Atlas of Genetics and Cytogenetics in Oncology and Haematology

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KLRD1 (killer cell lectin like receptor D1)

Identity

Alias (NCBI)CD94
HGNC (Hugo) KLRD1
HGNC Previous nameCD94
HGNC Previous namekiller cell lectin-like receptor subfamily D, member 1
LocusID (NCBI) 3824
Atlas_Id 52201
Location 12p13.2  [Link to chromosome band 12p13]
Location_base_pair Starts at 10307818 and ends at 10317251 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

 

Nomenclature
HGNC (Hugo)KLRD1   6378
Cards
Entrez_Gene (NCBI)KLRD1    killer cell lectin like receptor D1
AliasesCD94
GeneCards (Weizmann)KLRD1
Ensembl hg19 (Hinxton)ENSG00000134539 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000134539 [Gene_View]  ENSG00000134539 [Sequence]  chr12:10307818-10317251 [Contig_View]  KLRD1 [Vega]
ICGC DataPortalENSG00000134539
TCGA cBioPortalKLRD1
AceView (NCBI)KLRD1
Genatlas (Paris)KLRD1
SOURCE (Princeton)KLRD1
Genetics Home Reference (NIH)KLRD1
Genomic and cartography
GoldenPath hg38 (UCSC)KLRD1  -     chr12:10307818-10317251 +  12p13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KLRD1  -     12p13.2   [Description]    (hg19-Feb_2009)
GoldenPathKLRD1 - 12p13.2 [CytoView hg19]  KLRD1 - 12p13.2 [CytoView hg38]
ImmunoBaseENSG00000134539
Genome Data Viewer NCBIKLRD1 [Mapview hg19]  
OMIM602894   
Gene and transcription
Genbank (Entrez)AB009597 AF498040 AF498041 AJ000001 AK291506
RefSeq transcript (Entrez)NM_001114396 NM_001351060 NM_001351062 NM_001351063 NM_002262 NM_007334
Consensus coding sequences : CCDS (NCBI)KLRD1
Gene ExpressionKLRD1 [ NCBI-GEO ]   KLRD1 [ EBI - ARRAY_EXPRESS ]   KLRD1 [ SEEK ]   KLRD1 [ MEM ]
Gene Expression Viewer (FireBrowse)KLRD1 [ Firebrowse - Broad ]
GenevisibleExpression of KLRD1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3824
GTEX Portal (Tissue expression)KLRD1
Human Protein AtlasENSG00000134539-KLRD1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13241   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13241  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13241
PhosPhoSitePlusQ13241
Domaine pattern : Prosite (Expaxy)C_TYPE_LECTIN_2 (PS50041)   
Domains : Interpro (EBI)C-type_lectin-like    C-type_lectin-like/link_sf    CTDL_fold    NKR-like_CTLD   
Domain families : Pfam (Sanger)Lectin_C (PF00059)   
Domain families : Pfam (NCBI)pfam00059   
Domain families : Smart (EMBL)CLECT (SM00034)  
Conserved Domain (NCBI)KLRD1
PDB (RSDB)1B6E    3BDW    3CDG    3CII   
PDB Europe1B6E    3BDW    3CDG    3CII   
PDB (PDBSum)1B6E    3BDW    3CDG    3CII   
PDB (IMB)1B6E    3BDW    3CDG    3CII   
Structural Biology KnowledgeBase1B6E    3BDW    3CDG    3CII   
SCOP (Structural Classification of Proteins)1B6E    3BDW    3CDG    3CII   
CATH (Classification of proteins structures)1B6E    3BDW    3CDG    3CII   
SuperfamilyQ13241
AlphaFold pdb e-kbQ13241   
Human Protein Atlas [tissue]ENSG00000134539-KLRD1 [tissue]
HPRD04204
Protein Interaction databases
DIP (DOE-UCLA)Q13241
IntAct (EBI)Q13241
BioGRIDKLRD1
STRING (EMBL)KLRD1
ZODIACKLRD1
Ontologies - Pathways
QuickGOQ13241
Ontology : AmiGOnegative regulation of T cell mediated cytotoxicity  stimulatory C-type lectin receptor signaling pathway  natural killer cell mediated immunity  adaptive immune response  transmembrane signaling receptor activity  protein binding  plasma membrane  integral component of plasma membrane  cell surface receptor signaling pathway  MHC class I protein complex binding  MHC class Ib protein binding, via antigen binding groove  carbohydrate binding  receptor complex  innate immune response  negative regulation of natural killer cell mediated cytotoxicity  positive regulation of natural killer cell mediated cytotoxicity  regulation of immune response  HLA-E specific inhibitory MHC class Ib receptor activity  protein antigen binding  
Ontology : EGO-EBInegative regulation of T cell mediated cytotoxicity  stimulatory C-type lectin receptor signaling pathway  natural killer cell mediated immunity  adaptive immune response  transmembrane signaling receptor activity  protein binding  plasma membrane  integral component of plasma membrane  cell surface receptor signaling pathway  MHC class I protein complex binding  MHC class Ib protein binding, via antigen binding groove  carbohydrate binding  receptor complex  innate immune response  negative regulation of natural killer cell mediated cytotoxicity  positive regulation of natural killer cell mediated cytotoxicity  regulation of immune response  HLA-E specific inhibitory MHC class Ib receptor activity  protein antigen binding  
Pathways : BIOCARTARas-Independent pathway in NK cell-mediated cytotoxicity [Genes]   
Pathways : KEGGAntigen processing and presentation    Natural killer cell mediated cytotoxicity    Graft-versus-host disease   
NDEx NetworkKLRD1
Atlas of Cancer Signalling NetworkKLRD1
Wikipedia pathwaysKLRD1
Orthology - Evolution
OrthoDB3824
GeneTree (enSembl)ENSG00000134539
Phylogenetic Trees/Animal Genes : TreeFamKLRD1
Homologs : HomoloGeneKLRD1
Homology/Alignments : Family Browser (UCSC)KLRD1
Gene fusions - Rearrangements
Fusion : QuiverKLRD1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKLRD1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KLRD1
dbVarKLRD1
ClinVarKLRD1
MonarchKLRD1
1000_GenomesKLRD1 
Exome Variant ServerKLRD1
GNOMAD BrowserENSG00000134539
Varsome BrowserKLRD1
ACMGKLRD1 variants
VarityQ13241
Genomic Variants (DGV)KLRD1 [DGVbeta]
DECIPHERKLRD1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKLRD1 
Mutations
ICGC Data PortalKLRD1 
TCGA Data PortalKLRD1 
Broad Tumor PortalKLRD1
OASIS PortalKLRD1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKLRD1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DKLRD1
Mutations and Diseases : HGMDKLRD1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaKLRD1
DgiDB (Drug Gene Interaction Database)KLRD1
DoCM (Curated mutations)KLRD1
CIViC (Clinical Interpretations of Variants in Cancer)KLRD1
Cancer3DKLRD1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602894   
Orphanet
DisGeNETKLRD1
MedgenKLRD1
Genetic Testing Registry KLRD1
NextProtQ13241 [Medical]
GENETestsKLRD1
Target ValidationKLRD1
Huge Navigator KLRD1 [HugePedia]
ClinGenKLRD1
Clinical trials, drugs, therapy
MyCancerGenomeKLRD1
Protein Interactions : CTDKLRD1
Pharm GKB GenePA30167
PharosQ13241
Clinical trialKLRD1
Miscellaneous
canSAR (ICR)KLRD1
HarmonizomeKLRD1
DataMed IndexKLRD1
Probes
Litterature
PubMed74 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXKLRD1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:15:16 CEST 2021
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