KNDC1 (kinase non-catalytic C-lobe domain containing 1)

2006-10-01  

Identity

HGNC
KNDC1
LOCATION
10q26.3
LOCUSID
85442
ALIAS
C10orf23,RASGEF2,Very-KIND,bB439H18.3,v-KIND
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 85442
MIM: 616237
HGNC: 29374
Ensembl: ENSG00000171798

Variants:

dbSNP: 85442
ClinVar: 85442
TCGA: ENSG00000171798
COSMIC: KNDC1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000171798ENST00000304613Q76NI1
ENSG00000171798ENST00000368571Q76NI1

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
295689292018Effect of KNDC1 overexpression on the senescence of human umbilical vein endothelial cells.3
295689292018Effect of KNDC1 overexpression on the senescence of human umbilical vein endothelial cells.3
247883522014KNDC1 knockdown protects human umbilical vein endothelial cells from senescence.7
247883522014KNDC1 knockdown protects human umbilical vein endothelial cells from senescence.7
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.83
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.83

Citation

Dessen P

KNDC1 (kinase non-catalytic C-lobe domain containing 1)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43334/kndc1