Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

KLHL29 (kelch like family member 29)

Identity

Alias_namesKBTBD9
kelch repeat and BTB (POZ) domain containing 9
kelch-like 29 (Drosophila)
Alias_symbol (synonym)KIAA1921
Other alias
HGNC (Hugo) KLHL29
LocusID (NCBI) 114818
Atlas_Id 54416
Location 2p24.1  [Link to chromosome band 2p24]
Location_base_pair Starts at 23608298 and ends at 23931483 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
GPN1 (2p23.3) / KLHL29 (2p24.1)ITPK1 (14q32.12) / KLHL29 (2p24.1)KLHL29 (2p24.1) / PSMA8 (18q11.2)
LGALS1 (22q13.1) / KLHL29 (2p24.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Squamous Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)KLHL29   29404
Cards
Entrez_Gene (NCBI)KLHL29  114818  kelch like family member 29
AliasesKBTBD9
GeneCards (Weizmann)KLHL29
Ensembl hg19 (Hinxton)ENSG00000119771 [Gene_View]  chr2:23608298-23931483 [Contig_View]  KLHL29 [Vega]
Ensembl hg38 (Hinxton)ENSG00000119771 [Gene_View]  chr2:23608298-23931483 [Contig_View]  KLHL29 [Vega]
ICGC DataPortalENSG00000119771
TCGA cBioPortalKLHL29
AceView (NCBI)KLHL29
Genatlas (Paris)KLHL29
WikiGenes114818
SOURCE (Princeton)KLHL29
Genetics Home Reference (NIH)KLHL29
Genomic and cartography
GoldenPath hg19 (UCSC)KLHL29  -     chr2:23608298-23931483 +  2p24.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)KLHL29  -     2p24.1   [Description]    (hg38-Dec_2013)
EnsemblKLHL29 - 2p24.1 [CytoView hg19]  KLHL29 - 2p24.1 [CytoView hg38]
Mapping of homologs : NCBIKLHL29 [Mapview hg19]  KLHL29 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA775711 AB067508 AK024168 AK094600 AL834515
RefSeq transcript (Entrez)NM_025067 NM_052920
RefSeq genomic (Entrez)NC_000002 NC_018913 NT_022184 NW_004929300
Consensus coding sequences : CCDS (NCBI)KLHL29
Cluster EST : UnigeneHs.130593 [ NCBI ]
CGAP (NCI)Hs.130593
Alternative Splicing GalleryENSG00000119771
Gene ExpressionKLHL29 [ NCBI-GEO ]   KLHL29 [ EBI - ARRAY_EXPRESS ]   KLHL29 [ SEEK ]   KLHL29 [ MEM ]
Gene Expression Viewer (FireBrowse)KLHL29 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)114818
GTEX Portal (Tissue expression)KLHL29
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96CT2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96CT2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96CT2
Splice isoforms : SwissVarQ96CT2
PhosPhoSitePlusQ96CT2
Domaine pattern : Prosite (Expaxy)BTB (PS50097)   
Domains : Interpro (EBI)BACK    BTB/POZ_dom    Gal_Oxidase_b-propeller    Kelch_1    SKP1/BTB/POZ   
Domain families : Pfam (Sanger)BACK (PF07707)    BTB (PF00651)    Kelch_1 (PF01344)   
Domain families : Pfam (NCBI)pfam07707    pfam00651    pfam01344   
Domain families : Smart (EMBL)BACK (SM00875)  BTB (SM00225)  Kelch (SM00612)  
Conserved Domain (NCBI)KLHL29
DMDM Disease mutations114818
Blocks (Seattle)KLHL29
SuperfamilyQ96CT2
Human Protein AtlasENSG00000119771
Peptide AtlasQ96CT2
IPIIPI00060624   IPI00888984   
Protein Interaction databases
DIP (DOE-UCLA)Q96CT2
IntAct (EBI)Q96CT2
FunCoupENSG00000119771
BioGRIDKLHL29
STRING (EMBL)KLHL29
ZODIACKLHL29
Ontologies - Pathways
QuickGOQ96CT2
Ontology : AmiGOubiquitin-protein transferase activity  protein ubiquitination  Cul3-RING ubiquitin ligase complex  
Ontology : EGO-EBIubiquitin-protein transferase activity  protein ubiquitination  Cul3-RING ubiquitin ligase complex  
NDEx NetworkKLHL29
Atlas of Cancer Signalling NetworkKLHL29
Wikipedia pathwaysKLHL29
Orthology - Evolution
OrthoDB114818
GeneTree (enSembl)ENSG00000119771
Phylogenetic Trees/Animal Genes : TreeFamKLHL29
HOVERGENQ96CT2
HOGENOMQ96CT2
Homologs : HomoloGeneKLHL29
Homology/Alignments : Family Browser (UCSC)KLHL29
Gene fusions - Rearrangements
Fusion : MitelmanGPN1/KLHL29 [2p23.3/2p24.1]  [t(2;2)(p23;p24)]  
Fusion : MitelmanKLHL29/PSMA8 [2p24.1/18q11.2]  [t(2;18)(p24;q11)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKLHL29 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KLHL29
dbVarKLHL29
ClinVarKLHL29
1000_GenomesKLHL29 
Exome Variant ServerKLHL29
ExAC (Exome Aggregation Consortium)KLHL29 (select the gene name)
Genetic variants : HAPMAP114818
Genomic Variants (DGV)KLHL29 [DGVbeta]
DECIPHER (Syndromes)2:23608298-23931483  ENSG00000119771
CONAN: Copy Number AnalysisKLHL29 
Mutations
ICGC Data PortalKLHL29 
TCGA Data PortalKLHL29 
Broad Tumor PortalKLHL29
OASIS PortalKLHL29 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKLHL29  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKLHL29
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KLHL29
DgiDB (Drug Gene Interaction Database)KLHL29
DoCM (Curated mutations)KLHL29 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KLHL29 (select a term)
intoGenKLHL29
Cancer3DKLHL29(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenKLHL29
Genetic Testing Registry KLHL29
NextProtQ96CT2 [Medical]
TSGene114818
GENETestsKLHL29
Huge Navigator KLHL29 [HugePedia]
snp3D : Map Gene to Disease114818
BioCentury BCIQKLHL29
ClinGenKLHL29
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD114818
Chemical/Pharm GKB GenePA162393486
Clinical trialKLHL29
Miscellaneous
canSAR (ICR)KLHL29 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKLHL29
EVEXKLHL29
GoPubMedKLHL29
iHOPKLHL29
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 15:06:22 CEST 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.