Identity
HGNC
LOCATION
12p13.31
LOCUSID
ALIAS
CD161,CLEC5B,NKR,NKR-P1,NKR-P1A,NKRP1A,hNKR-P1A
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3820
MIM: 602890
HGNC: 6373
Ensembl: ENSG00000111796
Variants:
dbSNP: 3820
ClinVar: 3820
TCGA: ENSG00000111796
COSMIC: KLRB1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000111796 | ENST00000229402 | Q12918 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38502058 | 2024 | Immune checkpoint CD161/LLT1-associated immunological landscape and diagnostic value in oral squamous cell carcinoma. | 1 |
| 38608099 | 2024 | A comprehensive analysis of the KLRB1 expression and its clinical implication in testicular germ cell tumors: A review. | 0 |
| 38636371 | 2024 | KLRB1 defines an activated phenotype of CD4+ T cells and shows significant upregulation in patients with primary Sjögren's syndrome. | 1 |
| 38782996 | 2024 | Down-regulation of KLRB1 is associated with increased cell growth, metastasis, poor prognosis, as well as a dysfunctional immune microenvironment in LUAD. | 0 |
| 38914941 | 2024 | Deciphering the role of KLRB1: a novel prognostic indicator in hepatocellular carcinoma. | 0 |
| 38502058 | 2024 | Immune checkpoint CD161/LLT1-associated immunological landscape and diagnostic value in oral squamous cell carcinoma. | 1 |
| 38608099 | 2024 | A comprehensive analysis of the KLRB1 expression and its clinical implication in testicular germ cell tumors: A review. | 0 |
| 38636371 | 2024 | KLRB1 defines an activated phenotype of CD4+ T cells and shows significant upregulation in patients with primary Sjögren's syndrome. | 1 |
| 38782996 | 2024 | Down-regulation of KLRB1 is associated with increased cell growth, metastasis, poor prognosis, as well as a dysfunctional immune microenvironment in LUAD. | 0 |
| 38914941 | 2024 | Deciphering the role of KLRB1: a novel prognostic indicator in hepatocellular carcinoma. | 0 |
| 36633583 | 2023 | CD161 Characterizes an Inflamed Subset of Cytotoxic T Lymphocytes Associated with Prolonged Survival in Human Papillomavirus-Driven Oropharyngeal Cancer. | 5 |
| 37287972 | 2023 | SARS-CoV-2 infection impairs NK cell functions via activation of the LLT1-CD161 axis. | 9 |
| 37551093 | 2023 | Eosinophilic allergic rhinitis is strongly associated with the CD45RB(lo) subset of CD161(+) Th2 cells that secretes IL-2, IL-3, IL-4, IL-5, IL-9, and IL-13. | 3 |
| 37988189 | 2023 | Inhibiting KLRB1 expression is associated with impairing cancer immunity and leading to cancer progression and poor prognosis in breast invasive carcinoma patients. | 3 |
| 36633583 | 2023 | CD161 Characterizes an Inflamed Subset of Cytotoxic T Lymphocytes Associated with Prolonged Survival in Human Papillomavirus-Driven Oropharyngeal Cancer. | 5 |
Citation
Dessen P
KLRB1 (killer cell lectin like receptor B1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/50012/klrb1
