Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

KLHL24 (kelch-like family member 24)

Identity

Alias_nameskelch-like 24 (Drosophila)
Alias_symbol (synonym)DRE1
FLJ20059
Other aliasKRIP6
HGNC (Hugo) KLHL24
LocusID (NCBI) 54800
Atlas_Id 64968
Location 3q27.1  [Link to chromosome band 3q27]
Location_base_pair Starts at 183353411 and ends at 183402304 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ABHD6 (3p14.3) / KLHL24 (3q27.1)ARHGEF1 (19q13.2) / KLHL24 (3q27.1)FXR1 (3q26.33) / KLHL24 (3q27.1)
KLHL24 (3q27.1) / CEP89 (19q13.11)KLHL24 (3q27.1) / KLHL24 (3q27.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KLHL24   25947
Cards
Entrez_Gene (NCBI)KLHL24  54800  kelch-like family member 24
AliasesDRE1; KRIP6
GeneCards (Weizmann)KLHL24
Ensembl hg19 (Hinxton)ENSG00000114796 [Gene_View]  chr3:183353411-183402304 [Contig_View]  KLHL24 [Vega]
Ensembl hg38 (Hinxton)ENSG00000114796 [Gene_View]  chr3:183353411-183402304 [Contig_View]  KLHL24 [Vega]
ICGC DataPortalENSG00000114796
TCGA cBioPortalKLHL24
AceView (NCBI)KLHL24
Genatlas (Paris)KLHL24
WikiGenes54800
SOURCE (Princeton)KLHL24
Genetics Home Reference (NIH)KLHL24
Genomic and cartography
GoldenPath hg19 (UCSC)KLHL24  -     chr3:183353411-183402304 +  3q27.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)KLHL24  -     3q27.1   [Description]    (hg38-Dec_2013)
EnsemblKLHL24 - 3q27.1 [CytoView hg19]  KLHL24 - 3q27.1 [CytoView hg38]
Mapping of homologs : NCBIKLHL24 [Mapview hg19]  KLHL24 [Mapview hg38]
OMIM611295   
Gene and transcription
Genbank (Entrez)AK000066 AK024270 AK026326 AK098662 AY422472
RefSeq transcript (Entrez)NM_017644
RefSeq genomic (Entrez)NC_000003 NC_018914 NT_005612 NW_004929311
Consensus coding sequences : CCDS (NCBI)KLHL24
Cluster EST : UnigeneHs.407709 [ NCBI ]
CGAP (NCI)Hs.407709
Alternative Splicing GalleryENSG00000114796
Gene ExpressionKLHL24 [ NCBI-GEO ]   KLHL24 [ EBI - ARRAY_EXPRESS ]   KLHL24 [ SEEK ]   KLHL24 [ MEM ]
Gene Expression Viewer (FireBrowse)KLHL24 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54800
GTEX Portal (Tissue expression)KLHL24
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6TFL4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6TFL4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6TFL4
Splice isoforms : SwissVarQ6TFL4
PhosPhoSitePlusQ6TFL4
Domaine pattern : Prosite (Expaxy)BTB (PS50097)   
Domains : Interpro (EBI)BACK    BTB-kelch_protein    BTB/POZ-like    BTB/POZ_fold    BTB_POZ    Gal_Oxidase_b-propeller    Kelch_1    KLHL24   
Domain families : Pfam (Sanger)BACK (PF07707)    BTB (PF00651)    Kelch_1 (PF01344)   
Domain families : Pfam (NCBI)pfam07707    pfam00651    pfam01344   
Domain families : Smart (EMBL)BACK (SM00875)  BTB (SM00225)  Kelch (SM00612)  
Conserved Domain (NCBI)KLHL24
DMDM Disease mutations54800
Blocks (Seattle)KLHL24
SuperfamilyQ6TFL4
Human Protein AtlasENSG00000114796
Peptide AtlasQ6TFL4
HPRD16838
IPIIPI00165008   IPI00869301   IPI00925732   IPI00925081   IPI00947023   IPI01011754   IPI01010420   IPI00184700   IPI01018210   IPI00945793   
Protein Interaction databases
DIP (DOE-UCLA)Q6TFL4
IntAct (EBI)Q6TFL4
FunCoupENSG00000114796
BioGRIDKLHL24
STRING (EMBL)KLHL24
ZODIACKLHL24
Ontologies - Pathways
QuickGOQ6TFL4
Ontology : AmiGOcytoplasm  axon  perikaryon  regulation of kainate selective glutamate receptor activity  
Ontology : EGO-EBIcytoplasm  axon  perikaryon  regulation of kainate selective glutamate receptor activity  
NDEx NetworkKLHL24
Atlas of Cancer Signalling NetworkKLHL24
Wikipedia pathwaysKLHL24
Orthology - Evolution
OrthoDB54800
GeneTree (enSembl)ENSG00000114796
Phylogenetic Trees/Animal Genes : TreeFamKLHL24
HOVERGENQ6TFL4
HOGENOMQ6TFL4
Homologs : HomoloGeneKLHL24
Homology/Alignments : Family Browser (UCSC)KLHL24
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKLHL24 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KLHL24
dbVarKLHL24
ClinVarKLHL24
1000_GenomesKLHL24 
Exome Variant ServerKLHL24
ExAC (Exome Aggregation Consortium)KLHL24 (select the gene name)
Genetic variants : HAPMAP54800
Genomic Variants (DGV)KLHL24 [DGVbeta]
DECIPHER (Syndromes)3:183353411-183402304  ENSG00000114796
CONAN: Copy Number AnalysisKLHL24 
Mutations
ICGC Data PortalKLHL24 
TCGA Data PortalKLHL24 
Broad Tumor PortalKLHL24
OASIS PortalKLHL24 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKLHL24  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKLHL24
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KLHL24
DgiDB (Drug Gene Interaction Database)KLHL24
DoCM (Curated mutations)KLHL24 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KLHL24 (select a term)
intoGenKLHL24
Cancer3DKLHL24(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611295   
Orphanet
MedgenKLHL24
Genetic Testing Registry KLHL24
NextProtQ6TFL4 [Medical]
TSGene54800
GENETestsKLHL24
Huge Navigator KLHL24 [HugePedia]
snp3D : Map Gene to Disease54800
BioCentury BCIQKLHL24
ClinGenKLHL24
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54800
Chemical/Pharm GKB GenePA142671576
Clinical trialKLHL24
Miscellaneous
canSAR (ICR)KLHL24 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKLHL24
EVEXKLHL24
GoPubMedKLHL24
iHOPKLHL24
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 12:10:01 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.