Identity
HGNC
LOCATION
3q25.33
LOCUSID
ALIAS
IPOA3,QIP1,SRP3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3840
MIM: 602970
HGNC: 6397
Ensembl: ENSG00000186432
Variants:
dbSNP: 3840
ClinVar: 3840
TCGA: ENSG00000186432
COSMIC: KPNA4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000186432 | ENST00000334256 | O00629 |
| ENSG00000186432 | ENST00000483437 | H7C4F6 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36573325 | 2023 | Circular RNA hsa_circ_0008003 promotes the progression of non-small-cell lung cancer by sponging miR-548I and regulating KPNA4 expression. | 2 |
| 36573325 | 2023 | Circular RNA hsa_circ_0008003 promotes the progression of non-small-cell lung cancer by sponging miR-548I and regulating KPNA4 expression. | 2 |
| 33188837 | 2021 | KPNA4 regulated by miR-548b-3p promotes the malignant phenotypes of papillary thyroid cancer. | 6 |
| 33535183 | 2021 | Value of KPNA4 as a diagnostic and prognostic biomarker for hepatocellular carcinoma. | 8 |
| 33537823 | 2021 | LINC00467 facilitates osteosarcoma progression by sponging miR‑217 to regulate KPNA4 expression. | 7 |
| 33798680 | 2021 | KPNA4 is involved in cataract formation via the nuclear import of p53. | 4 |
| 33945888 | 2021 | The nuclear localization sequence of the epigenetic factor RYBP binds to human importin α3. | 4 |
| 34930332 | 2021 | Ginsenoside Rg3 inhibits osteosarcoma progression by reducing circ_0003074 expression in a miR-516b-5p/KPNA4-dependent manner. | 4 |
| 33188837 | 2021 | KPNA4 regulated by miR-548b-3p promotes the malignant phenotypes of papillary thyroid cancer. | 6 |
| 33535183 | 2021 | Value of KPNA4 as a diagnostic and prognostic biomarker for hepatocellular carcinoma. | 8 |
| 33537823 | 2021 | LINC00467 facilitates osteosarcoma progression by sponging miR‑217 to regulate KPNA4 expression. | 7 |
| 33798680 | 2021 | KPNA4 is involved in cataract formation via the nuclear import of p53. | 4 |
| 33945888 | 2021 | The nuclear localization sequence of the epigenetic factor RYBP binds to human importin α3. | 4 |
| 34930332 | 2021 | Ginsenoside Rg3 inhibits osteosarcoma progression by reducing circ_0003074 expression in a miR-516b-5p/KPNA4-dependent manner. | 4 |
| 31822798 | 2020 | Disease-specific alteration of karyopherin-α subtype establishes feed-forward oncogenic signaling in head and neck squamous cell carcinoma. | 23 |
Citation
Dessen P
KPNA4 (karyopherin subunit alpha 4)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/41099/kpna4
