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KLK12 (kallikrein-related peptidase 12)

Identity

Other namesKLK-L5
KLKL5
HGNC (Hugo) KLK12
LocusID (NCBI) 43849
Location 19q13.41
Location_base_pair Starts at 51532348 and ends at 51538148 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)KLK12   6360
Cards
Entrez_Gene (NCBI)KLK12  43849  kallikrein-related peptidase 12
GeneCards (Weizmann)KLK12
Ensembl (Hinxton)ENSG00000186474 [Gene_View]  chr19:51532348-51538148 [Contig_View]  KLK12 [Vega]
AceView (NCBI)KLK12
Genatlas (Paris)KLK12
WikiGenes43849
SOURCE (Princeton)NM_019598 NM_145894 NM_145895
Genomic and cartography
GoldenPath (UCSC)KLK12  -  19q13.41   chr19:51532348-51538148 -  19q13.41   [Description]    (hg19-Feb_2009)
EnsemblKLK12 - 19q13.41 [CytoView]
Mapping of homologs : NCBIKLK12 [Mapview]
OMIM605539   
Gene and transcription
Genbank (Entrez)AY358524 BC035385 BC136341 BC143988 BC143990
RefSeq transcript (Entrez)NM_019598 NM_145894 NM_145895
RefSeq genomic (Entrez)AC_000151 NC_000019 NC_018930 NT_011109 NW_001838498 NW_004929415
Consensus coding sequences : CCDS (NCBI)KLK12
Cluster EST : UnigeneHs.411572 [ NCBI ]
CGAP (NCI)Hs.411572
Alternative Splicing : Fast-db (Paris)GSHG0016043
Alternative Splicing GalleryENSG00000186474
Gene ExpressionKLK12 [ NCBI-GEO ]     KLK12 [ SEEK ]   KLK12 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UKR0 (Uniprot)
NextProtQ9UKR0  [Medical]
With graphics : InterProQ9UKR0
Splice isoforms : SwissVarQ9UKR0 (Swissvar)
Catalytic activity : Enzyme3.4.21.- [ Enzyme-Expasy ]   3.4.21.-3.4.21.- [ IntEnz-EBI ]   3.4.21.- [ BRENDA ]   3.4.21.- [ KEGG ]   
Domaine pattern : Prosite (Expaxy)TRYPSIN_DOM (PS50240)    TRYPSIN_HIS (PS00134)    TRYPSIN_SER (PS00135)   
Domains : Interpro (EBI)Peptidase_S1    Peptidase_S1_AS    Peptidase_S1A    Trypsin-like_Pept_dom   
Related proteins : CluSTrQ9UKR0
Domain families : Pfam (Sanger)Trypsin (PF00089)   
Domain families : Pfam (NCBI)pfam00089   
Domain families : Smart (EMBL)Tryp_SPc (SM00020)  
DMDM Disease mutations43849
Blocks (Seattle)Q9UKR0
Human Protein AtlasENSG00000186474
Peptide AtlasQ9UKR0
HPRD05705
IPIIPI00007724   IPI00220155   IPI00941336   IPI00395677   IPI00983268   IPI00985039   IPI00010516   
Protein Interaction databases
DIP (DOE-UCLA)Q9UKR0
IntAct (EBI)Q9UKR0
FunCoupENSG00000186474
BioGRIDKLK12
InParanoidQ9UKR0
Interologous Interaction database Q9UKR0
IntegromeDBKLK12
STRING (EMBL)KLK12
Ontologies - Pathways
Ontology : AmiGOserine-type endopeptidase activity  extracellular region  extracellular space  proteolysis  proteolysis  peptidase activity  serine-type peptidase activity  
Ontology : EGO-EBIserine-type endopeptidase activity  extracellular region  extracellular space  proteolysis  proteolysis  peptidase activity  serine-type peptidase activity  
REACTOMEKLK12
Protein Interaction DatabaseKLK12
Wikipedia pathwaysKLK12
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)KLK12
SNP (GeneSNP Utah)KLK12
SNP : HGBaseKLK12
Genetic variants : HAPMAPKLK12
1000_GenomesKLK12 
ICGC programENSG00000186474 
Somatic Mutations in Cancer : COSMICKLK12 
CONAN: Copy Number AnalysisKLK12 
Mutations and Diseases : HGMDKLK12
OMIM605539   
GENETestsKLK12
Disease Genetic AssociationKLK12
Huge Navigator KLK12 [HugePedia]  KLK12 [HugeCancerGEM]
Genomic VariantsKLK12  KLK12 [DGVbeta]
Exome VariantKLK12
dbVarKLK12
ClinVarKLK12
snp3D : Map Gene to Disease43849
General knowledge
Homologs : HomoloGeneKLK12
Homology/Alignments : Family Browser (UCSC)KLK12
Phylogenetic Trees/Animal Genes : TreeFamKLK12
Chemical/Protein Interactions : CTD43849
Chemical/Pharm GKB GenePA30149
Clinical trialKLK12
Cancer Resource (Charite)ENSG00000186474
Other databases
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
CoreMineKLK12
iHOPKLK12
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Apr 18 16:47:51 CEST 2014

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