Atlas of Genetics and Cytogenetics in Oncology and Haematology


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KLHL35 (kelch like family member 35)

Identity

Alias_nameskelch-like 35 (Drosophila)
Alias_symbol (synonym)FLJ33790
Other alias-
HGNC (Hugo) KLHL35
LocusID (NCBI) 283212
Atlas_Id 64978
Location 11q13.4  [Link to chromosome band 11q13]
Location_base_pair Starts at 75422394 and ends at 75430629 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ARRB1 (11q13.4) / KLHL35 (11q13.4)KLHL35 (11q13.4) / GDPD5 (11q13.4)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KLHL35   26597
Cards
Entrez_Gene (NCBI)KLHL35  283212  kelch like family member 35
Aliases
GeneCards (Weizmann)KLHL35
Ensembl hg19 (Hinxton)ENSG00000149243 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000149243 [Gene_View]  chr11:75422394-75430629 [Contig_View]  KLHL35 [Vega]
ICGC DataPortalENSG00000149243
TCGA cBioPortalKLHL35
AceView (NCBI)KLHL35
Genatlas (Paris)KLHL35
WikiGenes283212
SOURCE (Princeton)KLHL35
Genetics Home Reference (NIH)KLHL35
Genomic and cartography
GoldenPath hg38 (UCSC)KLHL35  -     chr11:75422394-75430629 -  11q13.4   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KLHL35  -     11q13.4   [Description]    (hg19-Feb_2009)
EnsemblKLHL35 - 11q13.4 [CytoView hg19]  KLHL35 - 11q13.4 [CytoView hg38]
Mapping of homologs : NCBIKLHL35 [Mapview hg19]  KLHL35 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK091109 AL050370 BC042952 BC057763 BC131539
RefSeq transcript (Entrez)NM_001039548 NM_173583
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KLHL35
Cluster EST : UnigeneHs.292451 [ NCBI ]
CGAP (NCI)Hs.292451
Alternative Splicing GalleryENSG00000149243
Gene ExpressionKLHL35 [ NCBI-GEO ]   KLHL35 [ EBI - ARRAY_EXPRESS ]   KLHL35 [ SEEK ]   KLHL35 [ MEM ]
Gene Expression Viewer (FireBrowse)KLHL35 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)283212
GTEX Portal (Tissue expression)KLHL35
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6PF15   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6PF15  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6PF15
Splice isoforms : SwissVarQ6PF15
PhosPhoSitePlusQ6PF15
Domaine pattern : Prosite (Expaxy)BTB (PS50097)   
Domains : Interpro (EBI)BACK    BTB-kelch_protein    BTB/POZ_dom    Gal_Oxidase_b-propeller    Kelch_1    KLHL35    SKP1/BTB/POZ   
Domain families : Pfam (Sanger)BACK (PF07707)    BTB (PF00651)    Kelch_1 (PF01344)   
Domain families : Pfam (NCBI)pfam07707    pfam00651    pfam01344   
Domain families : Smart (EMBL)BACK (SM00875)  BTB (SM00225)  Kelch (SM00612)  
Conserved Domain (NCBI)KLHL35
DMDM Disease mutations283212
Blocks (Seattle)KLHL35
SuperfamilyQ6PF15
Human Protein AtlasENSG00000149243
Peptide AtlasQ6PF15
HPRD08747
IPIIPI00447621   IPI00744880   IPI01013641   
Protein Interaction databases
DIP (DOE-UCLA)Q6PF15
IntAct (EBI)Q6PF15
FunCoupENSG00000149243
BioGRIDKLHL35
STRING (EMBL)KLHL35
ZODIACKLHL35
Ontologies - Pathways
QuickGOQ6PF15
Ontology : AmiGOubiquitin-protein transferase activity  protein binding  protein ubiquitination  Cul3-RING ubiquitin ligase complex  
Ontology : EGO-EBIubiquitin-protein transferase activity  protein binding  protein ubiquitination  Cul3-RING ubiquitin ligase complex  
NDEx NetworkKLHL35
Atlas of Cancer Signalling NetworkKLHL35
Wikipedia pathwaysKLHL35
Orthology - Evolution
OrthoDB283212
GeneTree (enSembl)ENSG00000149243
Phylogenetic Trees/Animal Genes : TreeFamKLHL35
HOVERGENQ6PF15
HOGENOMQ6PF15
Homologs : HomoloGeneKLHL35
Homology/Alignments : Family Browser (UCSC)KLHL35
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKLHL35 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KLHL35
dbVarKLHL35
ClinVarKLHL35
1000_GenomesKLHL35 
Exome Variant ServerKLHL35
ExAC (Exome Aggregation Consortium)KLHL35 (select the gene name)
Genetic variants : HAPMAP283212
Genomic Variants (DGV)KLHL35 [DGVbeta]
DECIPHERKLHL35 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKLHL35 
Mutations
ICGC Data PortalKLHL35 
TCGA Data PortalKLHL35 
Broad Tumor PortalKLHL35
OASIS PortalKLHL35 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKLHL35  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKLHL35
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KLHL35
DgiDB (Drug Gene Interaction Database)KLHL35
DoCM (Curated mutations)KLHL35 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KLHL35 (select a term)
intoGenKLHL35
Cancer3DKLHL35(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenKLHL35
Genetic Testing Registry KLHL35
NextProtQ6PF15 [Medical]
TSGene283212
GENETestsKLHL35
Target ValidationKLHL35
Huge Navigator KLHL35 [HugePedia]
snp3D : Map Gene to Disease283212
BioCentury BCIQKLHL35
ClinGenKLHL35
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD283212
Chemical/Pharm GKB GenePA162393595
Clinical trialKLHL35
Miscellaneous
canSAR (ICR)KLHL35 (select the gene name)
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKLHL35
EVEXKLHL35
GoPubMedKLHL35
iHOPKLHL35
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 15:54:49 CEST 2017

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