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KLK15 (kallikrein related peptidase 15)

Identity

Alias_nameskallikrein 15
Alias_symbol (synonym)HSRNASPH
ACO
prostinogen
Other alias
HGNC (Hugo) KLK15
LocusID (NCBI) 55554
Atlas_Id 41081
Location 19q13.33  [Link to chromosome band 19q13]
Location_base_pair Starts at 50825289 and ends at 50831523 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KLK15   20453
Cards
Entrez_Gene (NCBI)KLK15  55554  kallikrein related peptidase 15
AliasesACO; HSRNASPH
GeneCards (Weizmann)KLK15
Ensembl hg19 (Hinxton)ENSG00000174562 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000174562 [Gene_View]  chr19:50825289-50831523 [Contig_View]  KLK15 [Vega]
ICGC DataPortalENSG00000174562
TCGA cBioPortalKLK15
AceView (NCBI)KLK15
Genatlas (Paris)KLK15
WikiGenes55554
SOURCE (Princeton)KLK15
Genetics Home Reference (NIH)KLK15
Genomic and cartography
GoldenPath hg38 (UCSC)KLK15  -     chr19:50825289-50831523 -  19q13.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KLK15  -     19q13.33   [Description]    (hg19-Feb_2009)
EnsemblKLK15 - 19q13.33 [CytoView hg19]  KLK15 - 19q13.33 [CytoView hg38]
Mapping of homologs : NCBIKLK15 [Mapview hg19]  KLK15 [Mapview hg38]
OMIM610601   
Gene and transcription
Genbank (Entrez)AF303046 AW205420 AY373373 AY373374 BC069480
RefSeq transcript (Entrez)NM_001277081 NM_001277082 NM_017509 NM_023006 NM_138563 NM_138564
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KLK15
Cluster EST : UnigeneHs.567535 [ NCBI ]
CGAP (NCI)Hs.567535
Alternative Splicing GalleryENSG00000174562
Gene ExpressionKLK15 [ NCBI-GEO ]   KLK15 [ EBI - ARRAY_EXPRESS ]   KLK15 [ SEEK ]   KLK15 [ MEM ]
Gene Expression Viewer (FireBrowse)KLK15 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55554
GTEX Portal (Tissue expression)KLK15
Human Protein AtlasENSG00000174562-KLK15 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H2R5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H2R5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H2R5
Splice isoforms : SwissVarQ9H2R5
Catalytic activity : Enzyme3.4.21.- [ Enzyme-Expasy ]   3.4.21.-3.4.21.- [ IntEnz-EBI ]   3.4.21.- [ BRENDA ]   3.4.21.- [ KEGG ]   
PhosPhoSitePlusQ9H2R5
Domaine pattern : Prosite (Expaxy)TRYPSIN_DOM (PS50240)    TRYPSIN_HIS (PS00134)   
Domains : Interpro (EBI)Peptidase_S1_PA    Peptidase_S1A    Trypsin_dom    TRYPSIN_HIS   
Domain families : Pfam (Sanger)Trypsin (PF00089)   
Domain families : Pfam (NCBI)pfam00089   
Domain families : Smart (EMBL)Tryp_SPc (SM00020)  
Conserved Domain (NCBI)KLK15
DMDM Disease mutations55554
Blocks (Seattle)KLK15
SuperfamilyQ9H2R5
Human Protein Atlas [tissue]ENSG00000174562-KLK15 [tissue]
Peptide AtlasQ9H2R5
HPRD07490
IPIIPI00033970   IPI00150552   IPI00219692   IPI00219693   IPI01011660   
Protein Interaction databases
DIP (DOE-UCLA)Q9H2R5
IntAct (EBI)Q9H2R5
FunCoupENSG00000174562
BioGRIDKLK15
STRING (EMBL)KLK15
ZODIACKLK15
Ontologies - Pathways
QuickGOQ9H2R5
Ontology : AmiGOserine-type endopeptidase activity  protein binding  extracellular region  proteolysis  serine-type peptidase activity  
Ontology : EGO-EBIserine-type endopeptidase activity  protein binding  extracellular region  proteolysis  serine-type peptidase activity  
NDEx NetworkKLK15
Atlas of Cancer Signalling NetworkKLK15
Wikipedia pathwaysKLK15
Orthology - Evolution
OrthoDB55554
GeneTree (enSembl)ENSG00000174562
Phylogenetic Trees/Animal Genes : TreeFamKLK15
HOVERGENQ9H2R5
HOGENOMQ9H2R5
Homologs : HomoloGeneKLK15
Homology/Alignments : Family Browser (UCSC)KLK15
Gene fusions - Rearrangements
Tumor Fusion PortalKLK15
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKLK15 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KLK15
dbVarKLK15
ClinVarKLK15
1000_GenomesKLK15 
Exome Variant ServerKLK15
ExAC (Exome Aggregation Consortium)ENSG00000174562
GNOMAD BrowserENSG00000174562
Genetic variants : HAPMAP55554
Genomic Variants (DGV)KLK15 [DGVbeta]
DECIPHERKLK15 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKLK15 
Mutations
ICGC Data PortalKLK15 
TCGA Data PortalKLK15 
Broad Tumor PortalKLK15
OASIS PortalKLK15 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKLK15  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKLK15
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KLK15
DgiDB (Drug Gene Interaction Database)KLK15
DoCM (Curated mutations)KLK15 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KLK15 (select a term)
intoGenKLK15
Cancer3DKLK15(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610601   
Orphanet
DisGeNETKLK15
MedgenKLK15
Genetic Testing Registry KLK15
NextProtQ9H2R5 [Medical]
TSGene55554
GENETestsKLK15
Target ValidationKLK15
Huge Navigator KLK15 [HugePedia]
snp3D : Map Gene to Disease55554
BioCentury BCIQKLK15
ClinGenKLK15
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55554
Chemical/Pharm GKB GenePA134977502
Clinical trialKLK15
Miscellaneous
canSAR (ICR)KLK15 (select the gene name)
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKLK15
EVEXKLK15
GoPubMedKLK15
iHOPKLK15
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:19:09 CET 2017

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