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KLRC4-KLRK1 (KLRC4-KLRK1 readthrough)

Identity

Other alias-
HGNC (Hugo) KLRC4-KLRK1
LocusID (NCBI) 100528032
Atlas_Id 55588
Location 12p13.2  [Link to chromosome band 12p13]
Location_base_pair Starts at 10372353 and ends at 10410146 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KLRC4-KLRK1   48357
Cards
Entrez_Gene (NCBI)KLRC4-KLRK1  100528032  KLRC4-KLRK1 readthrough
Aliases
GeneCards (Weizmann)KLRC4-KLRK1
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr12:10372353-10410146 [Contig_View]  KLRC4-KLRK1 [Vega]
TCGA cBioPortalKLRC4-KLRK1
AceView (NCBI)KLRC4-KLRK1
Genatlas (Paris)KLRC4-KLRK1
WikiGenes100528032
SOURCE (Princeton)KLRC4-KLRK1
Genetics Home Reference (NIH)KLRC4-KLRK1
Genomic and cartography
GoldenPath hg38 (UCSC)KLRC4-KLRK1  -     chr12:10372353-10410146 -  12p13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KLRC4-KLRK1  -     12p13.2   [Description]    (hg19-Feb_2009)
EnsemblKLRC4-KLRK1 - 12p13.2 [CytoView hg19]  KLRC4-KLRK1 - 12p13.2 [CytoView hg38]
Mapping of homologs : NCBIKLRC4-KLRK1 [Mapview hg19]  KLRC4-KLRK1 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF439512 AF461811 AK292020 AK310717 X54870
RefSeq transcript (Entrez)NM_001199805
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KLRC4-KLRK1
Cluster EST : UnigeneHs.387787 [ NCBI ]
CGAP (NCI)Hs.387787
Gene ExpressionKLRC4-KLRK1 [ NCBI-GEO ]   KLRC4-KLRK1 [ EBI - ARRAY_EXPRESS ]   KLRC4-KLRK1 [ SEEK ]   KLRC4-KLRK1 [ MEM ]
Gene Expression Viewer (FireBrowse)KLRC4-KLRK1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)100528032
GTEX Portal (Tissue expression)KLRC4-KLRK1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP26718   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP26718  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP26718
Splice isoforms : SwissVarP26718
PhosPhoSitePlusP26718
Domaine pattern : Prosite (Expaxy)C_TYPE_LECTIN_2 (PS50041)   
Domains : Interpro (EBI)C-type_lectin-like    C-type_lectin-like/link    CTDL_fold    NKR-like_CTLD   
Domain families : Pfam (Sanger)Lectin_C (PF00059)   
Domain families : Pfam (NCBI)pfam00059   
Domain families : Smart (EMBL)CLECT (SM00034)  
Conserved Domain (NCBI)KLRC4-KLRK1
DMDM Disease mutations100528032
Blocks (Seattle)KLRC4-KLRK1
PDB (SRS)1HYR    1KCG    1MPU    4PDC    4S0U   
PDB (PDBSum)1HYR    1KCG    1MPU    4PDC    4S0U   
PDB (IMB)1HYR    1KCG    1MPU    4PDC    4S0U   
PDB (RSDB)1HYR    1KCG    1MPU    4PDC    4S0U   
Structural Biology KnowledgeBase1HYR    1KCG    1MPU    4PDC    4S0U   
SCOP (Structural Classification of Proteins)1HYR    1KCG    1MPU    4PDC    4S0U   
CATH (Classification of proteins structures)1HYR    1KCG    1MPU    4PDC    4S0U   
SuperfamilyP26718
Peptide AtlasP26718
IPIIPI00473104   IPI00788649   
Protein Interaction databases
DIP (DOE-UCLA)P26718
IntAct (EBI)P26718
BioGRIDKLRC4-KLRK1
STRING (EMBL)KLRC4-KLRK1
ZODIACKLRC4-KLRK1
Ontologies - Pathways
QuickGOP26718
