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KPNA7 (karyopherin subunit alpha 7)

Identity

Alias_nameskaryopherin alpha 7 (importin alpha 8)
karyopherin alpha 7
Alias_symbol (synonym)IPOA8
Other alias
HGNC (Hugo) KPNA7
LocusID (NCBI) 402569
Atlas_Id 46946
Location 7q22.1  [Link to chromosome band 7q22]
Location_base_pair Starts at 99173574 and ends at 99207489 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
TMEM130 (7q22.1) / KPNA7 (7q22.1)TMEM130 7q22.1 / KPNA7 7q22.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KPNA7   21839
Cards
Entrez_Gene (NCBI)KPNA7  402569  karyopherin subunit alpha 7
AliasesIPOA8
GeneCards (Weizmann)KPNA7
Ensembl hg19 (Hinxton)ENSG00000185467 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000185467 [Gene_View]  chr7:99173574-99207489 [Contig_View]  KPNA7 [Vega]
ICGC DataPortalENSG00000185467
TCGA cBioPortalKPNA7
AceView (NCBI)KPNA7
Genatlas (Paris)KPNA7
WikiGenes402569
SOURCE (Princeton)KPNA7
Genetics Home Reference (NIH)KPNA7
Genomic and cartography
GoldenPath hg38 (UCSC)KPNA7  -     chr7:99173574-99207489 -  7q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KPNA7  -     7q22.1   [Description]    (hg19-Feb_2009)
EnsemblKPNA7 - 7q22.1 [CytoView hg19]  KPNA7 - 7q22.1 [CytoView hg38]
Mapping of homologs : NCBIKPNA7 [Mapview hg19]  KPNA7 [Mapview hg38]
OMIM614107   
Gene and transcription
Genbank (Entrez)AW193472 EU126604
RefSeq transcript (Entrez)NM_001145715
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KPNA7
Cluster EST : UnigeneHs.253050 [ NCBI ]
CGAP (NCI)Hs.253050
Alternative Splicing GalleryENSG00000185467
Gene ExpressionKPNA7 [ NCBI-GEO ]   KPNA7 [ EBI - ARRAY_EXPRESS ]   KPNA7 [ SEEK ]   KPNA7 [ MEM ]
Gene Expression Viewer (FireBrowse)KPNA7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)402569
GTEX Portal (Tissue expression)KPNA7
Human Protein AtlasENSG00000185467-KPNA7 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtA9QM74   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA9QM74  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA9QM74
Splice isoforms : SwissVarA9QM74
PhosPhoSitePlusA9QM74
Domaine pattern : Prosite (Expaxy)ARM_REPEAT (PS50176)    IBB (PS51214)   
Domains : Interpro (EBI)ARM-like    ARM-type_fold    Arm_3    Armadillo    Importin-a_IBB    Importing_su_alpha   
Domain families : Pfam (Sanger)Arm (PF00514)    Arm_3 (PF16186)    IBB (PF01749)   
Domain families : Pfam (NCBI)pfam00514    pfam16186    pfam01749   
Domain families : Smart (EMBL)ARM (SM00185)  
Conserved Domain (NCBI)KPNA7
DMDM Disease mutations402569
Blocks (Seattle)KPNA7
SuperfamilyA9QM74
Human Protein Atlas [tissue]ENSG00000185467-KPNA7 [tissue]
Peptide AtlasA9QM74
IPIIPI00374362   
Protein Interaction databases
DIP (DOE-UCLA)A9QM74
IntAct (EBI)A9QM74
FunCoupENSG00000185467
BioGRIDKPNA7
STRING (EMBL)KPNA7
ZODIACKPNA7
Ontologies - Pathways
QuickGOA9QM74
Ontology : AmiGOnuclear pore  nucleoplasm  nucleoplasm  cytosol  cytosol  NLS-bearing protein import into nucleus  nuclear localization sequence binding  protein transporter activity  modulation by virus of host process  intracellular transport of virus  
Ontology : EGO-EBInuclear pore  nucleoplasm  nucleoplasm  cytosol  cytosol  NLS-bearing protein import into nucleus  nuclear localization sequence binding  protein transporter activity  modulation by virus of host process  intracellular transport of virus  
NDEx NetworkKPNA7
Atlas of Cancer Signalling NetworkKPNA7
Wikipedia pathwaysKPNA7
Orthology - Evolution
OrthoDB402569
GeneTree (enSembl)ENSG00000185467
Phylogenetic Trees/Animal Genes : TreeFamKPNA7
HOVERGENA9QM74
HOGENOMA9QM74
Homologs : HomoloGeneKPNA7
Homology/Alignments : Family Browser (UCSC)KPNA7
Gene fusions - Rearrangements
Fusion : MitelmanTMEM130/KPNA7 [7q22.1/7q22.1]  [t(7;7)(q22;q22)]  
Fusion: TCGATMEM130 7q22.1 KPNA7 7q22.1 BRCA
Fusion: Tumor Portal KPNA7
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKPNA7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KPNA7
dbVarKPNA7
ClinVarKPNA7
1000_GenomesKPNA7 
Exome Variant ServerKPNA7
ExAC (Exome Aggregation Consortium)ENSG00000185467
GNOMAD BrowserENSG00000185467
Genetic variants : HAPMAP402569
Genomic Variants (DGV)KPNA7 [DGVbeta]
DECIPHERKPNA7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKPNA7 
Mutations
ICGC Data PortalKPNA7 
TCGA Data PortalKPNA7 
Broad Tumor PortalKPNA7
OASIS PortalKPNA7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKPNA7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKPNA7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KPNA7
DgiDB (Drug Gene Interaction Database)KPNA7
DoCM (Curated mutations)KPNA7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KPNA7 (select a term)
intoGenKPNA7
Cancer3DKPNA7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614107   
Orphanet22859   
MedgenKPNA7
Genetic Testing Registry KPNA7
NextProtA9QM74 [Medical]
TSGene402569
GENETestsKPNA7
Target ValidationKPNA7
Huge Navigator KPNA7 [HugePedia]
snp3D : Map Gene to Disease402569
BioCentury BCIQKPNA7
ClinGenKPNA7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD402569
Chemical/Pharm GKB GenePA164722048
Clinical trialKPNA7
Miscellaneous
canSAR (ICR)KPNA7 (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKPNA7
EVEXKPNA7
GoPubMedKPNA7
iHOPKPNA7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 12:55:48 CET 2017

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