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KLHL2 (kelch-like 2, Mayven (Drosophila))

Identity

Other namesABP-KELCH
MAV
MAYVEN
HGNC (Hugo) KLHL2
LocusID (NCBI) 11275
Location 4q32.3
Location_base_pair Starts at 166131171 and ends at 166244308 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)KLHL2   6353
Entrez_Gene (NCBI)KLHL2  11275  kelch-like 2, Mayven (Drosophila)
Cards
GeneCards (Weizmann)KLHL2
Ensembl (Hinxton)ENSG00000109466 [Gene_View]  chr4:166131171-166244308 [Contig_View]  KLHL2 [Vega]
AceView (NCBI)KLHL2
Genatlas (Paris)KLHL2
SOURCE (Stanford)NM_001161521 NM_001161522 NM_007246
Genomic and cartography
GoldenPath (UCSC)KLHL2  -  4q32.3   chr4:166131171-166244308 +  4q32.3   [Description]    (hg19-Feb_2009)
EnsemblKLHL2 - 4q32.3 [CytoView]
Mapping of homologs : NCBIKLHL2 [Mapview]
OMIM605774   
Gene and transcription
Genbank (Entrez)AB209727 AF059569 AI814691 AK025289 AK294103
RefSeq transcript (SRS)NM_001161521 NM_001161522 NM_007246
RefSeq transcript (Entrez)NM_001161521 NM_001161522 NM_007246
RefSeq genomic (SRS)AC_000136 NC_000004 NC_018915 NT_016354 NW_001838921 NW_004078021
RefSeq genomic (Entrez)AC_000136 NC_000004 NC_018915 NT_016354 NW_001838921 NW_004078021
Consensus coding sequences : CCDS (NCBI)KLHL2
Cluster EST : UnigeneHs.388668 [ SRS ] Hs.388668 [ NCBI ]
CGAP (NCI)Hs.388668
Alternative Splicing : Fast-db (Paris)GSHG0022964
Alternative Splicing GalleryENSG00000109466
Gene ExpressionKLHL2 [ NCBI-GEO ]   KLHL2 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95198 (SRS) O95198 (Uniprot)
NextProtO95198
With graphics : InterProO95198
Splice isoforms : SwissVarO95198(Swissvar)
Domaine pattern : Prosite (SRS)BTB (PS50097)   
Domaine pattern : Prosite (Expaxy)BTB (PS50097)   
Domains : Interpro (SRS)BACK    BTB/POZ-like    BTB/POZ_fold    BTB_POZ    Gal_Oxidase_b-propeller    Kelch-like_gigaxonin    Kelch_1   
Domains : Interpro (EBI)BACK    BTB/POZ-like    BTB/POZ_fold    BTB_POZ    Gal_Oxidase_b-propeller    Kelch-like_gigaxonin    Kelch_1   
Related proteins : CluSTrO95198
Domain families : Pfam (SRS)BACK (PF07707)    BTB (PF00651)    Kelch_1 (PF01344)   
Domain families : Pfam (Sanger)BACK (PF07707)    BTB (PF00651)    Kelch_1 (PF01344)   
Domain families : Pfam (NCBI)pfam07707    pfam00651    pfam01344   
Domain families : Smart (EMBL)BACK (SM00875)  BTB (SM00225)  Kelch (SM00612)  
DMDM11275
Blocks (Seattle)O95198
PDB (SRS)2XN4   
PDB (PDBSum)2XN4   
PDB (IMB)2XN4   
PDB (RSDB)2XN4   
Human Protein AtlasENSG00000109466
HPRD09311
IPIIPI00296591   IPI00936343   IPI00966733   IPI00938152   IPI00966521   IPI00965376   IPI00965819   
Protein Interaction databases
DIP (DOE-UCLA)O95198
IntAct (EBI)O95198
FunCoupENSG00000109466
REACTOMEKLHL2
Protein Interaction Database11275
BioGRIDKLHL2
InParanoidO95198
Interologous Interaction database O95198
IntegromeDBKLHL2
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)KLHL2
SNP (GeneSNP Utah)KLHL2
SNP : HGBaseKLHL2
Genetic variants : HAPMAPKLHL2
Somatic Mutations in Cancer : COSMICKLHL2 
CONAN: Copy Number AnalysisKLHL2 
Mutations and Diseases : HGMDKLHL2
OMIM605774   
GENETests605774   
Disease Genetic AssociationKLHL2
Huge Navigator KLHL2 [HugePedia]  KLHL2 [HugeCancerGEM]
Genomic VariantsKLHL2  KLHL2 [DGVbeta]
snp3D : Map Gene to Disease11275
General knowledge
Homologs : HomoloGeneKLHL2
Homology/Alignments : Family Browser (UCSC)KLHL2
Phylogenetic Trees/Animal Genes : TreeFamKLHL2
Chemical/Protein Interactions : CTD11275
Chemical/Pharm GKB GenePA30143
Clinical trialKLHL2
Cancer Resource (Charite)ENSG00000109466
Ontology : AmiGOactin binding  transporter activity  protein binding  cytoplasm  cytoskeleton  intracellular protein transport  actin cytoskeleton  
Ontology : EGO-EBIactin binding  transporter activity  protein binding  cytoplasm  cytoskeleton  intracellular protein transport  actin cytoskeleton  
Other databases
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
PubGeneKLHL2
iHOPKLHL2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:20:54 CEST 2013
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