involved in ubiquitin-dependent protein catabolic process  ubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome  negative regulation of double-strand break repair via homologous recombination  
NDEx NetworkKLHL15
Atlas of Cancer Signalling NetworkKLHL15
Wikipedia pathwaysKLHL15
Orthology - Evolution
OrthoDB80311
Phylogenetic Trees/Animal Genes : TreeFamKLHL15
HOVERGENQ96M94
HOGENOMQ96M94
Homologs : HomoloGeneKLHL15
Homology/Alignments : Family Browser (UCSC)KLHL15
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKLHL15 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KLHL15
dbVarKLHL15
ClinVarKLHL15
1000_GenomesKLHL15 
Exome Variant ServerKLHL15
ExAC (Exome Aggregation Consortium)KLHL15 (select the gene name)
Genetic variants : HAPMAP80311
Genomic Variants (DGV)KLHL15 [DGVbeta]
DECIPHERKLHL15 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKLHL15 
Mutations
ICGC Data PortalKLHL15 
TCGA Data PortalKLHL15 
Broad Tumor PortalKLHL15
OASIS PortalKLHL15 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKLHL15  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKLHL15
BioMutasearch KLHL15
DgiDB (Drug Gene Interaction Database)KLHL15
DoCM (Curated mutations)KLHL15 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KLHL15 (select a term)
intoGenKLHL15
Cancer3DKLHL15(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300980    300982   
Orphanet
MedgenKLHL15
Genetic Testing Registry KLHL15
NextProtQ96M94 [Medical]
TSGene80311
GENETestsKLHL15
Target ValidationKLHL15
Huge Navigator KLHL15 [HugePedia]
snp3D : Map Gene to Disease80311
BioCentury BCIQKLHL15
ClinGenKLHL15
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD80311
Chemical/Pharm GKB GenePA134934728
Clinical trialKLHL15
Miscellaneous
canSAR (ICR)KLHL15 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKLHL15
EVEXKLHL15
GoPubMedKLHL15
iHOPKLHL15
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:39:47 CEST 2017

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