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KLRC2 (killer cell lectin like receptor C2)

Identity

Alias_nameskiller cell lectin-like receptor subfamily C
Alias_symbol (synonym)NKG2-C
CD159c
Other aliasNKG2C
HGNC (Hugo) KLRC2
LocusID (NCBI) 3822
Atlas_Id 41091
Location 12p13.2  [Link to chromosome band 12p13]
Location_base_pair Starts at 10583206 and ends at 10588592 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KLRC2   6375
Cards
Entrez_Gene (NCBI)KLRC2  3822  killer cell lectin like receptor C2
AliasesCD159c; NKG2-C; NKG2C
GeneCards (Weizmann)KLRC2
Ensembl hg19 (Hinxton)ENSG00000205809 [Gene_View]  chr12:10583206-10588592 [Contig_View]  KLRC2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000205809 [Gene_View]  chr12:10583206-10588592 [Contig_View]  KLRC2 [Vega]
ICGC DataPortalENSG00000205809
TCGA cBioPortalKLRC2
AceView (NCBI)KLRC2
Genatlas (Paris)KLRC2
WikiGenes3822
SOURCE (Princeton)KLRC2
Genetics Home Reference (NIH)KLRC2
Genomic and cartography
GoldenPath hg19 (UCSC)KLRC2  -     chr12:10583206-10588592 -  12p13.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)KLRC2  -     12p13.2   [Description]    (hg38-Dec_2013)
EnsemblKLRC2 - 12p13.2 [CytoView hg19]  KLRC2 - 12p13.2 [CytoView hg38]
Mapping of homologs : NCBIKLRC2 [Mapview hg19]  KLRC2 [Mapview hg38]
OMIM602891   
Gene and transcription
Genbank (Entrez)AF260134 AK295525 BC093644 BC106069 BC112039
RefSeq transcript (Entrez)NM_002260
RefSeq genomic (Entrez)NC_000012 NC_018923 NT_009714 NW_004929383
Consensus coding sequences : CCDS (NCBI)KLRC2
Cluster EST : UnigeneHs.591157 [ NCBI ]
CGAP (NCI)Hs.591157
Alternative Splicing GalleryENSG00000205809
Gene ExpressionKLRC2 [ NCBI-GEO ]   KLRC2 [ EBI - ARRAY_EXPRESS ]   KLRC2 [ SEEK ]   KLRC2 [ MEM ]
Gene Expression Viewer (FireBrowse)KLRC2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3822
GTEX Portal (Tissue expression)KLRC2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP26717   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP26717  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP26717
Splice isoforms : SwissVarP26717
PhosPhoSitePlusP26717
Domaine pattern : Prosite (Expaxy)C_TYPE_LECTIN_2 (PS50041)   
Domains : Interpro (EBI)C-type_lectin    C-type_lectin-like    C-type_lectin_fold   
Domain families : Pfam (Sanger)Lectin_C (PF00059)   
Domain families : Pfam (NCBI)pfam00059   
Domain families : Smart (EMBL)CLECT (SM00034)  
Conserved Domain (NCBI)KLRC2
DMDM Disease mutations3822
Blocks (Seattle)KLRC2
PDB (SRS)2L35   
PDB (PDBSum)2L35   
PDB (IMB)2L35   
PDB (RSDB)2L35   
Structural Biology KnowledgeBase2L35   
SCOP (Structural Classification of Proteins)2L35   
CATH (Classification of proteins structures)2L35   
SuperfamilyP26717
Human Protein AtlasENSG00000205809
Peptide AtlasP26717
HPRD04202
IPIIPI00291660   IPI00746231   IPI00872005   IPI01013216   IPI01012852   
Protein Interaction databases
DIP (DOE-UCLA)P26717
IntAct (EBI)P26717
FunCoupENSG00000205809
BioGRIDKLRC2
STRING (EMBL)KLRC2
ZODIACKLRC2
Ontologies - Pathways
QuickGOP26717
Ontology : AmiGOnatural killer cell mediated immunity  transmembrane signaling receptor activity  protein binding  plasma membrane  integral component of plasma membrane  cellular defense response  signal transduction  MHC class I protein complex binding  carbohydrate binding  receptor complex  innate immune response  protein antigen binding  
Ontology : EGO-EBInatural killer cell mediated immunity  transmembrane signaling receptor activity  protein binding  plasma membrane  integral component of plasma membrane  cellular defense response  signal transduction  MHC class I protein complex binding  carbohydrate binding  receptor complex  innate immune response  protein antigen binding  
Pathways : BIOCARTARas-Independent pathway in NK cell-mediated cytotoxicity [Genes]   
Pathways : KEGGAntigen processing and presentation    Natural killer cell mediated cytotoxicity   
NDEx NetworkKLRC2
Atlas of Cancer Signalling NetworkKLRC2
Wikipedia pathwaysKLRC2
Orthology - Evolution
OrthoDB3822
GeneTree (enSembl)ENSG00000205809
Phylogenetic Trees/Animal Genes : TreeFamKLRC2
HOVERGENP26717
HOGENOMP26717
Homologs : HomoloGeneKLRC2
Homology/Alignments : Family Browser (UCSC)KLRC2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKLRC2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KLRC2
dbVarKLRC2
ClinVarKLRC2
1000_GenomesKLRC2 
Exome Variant ServerKLRC2
ExAC (Exome Aggregation Consortium)KLRC2 (select the gene name)
Genetic variants : HAPMAP3822
Genomic Variants (DGV)KLRC2 [DGVbeta]
DECIPHER (Syndromes)12:10583206-10588592  ENSG00000205809
CONAN: Copy Number AnalysisKLRC2 
Mutations
ICGC Data PortalKLRC2 
TCGA Data PortalKLRC2 
Broad Tumor PortalKLRC2
OASIS PortalKLRC2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKLRC2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKLRC2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KLRC2
DgiDB (Drug Gene Interaction Database)KLRC2
DoCM (Curated mutations)KLRC2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KLRC2 (select a term)
intoGenKLRC2
Cancer3DKLRC2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602891   
Orphanet
MedgenKLRC2
Genetic Testing Registry KLRC2
NextProtP26717 [Medical]
TSGene3822
GENETestsKLRC2
Huge Navigator KLRC2 [HugePedia]
snp3D : Map Gene to Disease3822
BioCentury BCIQKLRC2
ClinGenKLRC2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3822
Chemical/Pharm GKB GenePA30164
Clinical trialKLRC2
Miscellaneous
canSAR (ICR)KLRC2 (select the gene name)
Probes
Litterature
PubMed43 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKLRC2
EVEXKLRC2
GoPubMedKLRC2
iHOPKLRC2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:06:25 CEST 2017

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