Ontology : AmiGOstimulatory C-type lectin receptor signaling pathway  adaptive immune response  receptor activity  protein binding  plasma membrane  plasma membrane  integral component of plasma membrane  signal transduction  external side of plasma membrane  cell surface  integral component of membrane  natural killer cell activation  cell differentiation  carbohydrate binding  T cell costimulation  MHC class Ib receptor activity  positive regulation of interferon-gamma production  negative regulation of GTPase activity  MHC class I protein binding  protein homodimerization activity  innate immune response  positive regulation of nitric oxide biosynthetic process  positive regulation of natural killer cell mediated cytotoxicity  regulation of immune response  defense response to Gram-positive bacterium  cellular response to lipopolysaccharide  negative regulation of natural killer cell chemotaxis  
Ontology : EGO-EBIstimulatory C-type lectin receptor signaling pathway  adaptive immune response  receptor activity  protein binding  plasma membrane  plasma membrane  integral component of plasma membrane  signal transduction  external side of plasma membrane  cell surface  integral component of membrane  natural killer cell activation  cell differentiation  carbohydrate binding  T cell costimulation  MHC class Ib receptor activity  positive regulation of interferon-gamma production  negative regulation of GTPase activity  MHC class I protein binding  protein homodimerization activity  innate immune response  positive regulation of nitric oxide biosynthetic process  positive regulation of natural killer cell mediated cytotoxicity  regulation of immune response  defense response to Gram-positive bacterium  cellular response to lipopolysaccharide  negative regulation of natural killer cell chemotaxis  
Pathways : KEGGNatural killer cell mediated cytotoxicity    Malaria   
NDEx NetworkKLRC4-KLRK1
Atlas of Cancer Signalling NetworkKLRC4-KLRK1
Wikipedia pathwaysKLRC4-KLRK1
Orthology - Evolution
OrthoDB100528032
Phylogenetic Trees/Animal Genes : TreeFamKLRC4-KLRK1
HOVERGENP26718
HOGENOMP26718
Homologs : HomoloGeneKLRC4-KLRK1
Homology/Alignments : Family Browser (UCSC)KLRC4-KLRK1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKLRC4-KLRK1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KLRC4-KLRK1
dbVarKLRC4-KLRK1
ClinVarKLRC4-KLRK1
1000_GenomesKLRC4-KLRK1 
Exome Variant ServerKLRC4-KLRK1
ExAC (Exome Aggregation Consortium)KLRC4-KLRK1 (select the gene name)
Genetic variants : HAPMAP100528032
Genomic Variants (DGV)KLRC4-KLRK1 [DGVbeta]
DECIPHERKLRC4-KLRK1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKLRC4-KLRK1 
Mutations
ICGC Data PortalKLRC4-KLRK1 
TCGA Data PortalKLRC4-KLRK1 
Broad Tumor PortalKLRC4-KLRK1
OASIS PortalKLRC4-KLRK1 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDKLRC4-KLRK1
BioMutasearch KLRC4-KLRK1
DgiDB (Drug Gene Interaction Database)KLRC4-KLRK1
DoCM (Curated mutations)KLRC4-KLRK1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KLRC4-KLRK1 (select a term)
intoGenKLRC4-KLRK1
Cancer3DKLRC4-KLRK1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenKLRC4-KLRK1
Genetic Testing Registry KLRC4-KLRK1
NextProtP26718 [Medical]
TSGene100528032
GENETestsKLRC4-KLRK1
Target ValidationKLRC4-KLRK1
Huge Navigator KLRC4-KLRK1 [HugePedia]
snp3D : Map Gene to Disease100528032
BioCentury BCIQKLRC4-KLRK1
ClinGenKLRC4-KLRK1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD100528032
Clinical trialKLRC4-KLRK1
Miscellaneous
canSAR (ICR)KLRC4-KLRK1 (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKLRC4-KLRK1
EVEXKLRC4-KLRK1
GoPubMedKLRC4-KLRK1
iHOPKLRC4-KLRK1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:39:52 CEST 2017

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