Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

KLRB1 (killer cell lectin like receptor B1)

Identity

Alias_namesNKR
killer cell lectin-like receptor subfamily B
Alias_symbol (synonym)CD161
NKR-P1
NKR-P1A
hNKR-P1A
CLEC5B
Other aliasNKRP1A
HGNC (Hugo) KLRB1
LocusID (NCBI) 3820
Atlas_Id 50012
Location 12p13.31  [Link to chromosome band 12p13]
Location_base_pair Starts at 9747870 and ends at 9760497 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KLRB1   6373
Cards
Entrez_Gene (NCBI)KLRB1  3820  killer cell lectin like receptor B1
AliasesCD161; CLEC5B; NKR; NKR-P1; 
NKR-P1A; NKRP1A; hNKR-P1A
GeneCards (Weizmann)KLRB1
Ensembl hg19 (Hinxton)ENSG00000111796 [Gene_View]  chr12:9747870-9760497 [Contig_View]  KLRB1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000111796 [Gene_View]  chr12:9747870-9760497 [Contig_View]  KLRB1 [Vega]
ICGC DataPortalENSG00000111796
TCGA cBioPortalKLRB1
AceView (NCBI)KLRB1
Genatlas (Paris)KLRB1
WikiGenes3820
SOURCE (Princeton)KLRB1
Genetics Home Reference (NIH)KLRB1
Genomic and cartography
GoldenPath hg19 (UCSC)KLRB1  -     chr12:9747870-9760497 -  12p13.31   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)KLRB1  -     12p13.31   [Description]    (hg38-Dec_2013)
EnsemblKLRB1 - 12p13.31 [CytoView hg19]  KLRB1 - 12p13.31 [CytoView hg38]
Mapping of homologs : NCBIKLRB1 [Mapview hg19]  KLRB1 [Mapview hg38]
OMIM602890   
Gene and transcription
Genbank (Entrez)AK292022 BC027885 BC113997 BC114516 BF432813
RefSeq transcript (Entrez)NM_002258
RefSeq genomic (Entrez)NC_000012 NC_018923 NT_009714 NW_004929383
Consensus coding sequences : CCDS (NCBI)KLRB1
Cluster EST : UnigeneHs.169824 [ NCBI ]
CGAP (NCI)Hs.169824
Alternative Splicing GalleryENSG00000111796
Gene ExpressionKLRB1 [ NCBI-GEO ]   KLRB1 [ EBI - ARRAY_EXPRESS ]   KLRB1 [ SEEK ]   KLRB1 [ MEM ]
Gene Expression Viewer (FireBrowse)KLRB1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3820
GTEX Portal (Tissue expression)KLRB1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ12918   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ12918  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ12918
Splice isoforms : SwissVarQ12918
PhosPhoSitePlusQ12918
Domaine pattern : Prosite (Expaxy)C_TYPE_LECTIN_2 (PS50041)   
Domains : Interpro (EBI)C-type_lectin    C-type_lectin-like    C-type_lectin_fold   
Domain families : Pfam (Sanger)Lectin_C (PF00059)   
Domain families : Pfam (NCBI)pfam00059   
Domain families : Smart (EMBL)CLECT (SM00034)  
Conserved Domain (NCBI)KLRB1
DMDM Disease mutations3820
Blocks (Seattle)KLRB1
SuperfamilyQ12918
Human Protein AtlasENSG00000111796
Peptide AtlasQ12918
HPRD04201
IPIIPI00032471   
Protein Interaction databases
DIP (DOE-UCLA)Q12918
IntAct (EBI)Q12918
FunCoupENSG00000111796
BioGRIDKLRB1
STRING (EMBL)KLRB1
ZODIACKLRB1
Ontologies - Pathways
QuickGOQ12918
Ontology : AmiGOtransmembrane signaling receptor activity  plasma membrane  cell surface receptor signaling pathway  integral component of membrane  carbohydrate binding  regulation of immune response  
Ontology : EGO-EBItransmembrane signaling receptor activity  plasma membrane  cell surface receptor signaling pathway  integral component of membrane  carbohydrate binding  regulation of immune response  
Pathways : KEGGMalaria   
NDEx NetworkKLRB1
Atlas of Cancer Signalling NetworkKLRB1
Wikipedia pathwaysKLRB1
Orthology - Evolution
OrthoDB3820
GeneTree (enSembl)ENSG00000111796
Phylogenetic Trees/Animal Genes : TreeFamKLRB1
HOVERGENQ12918
HOGENOMQ12918
Homologs : HomoloGeneKLRB1
Homology/Alignments : Family Browser (UCSC)KLRB1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKLRB1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KLRB1
dbVarKLRB1
ClinVarKLRB1
1000_GenomesKLRB1 
Exome Variant ServerKLRB1
ExAC (Exome Aggregation Consortium)KLRB1 (select the gene name)
Genetic variants : HAPMAP3820
Genomic Variants (DGV)KLRB1 [DGVbeta]
DECIPHER (Syndromes)12:9747870-9760497  ENSG00000111796
CONAN: Copy Number AnalysisKLRB1 
Mutations
ICGC Data PortalKLRB1 
TCGA Data PortalKLRB1 
Broad Tumor PortalKLRB1
OASIS PortalKLRB1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKLRB1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKLRB1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KLRB1
DgiDB (Drug Gene Interaction Database)KLRB1
DoCM (Curated mutations)KLRB1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KLRB1 (select a term)
intoGenKLRB1
Cancer3DKLRB1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602890   
Orphanet
MedgenKLRB1
Genetic Testing Registry KLRB1
NextProtQ12918 [Medical]
TSGene3820
GENETestsKLRB1
Huge Navigator KLRB1 [HugePedia]
snp3D : Map Gene to Disease3820
BioCentury BCIQKLRB1
ClinGenKLRB1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3820
Chemical/Pharm GKB GenePA30162
Clinical trialKLRB1
Miscellaneous
canSAR (ICR)KLRB1 (select the gene name)
Probes
Litterature
PubMed47 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKLRB1
EVEXKLRB1
GoPubMedKLRB1
iHOPKLRB1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 15:06:24 CEST 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.