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KREMEN1 (kringle containing transmembrane protein 1)

Identity

Alias_namesKREMEN
kringle containing transmembrane protein
Alias_symbol (synonym)KRM1
Other aliasECTD13
HGNC (Hugo) KREMEN1
LocusID (NCBI) 83999
Atlas_Id 55727
Location 22q12.1  [Link to chromosome band 22q12]
Location_base_pair Starts at 29073078 and ends at 29146820 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
KREMEN1 (22q12.1) / ENTHD1 (22q13.1)KREMEN1 (22q12.1) / OLFM2 (19p13.2)SERPINA1 (14q32.13) / KREMEN1 (22q12.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KREMEN1   17550
Cards
Entrez_Gene (NCBI)KREMEN1  83999  kringle containing transmembrane protein 1
AliasesECTD13; KREMEN; KRM1
GeneCards (Weizmann)KREMEN1
Ensembl hg19 (Hinxton)ENSG00000183762 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000183762 [Gene_View]  chr22:29073078-29146820 [Contig_View]  KREMEN1 [Vega]
ICGC DataPortalENSG00000183762
TCGA cBioPortalKREMEN1
AceView (NCBI)KREMEN1
Genatlas (Paris)KREMEN1
WikiGenes83999
SOURCE (Princeton)KREMEN1
Genetics Home Reference (NIH)KREMEN1
Genomic and cartography
GoldenPath hg38 (UCSC)KREMEN1  -     chr22:29073078-29146820 +  22q12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KREMEN1  -     22q12.1   [Description]    (hg19-Feb_2009)
EnsemblKREMEN1 - 22q12.1 [CytoView hg19]  KREMEN1 - 22q12.1 [CytoView hg38]
Mapping of homologs : NCBIKREMEN1 [Mapview hg19]  KREMEN1 [Mapview hg38]
OMIM609898   617392   
Gene and transcription
Genbank (Entrez)AB059618 AI085656 AK056425 AK172861 AL533967
RefSeq transcript (Entrez)NM_001039570 NM_032045 NM_153379
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KREMEN1
Cluster EST : UnigeneHs.229335 [ NCBI ]
CGAP (NCI)Hs.229335
Alternative Splicing GalleryENSG00000183762
Gene ExpressionKREMEN1 [ NCBI-GEO ]   KREMEN1 [ EBI - ARRAY_EXPRESS ]   KREMEN1 [ SEEK ]   KREMEN1 [ MEM ]
Gene Expression Viewer (FireBrowse)KREMEN1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)83999
GTEX Portal (Tissue expression)KREMEN1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96MU8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96MU8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96MU8
Splice isoforms : SwissVarQ96MU8
PhosPhoSitePlusQ96MU8
Domaine pattern : Prosite (Expaxy)CUB (PS01180)    KRINGLE_1 (PS00021)    KRINGLE_2 (PS50070)    WSC (PS51212)   
Domains : Interpro (EBI)CUB_dom    Kremen    Kringle    Kringle-like    Kringle_CS    WSC_carb-bd   
Domain families : Pfam (Sanger)CUB (PF00431)    Kringle (PF00051)    WSC (PF01822)   
Domain families : Pfam (NCBI)pfam00431    pfam00051    pfam01822   
Domain families : Smart (EMBL)CUB (SM00042)  KR (SM00130)  WSC (SM00321)  
Conserved Domain (NCBI)KREMEN1
DMDM Disease mutations83999
Blocks (Seattle)KREMEN1
PDB (SRS)5FWS    5FWT    5FWU    5FWV    5FWW   
PDB (PDBSum)5FWS    5FWT    5FWU    5FWV    5FWW   
PDB (IMB)5FWS    5FWT    5FWU    5FWV    5FWW   
PDB (RSDB)5FWS    5FWT    5FWU    5FWV    5FWW   
Structural Biology KnowledgeBase5FWS    5FWT    5FWU    5FWV    5FWW   
SCOP (Structural Classification of Proteins)5FWS    5FWT    5FWU    5FWV    5FWW   
CATH (Classification of proteins structures)5FWS    5FWT    5FWU    5FWV    5FWW   
SuperfamilyQ96MU8
Human Protein AtlasENSG00000183762
Peptide AtlasQ96MU8
HPRD11182
IPIIPI00140177   IPI00218929   IPI00651704   IPI00878720   
Protein Interaction databases
DIP (DOE-UCLA)Q96MU8
IntAct (EBI)Q96MU8
FunCoupENSG00000183762
BioGRIDKREMEN1
STRING (EMBL)KREMEN1
ZODIACKREMEN1
Ontologies - Pathways
QuickGOQ96MU8
Ontology : AmiGOprotein binding  apoptotic process  cell communication  membrane  integral component of membrane  Wnt signaling pathway  negative regulation of ossification  limb development  regulation of canonical Wnt signaling pathway  negative regulation of canonical Wnt signaling pathway  
Ontology : EGO-EBIprotein binding  apoptotic process  cell communication  membrane  integral component of membrane  Wnt signaling pathway  negative regulation of ossification  limb development  regulation of canonical Wnt signaling pathway  negative regulation of canonical Wnt signaling pathway  
NDEx NetworkKREMEN1
Atlas of Cancer Signalling NetworkKREMEN1
Wikipedia pathwaysKREMEN1
Orthology - Evolution
OrthoDB83999
GeneTree (enSembl)ENSG00000183762
Phylogenetic Trees/Animal Genes : TreeFamKREMEN1
HOVERGENQ96MU8
HOGENOMQ96MU8
Homologs : HomoloGeneKREMEN1
Homology/Alignments : Family Browser (UCSC)KREMEN1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKREMEN1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KREMEN1
dbVarKREMEN1
ClinVarKREMEN1
1000_GenomesKREMEN1 
Exome Variant ServerKREMEN1
ExAC (Exome Aggregation Consortium)KREMEN1 (select the gene name)
Genetic variants : HAPMAP83999
Genomic Variants (DGV)KREMEN1 [DGVbeta]
DECIPHERKREMEN1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKREMEN1 
Mutations
ICGC Data PortalKREMEN1 
TCGA Data PortalKREMEN1 
Broad Tumor PortalKREMEN1
OASIS PortalKREMEN1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKREMEN1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKREMEN1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KREMEN1
DgiDB (Drug Gene Interaction Database)KREMEN1
DoCM (Curated mutations)KREMEN1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KREMEN1 (select a term)
intoGenKREMEN1
Cancer3DKREMEN1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609898    617392   
Orphanet
MedgenKREMEN1
Genetic Testing Registry KREMEN1
NextProtQ96MU8 [Medical]
TSGene83999
GENETestsKREMEN1
Target ValidationKREMEN1
Huge Navigator KREMEN1 [HugePedia]
snp3D : Map Gene to Disease83999
BioCentury BCIQKREMEN1
ClinGenKREMEN1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD83999
Chemical/Pharm GKB GenePA38241
Clinical trialKREMEN1
Miscellaneous
canSAR (ICR)KREMEN1 (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKREMEN1
EVEXKREMEN1
GoPubMedKREMEN1
iHOPKREMEN1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:39:57 CEST 2017

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