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KLK12 (kallikrein-related peptidase 12)

Identity

Other namesKLK-L5
KLKL5
HGNC (Hugo) KLK12
LocusID (NCBI) 43849
Location 19q13.41
Location_base_pair Starts at 51532348 and ends at 51538148 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)KLK12   6360
Entrez_Gene (NCBI)KLK12  43849  kallikrein-related peptidase 12
Cards
GeneCards (Weizmann)KLK12
Ensembl (Hinxton)ENSG00000186474 [Gene_View]  chr19:51532348-51538148 [Contig_View]  KLK12 [Vega]
AceView (NCBI)KLK12
Genatlas (Paris)KLK12
SOURCE (Stanford)NM_019598 NM_145894 NM_145895
Genomic and cartography
GoldenPath (UCSC)KLK12  -  19q13.41   chr19:51532348-51538148 -  19q13.41   [Description]    (hg19-Feb_2009)
EnsemblKLK12 - 19q13.41 [CytoView]
Mapping of homologs : NCBIKLK12 [Mapview]
OMIM605539   
Gene and transcription
Genbank (Entrez)AY358524 BC035385 BC136341 BC143988 BC143990
RefSeq transcript (SRS)NM_019598 NM_145894 NM_145895
RefSeq transcript (Entrez)NM_019598 NM_145894 NM_145895
RefSeq genomic (SRS)AC_000151 NC_000019 NC_018930 NT_011109 NW_001838498 NW_004078099
RefSeq genomic (Entrez)AC_000151 NC_000019 NC_018930 NT_011109 NW_001838498 NW_004078099
Consensus coding sequences : CCDS (NCBI)KLK12
Cluster EST : UnigeneHs.411572 [ SRS ] Hs.411572 [ NCBI ]
CGAP (NCI)Hs.411572
Alternative Splicing : Fast-db (Paris)GSHG0016043
Alternative Splicing GalleryENSG00000186474
Gene ExpressionKLK12 [ NCBI-GEO ]   KLK12 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UKR0 (SRS) Q9UKR0 (Uniprot)
NextProtQ9UKR0
With graphics : InterProQ9UKR0
Splice isoforms : SwissVarQ9UKR0(Swissvar)
Domaine pattern : Prosite (SRS)TRYPSIN_DOM (PS50240)    TRYPSIN_HIS (PS00134)    TRYPSIN_SER (PS00135)   
Domaine pattern : Prosite (Expaxy)TRYPSIN_DOM (PS50240)    TRYPSIN_HIS (PS00134)    TRYPSIN_SER (PS00135)   
Domains : Interpro (SRS)Pept_cys/ser_Trypsin-like    Peptidase_S1/S6_AS    Peptidase_S1_S6    Peptidase_S1A   
Domains : Interpro (EBI)Pept_cys/ser_Trypsin-like    Peptidase_S1/S6_AS    Peptidase_S1_S6    Peptidase_S1A   
Related proteins : CluSTrQ9UKR0
Domain families : Pfam (SRS)Trypsin (PF00089)   
Domain families : Pfam (Sanger)Trypsin (PF00089)   
Domain families : Pfam (NCBI)pfam00089   
Domain families : Smart (EMBL)Tryp_SPc (SM00020)  
DMDM43849
Blocks (Seattle)Q9UKR0
Human Protein AtlasENSG00000186474
HPRD05705
IPIIPI00007724   IPI00220155   IPI00941336   IPI00395677   IPI00983268   IPI00985039   IPI00010516   
Protein Interaction databases
DIP (DOE-UCLA)Q9UKR0
IntAct (EBI)Q9UKR0
FunCoupENSG00000186474
REACTOMEKLK12
Protein Interaction Database43849
BioGRIDKLK12
InParanoidQ9UKR0
Interologous Interaction database Q9UKR0
IntegromeDBKLK12
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)KLK12
SNP (GeneSNP Utah)KLK12
SNP : HGBaseKLK12
Genetic variants : HAPMAPKLK12
Somatic Mutations in Cancer : COSMICKLK12 
CONAN: Copy Number AnalysisKLK12 
Mutations and Diseases : HGMDKLK12
OMIM605539   
GENETests605539   
Disease Genetic AssociationKLK12
Huge Navigator KLK12 [HugePedia]  KLK12 [HugeCancerGEM]
Genomic VariantsKLK12  KLK12 [DGVbeta]
snp3D : Map Gene to Disease43849
General knowledge
Homologs : HomoloGeneKLK12
Homology/Alignments : Family Browser (UCSC)KLK12
Phylogenetic Trees/Animal Genes : TreeFamKLK12
Catalytic activity : Enzyme3.4.21.- [ Enzyme-Expasy ]   3.4.21.- [ Enzyme-SRS ]   3.4.21.- [ IntEnz-EBI ]   3.4.21.- [ BRENDA ]   3.4.21.- [ KEGG ]   
Chemical/Protein Interactions : CTD43849
Chemical/Pharm GKB GenePA30149
Clinical trialKLK12
Cancer Resource (Charite)ENSG00000186474
Ontology : AmiGOserine-type endopeptidase activity  extracellular region  extracellular space  proteolysis  proteolysis  peptidase activity  serine-type peptidase activity  
Ontology : EGO-EBIserine-type endopeptidase activity  extracellular region  extracellular space  proteolysis  proteolysis  peptidase activity  serine-type peptidase activity  
Other databases
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
PubGeneKLK12
iHOPKLK12
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:23:19 CEST 2013
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