Atlas of Genetics and Cytogenetics in Oncology and Haematology


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KLHL21 (kelch-like family member 21)

Identity

Other names-
HGNC (Hugo) KLHL21
LocusID (NCBI) 9903
Location 1p36.31
Location_base_pair Starts at 6650784 and ends at 6662929 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)KLHL21   29041
Cards
Entrez_Gene (NCBI)KLHL21  9903  kelch-like family member 21
GeneCards (Weizmann)KLHL21
Ensembl hg19 (Hinxton)ENSG00000162413 [Gene_View]  chr1:6650784-6662929 [Contig_View]  KLHL21 [Vega]
Ensembl hg38 (Hinxton)ENSG00000162413 [Gene_View]  chr1:6650784-6662929 [Contig_View]  KLHL21 [Vega]
ICGC DataPortalENSG00000162413
cBioPortalKLHL21
AceView (NCBI)KLHL21
Genatlas (Paris)KLHL21
WikiGenes9903
SOURCE (Princeton)KLHL21
Genomic and cartography
GoldenPath hg19 (UCSC)KLHL21  -     chr1:6650784-6662929 -  1p36.31   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)KLHL21  -     1p36.31   [Description]    (hg38-Dec_2013)
EnsemblKLHL21 - 1p36.31 [CytoView hg19]  KLHL21 - 1p36.31 [CytoView hg38]
Mapping of homologs : NCBIKLHL21 [Mapview hg19]  KLHL21 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB007938 AK057164 AK075305 AK090472 AK307564
RefSeq transcript (Entrez)NM_014851
RefSeq genomic (Entrez)AC_000133 NC_000001 NC_018912 NT_032977 NW_001838523 NW_004929289
Consensus coding sequences : CCDS (NCBI)KLHL21
Cluster EST : UnigeneHs.7764 [ NCBI ]
CGAP (NCI)Hs.7764
Alternative Splicing : Fast-db (Paris)GSHG0001716
Alternative Splicing GalleryENSG00000162413
Gene ExpressionKLHL21 [ NCBI-GEO ]     KLHL21 [ SEEK ]   KLHL21 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UJP4 (Uniprot)
NextProtQ9UJP4  [Medical]
With graphics : InterProQ9UJP4
Splice isoforms : SwissVarQ9UJP4 (Swissvar)
Domaine pattern : Prosite (Expaxy)BTB (PS50097)   
Domains : Interpro (EBI)BACK    BTB/POZ-like    BTB/POZ_fold    BTB_POZ    Gal_Oxidase_b-propeller    Kelch-like_gigaxonin-typ    Kelch_1   
Related proteins : CluSTrQ9UJP4
Domain families : Pfam (Sanger)BACK (PF07707)    BTB (PF00651)    Kelch_1 (PF01344)   
Domain families : Pfam (NCBI)pfam07707    pfam00651    pfam01344   
Domain families : Smart (EMBL)BACK (SM00875)  BTB (SM00225)  Kelch (SM00612)  
DMDM Disease mutations9903
Blocks (Seattle)Q9UJP4
Human Protein AtlasENSG00000162413
Peptide AtlasQ9UJP4
HPRD17239
IPIIPI00402021   IPI00006994   IPI01009309   
Protein Interaction databases
DIP (DOE-UCLA)Q9UJP4
IntAct (EBI)Q9UJP4
FunCoupENSG00000162413
BioGRIDKLHL21
IntegromeDBKLHL21
STRING (EMBL)KLHL21
Ontologies - Pathways
QuickGOQ9UJP4
Ontology : AmiGOubiquitin-protein transferase activity  cytoplasm  polar microtubule  mitotic nuclear division  protein ubiquitination  protein ubiquitination  Cul3-RING ubiquitin ligase complex  regulation of cytokinesis  chromosome passenger complex localization to spindle midzone  
Ontology : EGO-EBIubiquitin-protein transferase activity  cytoplasm  polar microtubule  mitotic nuclear division  protein ubiquitination  protein ubiquitination  Cul3-RING ubiquitin ligase complex  regulation of cytokinesis  chromosome passenger complex localization to spindle midzone  
Protein Interaction DatabaseKLHL21
DoCM (Curated mutations)KLHL21
Wikipedia pathwaysKLHL21
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerKLHL21 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KLHL21
dbVarKLHL21
ClinVarKLHL21
1000_GenomesKLHL21 
Exome Variant ServerKLHL21
SNP (GeneSNP Utah)KLHL21
SNP : HGBaseKLHL21
Genetic variants : HAPMAPKLHL21
Genomic VariantsKLHL21  KLHL21 [DGVbeta]
Mutations
ICGC Data PortalENSG00000162413 
Somatic Mutations in Cancer : COSMICKLHL21 
CONAN: Copy Number AnalysisKLHL21 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)1:6650784-6662929
Mutations and Diseases : HGMDKLHL21
OMIM
MedgenKLHL21
NextProtQ9UJP4 [Medical]
GENETestsKLHL21
Disease Genetic AssociationKLHL21
Huge Navigator KLHL21 [HugePedia]  KLHL21 [HugeCancerGEM]
snp3D : Map Gene to Disease9903
DGIdb (Drug Gene Interaction db)KLHL21
General knowledge
Homologs : HomoloGeneKLHL21
Homology/Alignments : Family Browser (UCSC)KLHL21
Phylogenetic Trees/Animal Genes : TreeFamKLHL21
Chemical/Protein Interactions : CTD9903
Chemical/Pharm GKB GenePA134989246
Clinical trialKLHL21
Cancer Resource (Charite)ENSG00000162413
Other databases
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
CoreMineKLHL21
GoPubMedKLHL21
iHOPKLHL21
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Dec 20 22:19:58 CET 2014

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