Atlas of Genetics and Cytogenetics in Oncology and Haematology


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KLRG1 (killer cell lectin like receptor G1)

Identity

Alias_namesmember A
Alias_symbol (synonym)MAFA
2F1
MAFA-L
CLEC15A
Other aliasMAFA-2F1
MAFA-LIKE
HGNC (Hugo) KLRG1
LocusID (NCBI) 10219
Atlas_Id 42906
Location 12p13.31  [Link to chromosome band 12p13]
Location_base_pair Starts at 8989625 and ends at 9010744 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KLRG1   6380
Cards
Entrez_Gene (NCBI)KLRG1  10219  killer cell lectin like receptor G1
Aliases2F1; CLEC15A; MAFA; MAFA-2F1; 
MAFA-L; MAFA-LIKE
GeneCards (Weizmann)KLRG1
Ensembl hg19 (Hinxton)ENSG00000139187 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000139187 [Gene_View]  chr12:8989625-9010744 [Contig_View]  KLRG1 [Vega]
ICGC DataPortalENSG00000139187
TCGA cBioPortalKLRG1
AceView (NCBI)KLRG1
Genatlas (Paris)KLRG1
WikiGenes10219
SOURCE (Princeton)KLRG1
Genetics Home Reference (NIH)KLRG1
Genomic and cartography
GoldenPath hg38 (UCSC)KLRG1  -     chr12:8989625-9010744 +  12p13.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KLRG1  -     12p13.31   [Description]    (hg19-Feb_2009)
EnsemblKLRG1 - 12p13.31 [CytoView hg19]  KLRG1 - 12p13.31 [CytoView hg38]
Mapping of homologs : NCBIKLRG1 [Mapview hg19]  KLRG1 [Mapview hg38]
OMIM604874   
Gene and transcription
Genbank (Entrez)AF034952 AF081675 AF097358 AI433079 AK301367
RefSeq transcript (Entrez)NM_001329099 NM_001329101 NM_001329102 NM_001329103 NM_005810
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KLRG1
Cluster EST : UnigeneHs.558446 [ NCBI ]
CGAP (NCI)Hs.558446
Alternative Splicing GalleryENSG00000139187
Gene ExpressionKLRG1 [ NCBI-GEO ]   KLRG1 [ EBI - ARRAY_EXPRESS ]   KLRG1 [ SEEK ]   KLRG1 [ MEM ]
Gene Expression Viewer (FireBrowse)KLRG1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10219
GTEX Portal (Tissue expression)KLRG1
Human Protein AtlasENSG00000139187-KLRG1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96E93   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96E93  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96E93
Splice isoforms : SwissVarQ96E93
PhosPhoSitePlusQ96E93
Domaine pattern : Prosite (Expaxy)C_TYPE_LECTIN_2 (PS50041)   
Domains : Interpro (EBI)C-type_lectin-like    C-type_lectin-like/link    CTDL_fold    NKR-like_CTLD   
Domain families : Pfam (Sanger)Lectin_C (PF00059)   
Domain families : Pfam (NCBI)pfam00059   
Domain families : Smart (EMBL)CLECT (SM00034)  
Conserved Domain (NCBI)KLRG1
DMDM Disease mutations10219
Blocks (Seattle)KLRG1
PDB (SRS)3FF7   
PDB (PDBSum)3FF7   
PDB (IMB)3FF7   
PDB (RSDB)3FF7   
Structural Biology KnowledgeBase3FF7   
SCOP (Structural Classification of Proteins)3FF7   
CATH (Classification of proteins structures)3FF7   
SuperfamilyQ96E93
Human Protein Atlas [tissue]ENSG00000139187-KLRG1 [tissue]
Peptide AtlasQ96E93
HPRD16076
IPIIPI00153018   IPI00478141   IPI01010181   IPI01014981   
Protein Interaction databases
DIP (DOE-UCLA)Q96E93
IntAct (EBI)Q96E93
FunCoupENSG00000139187
BioGRIDKLRG1
STRING (EMBL)KLRG1
ZODIACKLRG1
Ontologies - Pathways
QuickGOQ96E93
Ontology : AmiGOreceptor activity  protein binding  plasma membrane  inflammatory response  cellular defense response  cell surface receptor signaling pathway  integral component of membrane  carbohydrate binding  innate immune response  
Ontology : EGO-EBIreceptor activity  protein binding  plasma membrane  inflammatory response  cellular defense response  cell surface receptor signaling pathway  integral component of membrane  carbohydrate binding  innate immune response  
NDEx NetworkKLRG1
Atlas of Cancer Signalling NetworkKLRG1
Wikipedia pathwaysKLRG1
Orthology - Evolution
OrthoDB10219
GeneTree (enSembl)ENSG00000139187
Phylogenetic Trees/Animal Genes : TreeFamKLRG1
HOVERGENQ96E93
HOGENOMQ96E93
Homologs : HomoloGeneKLRG1
Homology/Alignments : Family Browser (UCSC)KLRG1
Gene fusions - Rearrangements
Fusion: Tumor Portal KLRG1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKLRG1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KLRG1
dbVarKLRG1
ClinVarKLRG1
1000_GenomesKLRG1|/A> 
Exome Variant ServerKLRG1
ExAC (Exome Aggregation Consortium)ENSG00000139187
GNOMAD BrowserENSG00000139187
Genetic variants : HAPMAP10219
Genomic Variants (DGV)KLRG1 [DGVbeta]
DECIPHERKLRG1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKLRG1 
Mutations
ICGC Data PortalKLRG1 
TCGA Data PortalKLRG1 
Broad Tumor PortalKLRG1
OASIS PortalKLRG1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKLRG1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKLRG1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KLRG1
DgiDB (Drug Gene Interaction Database)KLRG1
DoCM (Curated mutations)KLRG1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KLRG1 (select a term)
intoGenKLRG1
Cancer3DKLRG1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604874   
Orphanet
MedgenKLRG1
Genetic Testing Registry KLRG1
NextProtQ96E93 [Medical]
TSGene10219
GENETestsKLRG1
Target ValidationKLRG1
Huge Navigator KLRG1 [HugePedia]
snp3D : Map Gene to Disease10219
BioCentury BCIQKLRG1
ClinGenKLRG1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10219
Chemical/Pharm GKB GenePA30170
Clinical trialKLRG1
Miscellaneous
canSAR (ICR)KLRG1 (select the gene name)
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKLRG1
EVEXKLRG1
GoPubMedKLRG1
iHOPKLRG1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 12:55:44 CET 2017

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