Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

KLHL18 (kelch like family member 18)

Identity

Alias_nameskelch-like 18 (Drosophila)
Alias_symbol (synonym)KIAA0795
FLJ13703
Other alias-
HGNC (Hugo) KLHL18
LocusID (NCBI) 23276
Atlas_Id 64965
Location 3p21.31  [Link to chromosome band 3p21]
Location_base_pair Starts at 47282840 and ends at 47346816 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
KLHL18 (3p21.31) / PSMA5 (1p13.3)KLHL18 (3p21.31) / TEX264 (3p21.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KLHL18   29120
Cards
Entrez_Gene (NCBI)KLHL18  23276  kelch like family member 18
Aliases
GeneCards (Weizmann)KLHL18
Ensembl hg19 (Hinxton)ENSG00000114648 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000114648 [Gene_View]  chr3:47282840-47346816 [Contig_View]  KLHL18 [Vega]
ICGC DataPortalENSG00000114648
TCGA cBioPortalKLHL18
AceView (NCBI)KLHL18
Genatlas (Paris)KLHL18
WikiGenes23276
SOURCE (Princeton)KLHL18
Genetics Home Reference (NIH)KLHL18
Genomic and cartography
GoldenPath hg38 (UCSC)KLHL18  -     chr3:47282840-47346816 +  3p21.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KLHL18  -     3p21.31   [Description]    (hg19-Feb_2009)
EnsemblKLHL18 - 3p21.31 [CytoView hg19]  KLHL18 - 3p21.31 [CytoView hg38]
Mapping of homologs : NCBIKLHL18 [Mapview hg19]  KLHL18 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB018338 AB062478 AI356423 AK001337 AK023765
RefSeq transcript (Entrez)NM_025010
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KLHL18
Cluster EST : UnigeneHs.517946 [ NCBI ]
CGAP (NCI)Hs.517946
Alternative Splicing GalleryENSG00000114648
Gene ExpressionKLHL18 [ NCBI-GEO ]   KLHL18 [ EBI - ARRAY_EXPRESS ]   KLHL18 [ SEEK ]   KLHL18 [ MEM ]
Gene Expression Viewer (FireBrowse)KLHL18 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23276
GTEX Portal (Tissue expression)KLHL18
Protein : pattern, domain, 3D structure
UniProt/SwissProtO94889   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO94889  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO94889
Splice isoforms : SwissVarO94889
PhosPhoSitePlusO94889
Domaine pattern : Prosite (Expaxy)BTB (PS50097)   
Domains : Interpro (EBI)BACK    BTB-kelch_protein    BTB/POZ_dom    Gal_Oxidase_b-propeller    Kelch_1    SKP1/BTB/POZ   
Domain families : Pfam (Sanger)BACK (PF07707)    BTB (PF00651)    Kelch_1 (PF01344)   
Domain families : Pfam (NCBI)pfam07707    pfam00651    pfam01344   
Domain families : Smart (EMBL)BACK (SM00875)  BTB (SM00225)  Kelch (SM00612)  
Conserved Domain (NCBI)KLHL18
DMDM Disease mutations23276
Blocks (Seattle)KLHL18
SuperfamilyO94889
Human Protein AtlasENSG00000114648
Peptide AtlasO94889
HPRD10017
IPIIPI00789341   IPI00747824   IPI01010833   IPI00941423   IPI00926214   IPI00925936   IPI00925699   
Protein Interaction databases
DIP (DOE-UCLA)O94889
IntAct (EBI)O94889
FunCoupENSG00000114648
BioGRIDKLHL18
STRING (EMBL)KLHL18
ZODIACKLHL18
Ontologies - Pathways
QuickGOO94889
Ontology : AmiGOubiquitin-protein transferase activity  protein binding  protein ubiquitination  Cul3-RING ubiquitin ligase complex  
Ontology : EGO-EBIubiquitin-protein transferase activity  protein binding  protein ubiquitination  Cul3-RING ubiquitin ligase complex  
NDEx NetworkKLHL18
Atlas of Cancer Signalling NetworkKLHL18
Wikipedia pathwaysKLHL18
Orthology - Evolution
OrthoDB23276
GeneTree (enSembl)ENSG00000114648
Phylogenetic Trees/Animal Genes : TreeFamKLHL18
HOVERGENO94889
HOGENOMO94889
Homologs : HomoloGeneKLHL18
Homology/Alignments : Family Browser (UCSC)KLHL18
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKLHL18 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KLHL18
dbVarKLHL18
ClinVarKLHL18
1000_GenomesKLHL18 
Exome Variant ServerKLHL18
ExAC (Exome Aggregation Consortium)KLHL18 (select the gene name)
Genetic variants : HAPMAP23276
Genomic Variants (DGV)KLHL18 [DGVbeta]
DECIPHERKLHL18 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKLHL18 
Mutations
ICGC Data PortalKLHL18 
TCGA Data PortalKLHL18 
Broad Tumor PortalKLHL18
OASIS PortalKLHL18 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKLHL18  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKLHL18
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KLHL18
DgiDB (Drug Gene Interaction Database)KLHL18
DoCM (Curated mutations)KLHL18 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KLHL18 (select a term)
intoGenKLHL18
Cancer3DKLHL18(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenKLHL18
Genetic Testing Registry KLHL18
NextProtO94889 [Medical]
TSGene23276
GENETestsKLHL18
Target ValidationKLHL18
Huge Navigator KLHL18 [HugePedia]
snp3D : Map Gene to Disease23276
BioCentury BCIQKLHL18
ClinGenKLHL18
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23276
Chemical/Pharm GKB GenePA134920201
Clinical trialKLHL18
Miscellaneous
canSAR (ICR)KLHL18 (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKLHL18
EVEXKLHL18
GoPubMedKLHL18
iHOPKLHL18
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 18 13:12:01 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.