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KLHL23 (kelch like family member 23)

Identity

Alias_nameskelch-like 23 (Drosophila)
Alias_symbol (synonym)MGC2610
FLJ37812
MGC22679
Other aliasDITHP
HGNC (Hugo) KLHL23
LocusID (NCBI) 151230
Atlas_Id 64967
Location 2q31.1  [Link to chromosome band 2q31]
Location_base_pair Starts at 169733846 and ends at 169751886 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KLHL23   27506
Cards
Entrez_Gene (NCBI)KLHL23  151230  kelch like family member 23
AliasesDITHP
GeneCards (Weizmann)KLHL23
Ensembl hg19 (Hinxton)ENSG00000213160 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000213160 [Gene_View]  chr2:169733846-169751886 [Contig_View]  KLHL23 [Vega]
ICGC DataPortalENSG00000213160
TCGA cBioPortalKLHL23
AceView (NCBI)KLHL23
Genatlas (Paris)KLHL23
WikiGenes151230
SOURCE (Princeton)KLHL23
Genetics Home Reference (NIH)KLHL23
Genomic and cartography
GoldenPath hg38 (UCSC)KLHL23  -     chr2:169733846-169751886 +  2q31.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KLHL23  -     2q31.1   [Description]    (hg19-Feb_2009)
EnsemblKLHL23 - 2q31.1 [CytoView hg19]  KLHL23 - 2q31.1 [CytoView hg38]
Mapping of homologs : NCBIKLHL23 [Mapview hg19]  KLHL23 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK095131 AK123454 BC010437 BC016950 BE326381
RefSeq transcript (Entrez)NM_144711
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KLHL23
Cluster EST : UnigeneHs.745233 [ NCBI ]
CGAP (NCI)Hs.745233
Alternative Splicing GalleryENSG00000213160
Gene ExpressionKLHL23 [ NCBI-GEO ]   KLHL23 [ EBI - ARRAY_EXPRESS ]   KLHL23 [ SEEK ]   KLHL23 [ MEM ]
Gene Expression Viewer (FireBrowse)KLHL23 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)151230
GTEX Portal (Tissue expression)KLHL23
Human Protein AtlasENSG00000213160-KLHL23 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NBE8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NBE8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NBE8
Splice isoforms : SwissVarQ8NBE8
PhosPhoSitePlusQ8NBE8
Domaine pattern : Prosite (Expaxy)BTB (PS50097)   
Domains : Interpro (EBI)BACK    BTB-kelch_protein    BTB/POZ_dom    Gal_Oxidase_b-propeller    Kelch_1    SKP1/BTB/POZ   
Domain families : Pfam (Sanger)BACK (PF07707)    BTB (PF00651)    Kelch_1 (PF01344)   
Domain families : Pfam (NCBI)pfam07707    pfam00651    pfam01344   
Domain families : Smart (EMBL)BACK (SM00875)  BTB (SM00225)  Kelch (SM00612)  
Conserved Domain (NCBI)KLHL23
DMDM Disease mutations151230
Blocks (Seattle)KLHL23
SuperfamilyQ8NBE8
Human Protein Atlas [tissue]ENSG00000213160-KLHL23 [tissue]
Peptide AtlasQ8NBE8
HPRD11320
Protein Interaction databases
DIP (DOE-UCLA)Q8NBE8
IntAct (EBI)Q8NBE8
FunCoupENSG00000213160
BioGRIDKLHL23
STRING (EMBL)KLHL23
ZODIACKLHL23
Ontologies - Pathways
QuickGOQ8NBE8
Ontology : AmiGOubiquitin-protein transferase activity  protein binding  protein ubiquitination  Cul3-RING ubiquitin ligase complex  
Ontology : EGO-EBIubiquitin-protein transferase activity  protein binding  protein ubiquitination  Cul3-RING ubiquitin ligase complex  
NDEx NetworkKLHL23
Atlas of Cancer Signalling NetworkKLHL23
Wikipedia pathwaysKLHL23
Orthology - Evolution
OrthoDB151230
GeneTree (enSembl)ENSG00000213160
Phylogenetic Trees/Animal Genes : TreeFamKLHL23
HOVERGENQ8NBE8
HOGENOMQ8NBE8
Homologs : HomoloGeneKLHL23
Homology/Alignments : Family Browser (UCSC)KLHL23
Gene fusions - Rearrangements
Tumor Fusion PortalKLHL23
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKLHL23 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KLHL23
dbVarKLHL23
ClinVarKLHL23
1000_GenomesKLHL23 
Exome Variant ServerKLHL23
ExAC (Exome Aggregation Consortium)ENSG00000213160
GNOMAD BrowserENSG00000213160
Genetic variants : HAPMAP151230
Genomic Variants (DGV)KLHL23 [DGVbeta]
DECIPHERKLHL23 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKLHL23 
Mutations
ICGC Data PortalKLHL23 
TCGA Data PortalKLHL23 
Broad Tumor PortalKLHL23
OASIS PortalKLHL23 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKLHL23  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKLHL23
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KLHL23
DgiDB (Drug Gene Interaction Database)KLHL23
DoCM (Curated mutations)KLHL23 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KLHL23 (select a term)
intoGenKLHL23
Cancer3DKLHL23(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETKLHL23
MedgenKLHL23
Genetic Testing Registry KLHL23
NextProtQ8NBE8 [Medical]
TSGene151230
GENETestsKLHL23
Target ValidationKLHL23
Huge Navigator KLHL23 [HugePedia]
snp3D : Map Gene to Disease151230
BioCentury BCIQKLHL23
ClinGenKLHL23
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD151230
Chemical/Pharm GKB GenePA142671575
Clinical trialKLHL23
Miscellaneous
canSAR (ICR)KLHL23 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKLHL23
EVEXKLHL23
GoPubMedKLHL23
iHOPKLHL23
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Nov 20 19:35:15 CET 2017

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