Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

KLHL35 (kelch like family member 35)

Identity

Alias (NCBI)-
HGNC (Hugo) KLHL35
HGNC Alias symbFLJ33790
HGNC Previous namekelch-like 35 (Drosophila)
LocusID (NCBI) 283212
Atlas_Id 64978
Location 11q13.4  [Link to chromosome band 11q13]
Location_base_pair Starts at 75422394 and ends at 75430629 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ARRB1 (11q13.4) / KLHL35 (11q13.4)KLHL35 (11q13.4) / GDPD5 (11q13.4)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)KLHL35   26597
Cards
Entrez_Gene (NCBI)KLHL35    kelch like family member 35
Aliases
GeneCards (Weizmann)KLHL35
Ensembl hg19 (Hinxton)ENSG00000149243 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000149243 [Gene_View]  ENSG00000149243 [Sequence]  chr11:75422394-75430629 [Contig_View]  KLHL35 [Vega]
ICGC DataPortalENSG00000149243
TCGA cBioPortalKLHL35
AceView (NCBI)KLHL35
Genatlas (Paris)KLHL35
SOURCE (Princeton)KLHL35
Genetics Home Reference (NIH)KLHL35
Genomic and cartography
GoldenPath hg38 (UCSC)KLHL35  -     chr11:75422394-75430629 -  11q13.4   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KLHL35  -     11q13.4   [Description]    (hg19-Feb_2009)
GoldenPathKLHL35 - 11q13.4 [CytoView hg19]  KLHL35 - 11q13.4 [CytoView hg38]
ImmunoBaseENSG00000149243
Genome Data Viewer NCBIKLHL35 [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AK091109 AL050370 BC042952 BC057763 BC131539
RefSeq transcript (Entrez)NM_001039548 NM_173583
Consensus coding sequences : CCDS (NCBI)KLHL35
Gene ExpressionKLHL35 [ NCBI-GEO ]   KLHL35 [ EBI - ARRAY_EXPRESS ]   KLHL35 [ SEEK ]   KLHL35 [ MEM ]
Gene Expression Viewer (FireBrowse)KLHL35 [ Firebrowse - Broad ]
GenevisibleExpression of KLHL35 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)283212
GTEX Portal (Tissue expression)KLHL35
Human Protein AtlasENSG00000149243-KLHL35 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6PF15   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6PF15  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6PF15
PhosPhoSitePlusQ6PF15
Domaine pattern : Prosite (Expaxy)BTB (PS50097)   
Domains : Interpro (EBI)BACK    BTB-kelch_protein    BTB/POZ_dom    Kelch-typ_b-propeller    Kelch_1    KLHL35    SKP1/BTB/POZ_sf   
Domain families : Pfam (Sanger)BACK (PF07707)    BTB (PF00651)    Kelch_1 (PF01344)   
Domain families : Pfam (NCBI)pfam07707    pfam00651    pfam01344   
Domain families : Smart (EMBL)BACK (SM00875)  BTB (SM00225)  Kelch (SM00612)  
Conserved Domain (NCBI)KLHL35
SuperfamilyQ6PF15
AlphaFold pdb e-kbQ6PF15   
Human Protein Atlas [tissue]ENSG00000149243-KLHL35 [tissue]
HPRD08747
Protein Interaction databases
DIP (DOE-UCLA)Q6PF15
IntAct (EBI)Q6PF15
BioGRIDKLHL35
STRING (EMBL)KLHL35
ZODIACKLHL35
Ontologies - Pathways
QuickGOQ6PF15
Ontology : AmiGOprotein binding  
Ontology : EGO-EBIprotein binding  
NDEx NetworkKLHL35
Atlas of Cancer Signalling NetworkKLHL35
Wikipedia pathwaysKLHL35
Orthology - Evolution
OrthoDB283212
GeneTree (enSembl)ENSG00000149243
Phylogenetic Trees/Animal Genes : TreeFamKLHL35
Homologs : HomoloGeneKLHL35
Homology/Alignments : Family Browser (UCSC)KLHL35
Gene fusions - Rearrangements
Fusion : QuiverKLHL35
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKLHL35 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KLHL35
dbVarKLHL35
ClinVarKLHL35
MonarchKLHL35
1000_GenomesKLHL35 
Exome Variant ServerKLHL35
GNOMAD BrowserENSG00000149243
Varsome BrowserKLHL35
ACMGKLHL35 variants
VarityQ6PF15
Genomic Variants (DGV)KLHL35 [DGVbeta]
DECIPHERKLHL35 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKLHL35 
Mutations
ICGC Data PortalKLHL35 
TCGA Data PortalKLHL35 
Broad Tumor PortalKLHL35
OASIS PortalKLHL35 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKLHL35  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DKLHL35
Mutations and Diseases : HGMDKLHL35
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaKLHL35
DgiDB (Drug Gene Interaction Database)KLHL35
DoCM (Curated mutations)KLHL35
CIViC (Clinical Interpretations of Variants in Cancer)KLHL35
Cancer3DKLHL35
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETKLHL35
MedgenKLHL35
Genetic Testing Registry KLHL35
NextProtQ6PF15 [Medical]
GENETestsKLHL35
Target ValidationKLHL35
Huge Navigator KLHL35 [HugePedia]
ClinGenKLHL35
Clinical trials, drugs, therapy
MyCancerGenomeKLHL35
Protein Interactions : CTDKLHL35
Pharm GKB GenePA162393595
PharosQ6PF15
Clinical trialKLHL35
Miscellaneous
canSAR (ICR)KLHL35
HarmonizomeKLHL35
DataMed IndexKLHL35
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXKLHL35
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:54:47 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.