KLRC4 (killer cell lectin like receptor C4)

2003-06-01  

Identity

HGNC
LOCATION
12p13.2
LOCUSID
ALIAS
NKG2-F,NKG2F
FUSION GENES

Other Information

Locus ID:

NCBI: 8302
MIM: 602893
HGNC: 6377
Ensembl: ENSG00000183542

Variants:

dbSNP: 8302
ClinVar: 8302
TCGA: ENSG00000183542
COSMIC: KLRC4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000183542ENST00000309384O43908

Expression (GTEx)

0
1
2
3
4
5
6
7
8

Pathways

PathwaySourceExternal ID
Antigen processing and presentationKEGGko04612
Antigen processing and presentationKEGGhsa04612

References

Pubmed IDYearTitleCitations
163972732006Identification of the NKG2D haplotypes associated with natural cytotoxic activity of peripheral blood lymphocytes and cancer immunosurveillance.34
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
260972392015Brief report: association of CCR1, KLRC4, IL12A-AS1, STAT4, and ERAP1 With Behçet's disease in Iranians.10
151405752004Human NKG2F is expressed and can associate with DAP12.9
180066952008Scan of 977 nonsynonymous SNPs in CLL4 trial patients for the identification of genetic variants influencing prognosis.9
206486032010Association of NKG2D genetic polymorphism with susceptibility to chronic hepatitis B in a Han Chinese population.7
208116872010Up-regulation of NKG2F receptor, a functionally unknown killer receptor, of human natural killer cells by interleukin-2 and interleukin-15.2
287062592017Genetic polymorphisms of C-type lectin receptors in Behcet's disease in a Chinese Han population.1

Citation

Dessen P

KLRC4 (killer cell lectin like receptor C4)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/41093/klrc4