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KPNA4 (karyopherin alpha 4 (importin alpha 3))

Identity

Other namesIPOA3
QIP1
SRP3
HGNC (Hugo) KPNA4
LocusID (NCBI) 3840
Location 3q25.33
Location_base_pair Starts at 160212783 and ends at 160283376 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)KPNA4   6397
Cards
Entrez_Gene (NCBI)KPNA4  3840  karyopherin alpha 4 (importin alpha 3)
GeneCards (Weizmann)KPNA4
Ensembl (Hinxton)ENSG00000186432 [Gene_View]  chr3:160212783-160283376 [Contig_View]  KPNA4 [Vega]
ICGC DataPortalENSG00000186432
cBioPortalKPNA4
AceView (NCBI)KPNA4
Genatlas (Paris)KPNA4
WikiGenes3840
SOURCE (Princeton)NM_002268
Genomic and cartography
GoldenPath (UCSC)KPNA4  -  3q25.33   chr3:160212783-160283376 -  3q25.33   [Description]    (hg19-Feb_2009)
EnsemblKPNA4 - 3q25.33 [CytoView]
Mapping of homologs : NCBIKPNA4 [Mapview]
OMIM602970   
Gene and transcription
Genbank (Entrez)AB002533 AF038199 AK021602 AK055675 AK129841
RefSeq transcript (Entrez)NM_002268
RefSeq genomic (Entrez)AC_000135 NC_000003 NC_018914 NT_005612 NW_001838884 NW_004929311
Consensus coding sequences : CCDS (NCBI)KPNA4
Cluster EST : UnigeneHs.467866 [ NCBI ]
CGAP (NCI)Hs.467866
Alternative Splicing : Fast-db (Paris)GSHG0022198
Alternative Splicing GalleryENSG00000186432
Gene ExpressionKPNA4 [ NCBI-GEO ]     KPNA4 [ SEEK ]   KPNA4 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00629 (Uniprot)
NextProtO00629  [Medical]
With graphics : InterProO00629
Splice isoforms : SwissVarO00629 (Swissvar)
Domaine pattern : Prosite (Expaxy)ARM_REPEAT (PS50176)    IBB (PS51214)   
Domains : Interpro (EBI)ARM-like [organisation]   ARM-type_fold [organisation]   Armadillo [organisation]   Importin-a_IBB [organisation]   Importing_su_alpha [organisation]  
Related proteins : CluSTrO00629
Domain families : Pfam (Sanger)Arm (PF00514)    IBB (PF01749)   
Domain families : Pfam (NCBI)pfam00514    pfam01749   
Domain families : Smart (EMBL)ARM (SM00185)  
DMDM Disease mutations3840
Blocks (Seattle)O00629
Human Protein AtlasENSG00000186432 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasO00629
HPRD04275
IPIIPI00012578   IPI00386807   IPI00386960   IPI00946316   
Protein Interaction databases
DIP (DOE-UCLA)O00629
IntAct (EBI)O00629
FunCoupENSG00000186432
BioGRIDKPNA4
InParanoidO00629
Interologous Interaction database O00629
IntegromeDBKPNA4
STRING (EMBL)KPNA4
Ontologies - Pathways
Ontology : AmiGOprotein binding  nucleoplasm  cytosol  NLS-bearing protein import into nucleus  protein transporter activity  cytokine-mediated signaling pathway  extracellular vesicular exosome  
Ontology : EGO-EBIprotein binding  nucleoplasm  cytosol  NLS-bearing protein import into nucleus  protein transporter activity  cytokine-mediated signaling pathway  extracellular vesicular exosome  
Protein Interaction DatabaseKPNA4
Wikipedia pathwaysKPNA4
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)KPNA4
snp3D : Map Gene to Disease3840
SNP (GeneSNP Utah)KPNA4
SNP : HGBaseKPNA4
Genetic variants : HAPMAPKPNA4
Exome VariantKPNA4
1000_GenomesKPNA4 
ICGC programENSG00000186432 
Somatic Mutations in Cancer : COSMICKPNA4 
CONAN: Copy Number AnalysisKPNA4 
Mutations and Diseases : HGMDKPNA4
Mutations and Diseases : intOGenKPNA4
Genomic VariantsKPNA4  KPNA4 [DGVbeta]
dbVarKPNA4
ClinVarKPNA4
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM602970   
MedgenKPNA4
GENETestsKPNA4
Disease Genetic AssociationKPNA4
Huge Navigator KPNA4 [HugePedia]  KPNA4 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneKPNA4
Homology/Alignments : Family Browser (UCSC)KPNA4
Phylogenetic Trees/Animal Genes : TreeFamKPNA4
Chemical/Protein Interactions : CTD3840
Chemical/Pharm GKB GenePA30188
Clinical trialKPNA4
Cancer Resource (Charite)ENSG00000186432
Other databases
Probes
Litterature
PubMed94 Pubmed reference(s) in Entrez
CoreMineKPNA4
iHOPKPNA4
OncoSearchKPNA4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 26 16:52:12 CEST 2014

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