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KNSTRN (kinetochore-localized astrin/SPAG5 binding protein)

Identity

Alias_namesC15orf23
chromosome 15 open reading frame 23
Alias_symbol (synonym)FLJ14502
SKAP
kinastrin
TRAF4AF1
Other aliasHSD11
HGNC (Hugo) KNSTRN
LocusID (NCBI) 90417
Atlas_Id 55018
Location 15q15.1  [Link to chromosome band 15q15]
Location_base_pair Starts at 40674922 and ends at 40686489 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
IVD (15q15.1) / KNSTRN (15q15.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KNSTRN   30767
Cards
Entrez_Gene (NCBI)KNSTRN  90417  kinetochore-localized astrin/SPAG5 binding protein
AliasesC15orf23; HSD11; SKAP; TRAF4AF1
GeneCards (Weizmann)KNSTRN
Ensembl hg19 (Hinxton)ENSG00000128944 [Gene_View]  chr15:40674922-40686489 [Contig_View]  KNSTRN [Vega]
Ensembl hg38 (Hinxton)ENSG00000128944 [Gene_View]  chr15:40674922-40686489 [Contig_View]  KNSTRN [Vega]
ICGC DataPortalENSG00000128944
TCGA cBioPortalKNSTRN
AceView (NCBI)KNSTRN
Genatlas (Paris)KNSTRN
WikiGenes90417
SOURCE (Princeton)KNSTRN
Genetics Home Reference (NIH)KNSTRN
Genomic and cartography
GoldenPath hg19 (UCSC)KNSTRN  -     chr15:40674922-40686489 +  15q15.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)KNSTRN  -     15q15.1   [Description]    (hg38-Dec_2013)
EnsemblKNSTRN - 15q15.1 [CytoView hg19]  KNSTRN - 15q15.1 [CytoView hg38]
Mapping of homologs : NCBIKNSTRN [Mapview hg19]  KNSTRN [Mapview hg38]
OMIM614718   
Gene and transcription
Genbank (Entrez)AK027408 AK125765 AK298156 AK301887 AW156972
RefSeq transcript (Entrez)NM_001142761 NM_001142762 NM_033286
RefSeq genomic (Entrez)NC_000015 NC_018926 NT_010194 NW_004929398
Consensus coding sequences : CCDS (NCBI)KNSTRN
Cluster EST : UnigeneHs.525796 [ NCBI ]
CGAP (NCI)Hs.525796
Alternative Splicing GalleryENSG00000128944
Gene ExpressionKNSTRN [ NCBI-GEO ]   KNSTRN [ EBI - ARRAY_EXPRESS ]   KNSTRN [ SEEK ]   KNSTRN [ MEM ]
Gene Expression Viewer (FireBrowse)KNSTRN [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)90417
GTEX Portal (Tissue expression)KNSTRN
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y448   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y448  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y448
Splice isoforms : SwissVarQ9Y448
PhosPhoSitePlusQ9Y448
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)KNSTRN
DMDM Disease mutations90417
Blocks (Seattle)KNSTRN
SuperfamilyQ9Y448
Human Protein AtlasENSG00000128944
Peptide AtlasQ9Y448
HPRD12669
IPIIPI00294680   IPI00796000   IPI00795574   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y448
IntAct (EBI)Q9Y448
FunCoupENSG00000128944
BioGRIDKNSTRN
STRING (EMBL)KNSTRN
ZODIACKNSTRN
Ontologies - Pathways
QuickGOQ9Y448
Ontology : AmiGOmitotic sister chromatid segregation  kinetochore  condensed chromosome kinetochore  spindle pole  protein binding  nucleus  cytoplasm  spindle organization  chromosome segregation  microtubule cytoskeleton  microtubule plus-end  cell division  regulation of attachment of spindle microtubules to kinetochore  mitotic spindle  
Ontology : EGO-EBImitotic sister chromatid segregation  kinetochore  condensed chromosome kinetochore  spindle pole  protein binding  nucleus  cytoplasm  spindle organization  chromosome segregation  microtubule cytoskeleton  microtubule plus-end  cell division  regulation of attachment of spindle microtubules to kinetochore  mitotic spindle  
NDEx NetworkKNSTRN
Atlas of Cancer Signalling NetworkKNSTRN
Wikipedia pathwaysKNSTRN
Orthology - Evolution
OrthoDB90417
GeneTree (enSembl)ENSG00000128944
Phylogenetic Trees/Animal Genes : TreeFamKNSTRN
HOVERGENQ9Y448
HOGENOMQ9Y448
Homologs : HomoloGeneKNSTRN
Homology/Alignments : Family Browser (UCSC)KNSTRN
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKNSTRN [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KNSTRN
dbVarKNSTRN
ClinVarKNSTRN
1000_GenomesKNSTRN 
Exome Variant ServerKNSTRN
ExAC (Exome Aggregation Consortium)KNSTRN (select the gene name)
Genetic variants : HAPMAP90417
Genomic Variants (DGV)KNSTRN [DGVbeta]
DECIPHER (Syndromes)15:40674922-40686489  ENSG00000128944
CONAN: Copy Number AnalysisKNSTRN 
Mutations
ICGC Data PortalKNSTRN 
TCGA Data PortalKNSTRN 
Broad Tumor PortalKNSTRN
OASIS PortalKNSTRN [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDKNSTRN
BioMutasearch KNSTRN
DgiDB (Drug Gene Interaction Database)KNSTRN
DoCM (Curated mutations)KNSTRN (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KNSTRN (select a term)
intoGenKNSTRN
Cancer3DKNSTRN(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614718   
Orphanet
MedgenKNSTRN
Genetic Testing Registry KNSTRN
NextProtQ9Y448 [Medical]
TSGene90417
GENETestsKNSTRN
Huge Navigator KNSTRN [HugePedia]
snp3D : Map Gene to Disease90417
BioCentury BCIQKNSTRN
ClinGenKNSTRN
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD90417
Chemical/Pharm GKB GenePA134895025
Clinical trialKNSTRN
Miscellaneous
canSAR (ICR)KNSTRN (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKNSTRN
EVEXKNSTRN
GoPubMedKNSTRN
iHOPKNSTRN
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Thu Mar 30 15:06:28 CEST 2017

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