Atlas of Genetics and Cytogenetics in Oncology and Haematology

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KLRD1 (killer cell lectin like receptor D1)

Identity

Alias_namesCD94
killer cell lectin-like receptor subfamily D
Other alias
HGNC (Hugo) KLRD1
LocusID (NCBI) 3824
Atlas_Id 52201
Location 12p13.2  [Link to chromosome band 12p13]
Location_base_pair Starts at 10307818 and ends at 10317251 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)KLRD1   6378
Cards
Entrez_Gene (NCBI)KLRD1  3824  killer cell lectin like receptor D1
AliasesCD94
GeneCards (Weizmann)KLRD1
Ensembl hg19 (Hinxton)ENSG00000134539 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000134539 [Gene_View]  ENSG00000134539 [Sequence]  chr12:10307818-10317251 [Contig_View]  KLRD1 [Vega]
ICGC DataPortalENSG00000134539
TCGA cBioPortalKLRD1
AceView (NCBI)KLRD1
Genatlas (Paris)KLRD1
WikiGenes3824
SOURCE (Princeton)KLRD1
Genetics Home Reference (NIH)KLRD1
Genomic and cartography
GoldenPath hg38 (UCSC)KLRD1  -     chr12:10307818-10317251 +  12p13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KLRD1  -     12p13.2   [Description]    (hg19-Feb_2009)
EnsemblKLRD1 - 12p13.2 [CytoView hg19]  KLRD1 - 12p13.2 [CytoView hg38]
Mapping of homologs : NCBIKLRD1 [Mapview hg19]  KLRD1 [Mapview hg38]
OMIM602894   
Gene and transcription
Genbank (Entrez)AB009597 AF498040 AF498041 AJ000001 AK291506
RefSeq transcript (Entrez)NM_001114396 NM_001351060 NM_001351062 NM_001351063 NM_002262 NM_007334
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KLRD1
Cluster EST : UnigeneHs.562457 [ NCBI ]
CGAP (NCI)Hs.562457
Alternative Splicing GalleryENSG00000134539
Gene ExpressionKLRD1 [ NCBI-GEO ]   KLRD1 [ EBI - ARRAY_EXPRESS ]   KLRD1 [ SEEK ]   KLRD1 [ MEM ]
Gene Expression Viewer (FireBrowse)KLRD1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3824
GTEX Portal (Tissue expression)KLRD1
Human Protein AtlasENSG00000134539-KLRD1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13241   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13241  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13241
Splice isoforms : SwissVarQ13241
PhosPhoSitePlusQ13241
Domaine pattern : Prosite (Expaxy)C_TYPE_LECTIN_2 (PS50041)   
Domains : Interpro (EBI)C-type_lectin-like    C-type_lectin-like/link    CTDL_fold    NKR-like_CTLD   
Domain families : Pfam (Sanger)Lectin_C (PF00059)   
Domain families : Pfam (NCBI)pfam00059   
Domain families : Smart (EMBL)CLECT (SM00034)  
Conserved Domain (NCBI)KLRD1
DMDM Disease mutations3824
Blocks (Seattle)KLRD1
PDB (SRS)1B6E    3BDW    3CDG    3CII   
PDB (PDBSum)1B6E    3BDW    3CDG    3CII   
PDB (IMB)1B6E    3BDW    3CDG    3CII   
PDB (RSDB)1B6E    3BDW    3CDG    3CII   
Structural Biology KnowledgeBase1B6E    3BDW    3CDG    3CII   
SCOP (Structural Classification of Proteins)1B6E    3BDW    3CDG    3CII   
CATH (Classification of proteins structures)1B6E    3BDW    3CDG    3CII   
SuperfamilyQ13241
Human Protein Atlas [tissue]ENSG00000134539-KLRD1 [tissue]
Peptide AtlasQ13241
HPRD04204
IPIIPI00012338   IPI00221061   IPI00221062   IPI00981868   IPI00477101   IPI00386247   IPI01011279   
Protein Interaction databases
DIP (DOE-UCLA)Q13241
IntAct (EBI)Q13241
FunCoupENSG00000134539
BioGRIDKLRD1
STRING (EMBL)KLRD1
ZODIACKLRD1
Ontologies - Pathways
QuickGOQ13241
Ontology : AmiGOnatural killer cell mediated immunity  transmembrane signaling receptor activity  protein binding  plasma membrane  cell surface receptor signaling pathway  external side of plasma membrane  integral component of membrane  MHC class I protein complex binding  MHC class Ib protein binding, via antigen binding groove  carbohydrate binding  receptor complex  innate immune response  regulation of immune response  protein antigen binding  
Ontology : EGO-EBInatural killer cell mediated immunity  transmembrane signaling receptor activity  protein binding  plasma membrane  cell surface receptor signaling pathway  external side of plasma membrane  integral component of membrane  MHC class I protein complex binding  MHC class Ib protein binding, via antigen binding groove  carbohydrate binding  receptor complex  innate immune response  regulation of immune response  protein antigen binding  
Pathways : BIOCARTARas-Independent pathway in NK cell-mediated cytotoxicity [Genes]   
Pathways : KEGGNatural killer cell mediated cytotoxicity    Antigen processing and presentation   
NDEx NetworkKLRD1
Atlas of Cancer Signalling NetworkKLRD1
Wikipedia pathwaysKLRD1
Orthology - Evolution
OrthoDB3824
GeneTree (enSembl)ENSG00000134539
Phylogenetic Trees/Animal Genes : TreeFamKLRD1
HOVERGENQ13241
HOGENOMQ13241
Homologs : HomoloGeneKLRD1
Homology/Alignments : Family Browser (UCSC)KLRD1
Gene fusions - Rearrangements
Fusion : QuiverKLRD1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKLRD1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KLRD1
dbVarKLRD1
ClinVarKLRD1
1000_GenomesKLRD1 
Exome Variant ServerKLRD1
ExAC (Exome Aggregation Consortium)ENSG00000134539
GNOMAD BrowserENSG00000134539
Genetic variants : HAPMAP3824
Genomic Variants (DGV)KLRD1 [DGVbeta]
DECIPHERKLRD1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKLRD1 
Mutations
ICGC Data PortalKLRD1 
TCGA Data PortalKLRD1 
Broad Tumor PortalKLRD1
OASIS PortalKLRD1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKLRD1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKLRD1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KLRD1
DgiDB (Drug Gene Interaction Database)KLRD1
DoCM (Curated mutations)KLRD1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KLRD1 (select a term)
intoGenKLRD1
Cancer3DKLRD1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602894   
Orphanet
DisGeNETKLRD1
MedgenKLRD1
Genetic Testing Registry KLRD1
NextProtQ13241 [Medical]
TSGene3824
GENETestsKLRD1
Target ValidationKLRD1
Huge Navigator KLRD1 [HugePedia]
snp3D : Map Gene to Disease3824
BioCentury BCIQKLRD1
ClinGenKLRD1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3824
Chemical/Pharm GKB GenePA30167
Clinical trialKLRD1
Miscellaneous
canSAR (ICR)KLRD1 (select the gene name)
Probes
Litterature
PubMed70 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKLRD1
EVEXKLRD1
GoPubMedKLRD1
iHOPKLRD1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Jun 22 16:32:26 CEST 2018
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