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KLK14 (kallikrein related peptidase 14)

Identity

Other namesKLK-L6
HGNC (Hugo) KLK14
LocusID (NCBI) 43847
Atlas_Id 41080
Location 19q13.41
Location_base_pair Starts at 51580752 and ends at 51587467 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KLK14   6362
Cards
Entrez_Gene (NCBI)KLK14  43847  kallikrein related peptidase 14
AliasesKLK-L6
GeneCards (Weizmann)KLK14
Ensembl hg19 (Hinxton)ENSG00000129437 [Gene_View]  chr19:51580752-51587467 [Contig_View]  KLK14 [Vega]
Ensembl hg38 (Hinxton)ENSG00000129437 [Gene_View]  chr19:51580752-51587467 [Contig_View]  KLK14 [Vega]
ICGC DataPortalENSG00000129437
TCGA cBioPortalKLK14
AceView (NCBI)KLK14
Genatlas (Paris)KLK14
WikiGenes43847
SOURCE (Princeton)KLK14
Genomic and cartography
GoldenPath hg19 (UCSC)KLK14  -     chr19:51580752-51587467 -  19q13.41   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)KLK14  -     19q13.41   [Description]    (hg38-Dec_2013)
EnsemblKLK14 - 19q13.41 [CytoView hg19]  KLK14 - 19q13.41 [CytoView hg38]
Mapping of homologs : NCBIKLK14 [Mapview hg19]  KLK14 [Mapview hg38]
OMIM606135   
Gene and transcription
Genbank (Entrez)AF283670 BC074904 BC074905 BC114614
RefSeq transcript (Entrez)NM_001311182 NM_022046
RefSeq genomic (Entrez)NC_000019 NC_018930 NT_011109 NW_004929415
Consensus coding sequences : CCDS (NCBI)KLK14
Cluster EST : UnigeneHs.283925 [ NCBI ]
CGAP (NCI)Hs.283925
Alternative Splicing GalleryENSG00000129437
Gene ExpressionKLK14 [ NCBI-GEO ]   KLK14 [ EBI - ARRAY_EXPRESS ]   KLK14 [ SEEK ]   KLK14 [ MEM ]
Gene Expression Viewer (FireBrowse)KLK14 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)43847
GTEX Portal (Tissue expression)KLK14
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9P0G3 (Uniprot)
NextProtQ9P0G3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9P0G3
Splice isoforms : SwissVarQ9P0G3 (Swissvar)
Catalytic activity : Enzyme3.4.21.- [ Enzyme-Expasy ]   3.4.21.-3.4.21.- [ IntEnz-EBI ]   3.4.21.- [ BRENDA ]   3.4.21.- [ KEGG ]   
PhosPhoSitePlusQ9P0G3
Domaine pattern : Prosite (Expaxy)TRYPSIN_DOM (PS50240)    TRYPSIN_HIS (PS00134)    TRYPSIN_SER (PS00135)   
Domains : Interpro (EBI)Peptidase_S1_PA    Peptidase_S1A    Trypsin_dom    TRYPSIN_HIS    TRYPSIN_SER   
Domain families : Pfam (Sanger)Trypsin (PF00089)   
Domain families : Pfam (NCBI)pfam00089   
Domain families : Smart (EMBL)Tryp_SPc (SM00020)  
DMDM Disease mutations43847
Blocks (Seattle)KLK14
SuperfamilyQ9P0G3
Human Protein AtlasENSG00000129437
Peptide AtlasQ9P0G3
HPRD05844
IPIIPI00000700   
Protein Interaction databases
DIP (DOE-UCLA)Q9P0G3
IntAct (EBI)Q9P0G3
FunCoupENSG00000129437
BioGRIDKLK14
STRING (EMBL)KLK14
ZODIACKLK14
Ontologies - Pathways
QuickGOQ9P0G3
Ontology : AmiGOserine-type endopeptidase activity  serine-type endopeptidase activity  extracellular space  proteolysis  fertilization  negative regulation of G-protein coupled receptor protein signaling pathway  positive regulation of G-protein coupled receptor protein signaling pathway  epidermis morphogenesis  extracellular exosome  seminal clot liquefaction  
Ontology : EGO-EBIserine-type endopeptidase activity  serine-type endopeptidase activity  extracellular space  proteolysis  fertilization  negative regulation of G-protein coupled receptor protein signaling pathway  positive regulation of G-protein coupled receptor protein signaling pathway  epidermis morphogenesis  extracellular exosome  seminal clot liquefaction  
NDEx Network
Atlas of Cancer Signalling NetworkKLK14
Wikipedia pathwaysKLK14
Orthology - Evolution
OrthoDB43847
GeneTree (enSembl)ENSG00000129437
Phylogenetic Trees/Animal Genes : TreeFamKLK14
Homologs : HomoloGeneKLK14
Homology/Alignments : Family Browser (UCSC)KLK14
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerKLK14 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KLK14
dbVarKLK14
ClinVarKLK14
1000_GenomesKLK14 
Exome Variant ServerKLK14
ExAC (Exome Aggregation Consortium)KLK14 (select the gene name)
Genetic variants : HAPMAP43847
Genomic Variants (DGV)KLK14 [DGVbeta]
Mutations
ICGC Data PortalKLK14 
TCGA Data PortalKLK14 
Broad Tumor PortalKLK14
OASIS PortalKLK14 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKLK14 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KLK14
DgiDB (Drug Gene Interaction Database)KLK14
DoCM (Curated mutations)KLK14 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KLK14 (select a term)
intoGenKLK14
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)19:51580752-51587467  ENSG00000129437
CONAN: Copy Number AnalysisKLK14 
Mutations and Diseases : HGMDKLK14
OMIM606135   
MedgenKLK14
Genetic Testing Registry KLK14
NextProtQ9P0G3 [Medical]
TSGene43847
GENETestsKLK14
Huge Navigator KLK14 [HugePedia]
snp3D : Map Gene to Disease43847
BioCentury BCIQKLK14
ClinGenKLK14
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD43847
Chemical/Pharm GKB GenePA30151
Clinical trialKLK14
Miscellaneous
canSAR (ICR)KLK14 (select the gene name)
Probes
Litterature
PubMed33 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKLK14
EVEXKLK14
GoPubMedKLK14
iHOPKLK14
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat May 28 11:08:08 CEST 2016

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