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KLHL25 (kelch like family member 25)

Identity

Alias_nameskelch-like 25 (Drosophila)
Alias_symbol (synonym)FLJ12587
ENC2
ENC-2
Other alias
HGNC (Hugo) KLHL25
LocusID (NCBI) 64410
Atlas_Id 64969
Location 15q25.3  [Link to chromosome band 15q25]
Location_base_pair Starts at 85759326 and ends at 85794958 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KLHL25   25732
Cards
Entrez_Gene (NCBI)KLHL25  64410  kelch like family member 25
AliasesENC-2; ENC2
GeneCards (Weizmann)KLHL25
Ensembl hg19 (Hinxton)ENSG00000183655 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000183655 [Gene_View]  chr15:85759326-85794958 [Contig_View]  KLHL25 [Vega]
ICGC DataPortalENSG00000183655
TCGA cBioPortalKLHL25
AceView (NCBI)KLHL25
Genatlas (Paris)KLHL25
WikiGenes64410
SOURCE (Princeton)KLHL25
Genetics Home Reference (NIH)KLHL25
Genomic and cartography
GoldenPath hg38 (UCSC)KLHL25  -     chr15:85759326-85794958 -  15q25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KLHL25  -     15q25.3   [Description]    (hg19-Feb_2009)
EnsemblKLHL25 - 15q25.3 [CytoView hg19]  KLHL25 - 15q25.3 [CytoView hg38]
Mapping of homologs : NCBIKLHL25 [Mapview hg19]  KLHL25 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK022649 AK056663 AK092231 AK126962 AK315541
RefSeq transcript (Entrez)NM_022480
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KLHL25
Cluster EST : UnigeneHs.498371 [ NCBI ]
CGAP (NCI)Hs.498371
Alternative Splicing GalleryENSG00000183655
Gene ExpressionKLHL25 [ NCBI-GEO ]   KLHL25 [ EBI - ARRAY_EXPRESS ]   KLHL25 [ SEEK ]   KLHL25 [ MEM ]
Gene Expression Viewer (FireBrowse)KLHL25 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64410
GTEX Portal (Tissue expression)KLHL25
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H0H3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H0H3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H0H3
Splice isoforms : SwissVarQ9H0H3
PhosPhoSitePlusQ9H0H3
Domaine pattern : Prosite (Expaxy)BTB (PS50097)   
Domains : Interpro (EBI)BACK    BTB-kelch_protein    BTB/POZ_dom    Kelch-typ_b-propeller    Kelch_1    KLHL25    SKP1/BTB/POZ   
Domain families : Pfam (Sanger)BACK (PF07707)    BTB (PF00651)    Kelch_1 (PF01344)   
Domain families : Pfam (NCBI)pfam07707    pfam00651    pfam01344   
Domain families : Smart (EMBL)BACK (SM00875)  BTB (SM00225)  Kelch (SM00612)  
Conserved Domain (NCBI)KLHL25
DMDM Disease mutations64410
Blocks (Seattle)KLHL25
SuperfamilyQ9H0H3
Human Protein AtlasENSG00000183655
Peptide AtlasQ9H0H3
HPRD07780
IPIIPI00014320   IPI01009853   
Protein Interaction databases
DIP (DOE-UCLA)Q9H0H3
IntAct (EBI)Q9H0H3
FunCoupENSG00000183655
BioGRIDKLHL25
STRING (EMBL)KLHL25
ZODIACKLHL25
Ontologies - Pathways
QuickGOQ9H0H3
Ontology : AmiGOcytoplasm  regulation of translational initiation  protein ubiquitination  Cul3-RING ubiquitin ligase complex  protein ubiquitination involved in ubiquitin-dependent protein catabolic process  
Ontology : EGO-EBIcytoplasm  regulation of translational initiation  protein ubiquitination  Cul3-RING ubiquitin ligase complex  protein ubiquitination involved in ubiquitin-dependent protein catabolic process  
NDEx NetworkKLHL25
Atlas of Cancer Signalling NetworkKLHL25
Wikipedia pathwaysKLHL25
Orthology - Evolution
OrthoDB64410
GeneTree (enSembl)ENSG00000183655
Phylogenetic Trees/Animal Genes : TreeFamKLHL25
HOVERGENQ9H0H3
HOGENOMQ9H0H3
Homologs : HomoloGeneKLHL25
Homology/Alignments : Family Browser (UCSC)KLHL25
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKLHL25 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KLHL25
dbVarKLHL25
ClinVarKLHL25
1000_GenomesKLHL25 
Exome Variant ServerKLHL25
ExAC (Exome Aggregation Consortium)KLHL25 (select the gene name)
Genetic variants : HAPMAP64410
Genomic Variants (DGV)KLHL25 [DGVbeta]
DECIPHERKLHL25 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKLHL25 
Mutations
ICGC Data PortalKLHL25 
TCGA Data PortalKLHL25 
Broad Tumor PortalKLHL25
OASIS PortalKLHL25 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKLHL25  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKLHL25
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KLHL25
DgiDB (Drug Gene Interaction Database)KLHL25
DoCM (Curated mutations)KLHL25 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KLHL25 (select a term)
intoGenKLHL25
Cancer3DKLHL25(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenKLHL25
Genetic Testing Registry KLHL25
NextProtQ9H0H3 [Medical]
TSGene64410
GENETestsKLHL25
Target ValidationKLHL25
Huge Navigator KLHL25 [HugePedia]
snp3D : Map Gene to Disease64410
BioCentury BCIQKLHL25
ClinGenKLHL25
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64410
Chemical/Pharm GKB GenePA142671577
Clinical trialKLHL25
Miscellaneous
canSAR (ICR)KLHL25 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKLHL25
EVEXKLHL25
GoPubMedKLHL25
iHOPKLHL25
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 18 13:12:02 CEST 2017

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