Atlas of Genetics and Cytogenetics in Oncology and Haematology


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KLHL23 (kelch like family member 23)

Identity

Alias (NCBI)DITHP
HGNC (Hugo) KLHL23
HGNC Alias symbMGC2610
FLJ37812
MGC22679
HGNC Previous namekelch-like 23 (Drosophila)
LocusID (NCBI) 151230
Atlas_Id 64967
Location 2q31.1  [Link to chromosome band 2q31]
Location_base_pair Starts at 169733832 and ends at 169751878 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)KLHL23   27506
Cards
Entrez_Gene (NCBI)KLHL23    kelch like family member 23
AliasesDITHP
GeneCards (Weizmann)KLHL23
Ensembl hg19 (Hinxton)ENSG00000213160 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000213160 [Gene_View]  ENSG00000213160 [Sequence]  chr2:169733832-169751878 [Contig_View]  KLHL23 [Vega]
ICGC DataPortalENSG00000213160
TCGA cBioPortalKLHL23
AceView (NCBI)KLHL23
Genatlas (Paris)KLHL23
SOURCE (Princeton)KLHL23
Genetics Home Reference (NIH)KLHL23
Genomic and cartography
GoldenPath hg38 (UCSC)KLHL23  -     chr2:169733832-169751878 +  2q31.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KLHL23  -     2q31.1   [Description]    (hg19-Feb_2009)
GoldenPathKLHL23 - 2q31.1 [CytoView hg19]  KLHL23 - 2q31.1 [CytoView hg38]
ImmunoBaseENSG00000213160
Genome Data Viewer NCBIKLHL23 [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AK095131 AK123454 BC010437 BC016950 BE326381
RefSeq transcript (Entrez)NM_144711
Consensus coding sequences : CCDS (NCBI)KLHL23
Gene ExpressionKLHL23 [ NCBI-GEO ]   KLHL23 [ EBI - ARRAY_EXPRESS ]   KLHL23 [ SEEK ]   KLHL23 [ MEM ]
Gene Expression Viewer (FireBrowse)KLHL23 [ Firebrowse - Broad ]
GenevisibleExpression of KLHL23 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)151230
GTEX Portal (Tissue expression)KLHL23
Human Protein AtlasENSG00000213160-KLHL23 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NBE8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NBE8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NBE8
PhosPhoSitePlusQ8NBE8
Domaine pattern : Prosite (Expaxy)BTB (PS50097)   
Domains : Interpro (EBI)BACK    BTB-kelch_protein    BTB/POZ_dom    Kelch-typ_b-propeller    Kelch_1    SKP1/BTB/POZ_sf   
Domain families : Pfam (Sanger)BACK (PF07707)    BTB (PF00651)    Kelch_1 (PF01344)   
Domain families : Pfam (NCBI)pfam07707    pfam00651    pfam01344   
Domain families : Smart (EMBL)BACK (SM00875)  BTB (SM00225)  Kelch (SM00612)  
Conserved Domain (NCBI)KLHL23
SuperfamilyQ8NBE8
AlphaFold pdb e-kbQ8NBE8   
Human Protein Atlas [tissue]ENSG00000213160-KLHL23 [tissue]
HPRD11320
Protein Interaction databases
DIP (DOE-UCLA)Q8NBE8
IntAct (EBI)Q8NBE8
BioGRIDKLHL23
STRING (EMBL)KLHL23
ZODIACKLHL23
Ontologies - Pathways
QuickGOQ8NBE8
Ontology : AmiGOprotein binding  
Ontology : EGO-EBIprotein binding  
NDEx NetworkKLHL23
Atlas of Cancer Signalling NetworkKLHL23
Wikipedia pathwaysKLHL23
Orthology - Evolution
OrthoDB151230
GeneTree (enSembl)ENSG00000213160
Phylogenetic Trees/Animal Genes : TreeFamKLHL23
Homologs : HomoloGeneKLHL23
Homology/Alignments : Family Browser (UCSC)KLHL23
Gene fusions - Rearrangements
Fusion : QuiverKLHL23
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKLHL23 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KLHL23
dbVarKLHL23
ClinVarKLHL23
MonarchKLHL23
1000_GenomesKLHL23 
Exome Variant ServerKLHL23
GNOMAD BrowserENSG00000213160
Varsome BrowserKLHL23
ACMGKLHL23 variants
VarityQ8NBE8
Genomic Variants (DGV)KLHL23 [DGVbeta]
DECIPHERKLHL23 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKLHL23 
Mutations
ICGC Data PortalKLHL23 
TCGA Data PortalKLHL23 
Broad Tumor PortalKLHL23
OASIS PortalKLHL23 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKLHL23  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DKLHL23
Mutations and Diseases : HGMDKLHL23
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaKLHL23
DgiDB (Drug Gene Interaction Database)KLHL23
DoCM (Curated mutations)KLHL23
CIViC (Clinical Interpretations of Variants in Cancer)KLHL23
Cancer3DKLHL23
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETKLHL23
MedgenKLHL23
Genetic Testing Registry KLHL23
NextProtQ8NBE8 [Medical]
GENETestsKLHL23
Target ValidationKLHL23
Huge Navigator KLHL23 [HugePedia]
ClinGenKLHL23
Clinical trials, drugs, therapy
MyCancerGenomeKLHL23
Protein Interactions : CTDKLHL23
Pharm GKB GenePA142671575
PharosQ8NBE8
Clinical trialKLHL23
Miscellaneous
canSAR (ICR)KLHL23
HarmonizomeKLHL23
DataMed IndexKLHL23
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXKLHL23
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:54:45 CEST 2021

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