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Taking over the Atlas
Dear Colleagues,
The Atlas, once more, is in great danger, and I will have to proceed to a collective economic lay-off of all the team involved in the Atlas before the begining of April 2015 (a foundation having suddenly withdrawn its commitment to support the Atlas). I ask you herein if any Scientific Society (a Society of Cytogenetics, of Clinical Genetics, of Hematology, or a Cancer Society, or any other...), any University and/or Hospital, any Charity, or any database would be interested in taking over the Atlas, in whole or in part. If taking charge of the whole lot is too big, a consortium of various actors could be the solution (I am myself trying to find partners). Could you please spread the information, contact the relevant authorities, and find partners.
Survival of the Atlas will be critically dependant upon your ability to find solutions (and urgently!).
Kind regards.
Jean-Loup Huret
Donations are also welcome

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KRT1 (keratin 1)

Identity

Other namesCK1
EHK
EHK1
EPPK
K1
KRT1A
NEPPK
HGNC (Hugo) KRT1
LocusID (NCBI) 3848
Location 12q13.13
Location_base_pair Starts at 53068520 and ends at 53074191 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

External links

Nomenclature
HGNC (Hugo)KRT1   6412
Cards
Entrez_Gene (NCBI)KRT1  3848  keratin 1
GeneCards (Weizmann)KRT1
Ensembl hg19 (Hinxton)ENSG00000167768 [Gene_View]  chr12:53068520-53074191 [Contig_View]  KRT1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000167768 [Gene_View]  chr12:53068520-53074191 [Contig_View]  KRT1 [Vega]
ICGC DataPortalENSG00000167768
cBioPortalKRT1
AceView (NCBI)KRT1
Genatlas (Paris)KRT1
WikiGenes3848
SOURCE (Princeton)KRT1
Genomic and cartography
GoldenPath hg19 (UCSC)KRT1  -     chr12:53068520-53074191 -  12q13.13   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)KRT1  -     12q13.13   [Description]    (hg38-Dec_2013)
EnsemblKRT1 - 12q13.13 [CytoView hg19]  KRT1 - 12q13.13 [CytoView hg38]
Mapping of homologs : NCBIKRT1 [Mapview hg19]  KRT1 [Mapview hg38]
OMIM113800   139350   144200   146590   600962   607602   607654   
Gene and transcription
Genbank (Entrez)AK313986 BC063697 DB112126 M10938
RefSeq transcript (Entrez)NM_006121
RefSeq genomic (Entrez)AC_000144 NC_000012 NC_018923 NG_008364 NT_029419 NW_001838059 NW_004929384
Consensus coding sequences : CCDS (NCBI)KRT1
Cluster EST : UnigeneHs.80828 [ NCBI ]
CGAP (NCI)Hs.80828
Alternative Splicing : Fast-db (Paris)GSHG0007492
Alternative Splicing GalleryENSG00000167768
Gene ExpressionKRT1 [ NCBI-GEO ]     KRT1 [ SEEK ]   KRT1 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP04264 (Uniprot)
NextProtP04264  [Medical]
With graphics : InterProP04264
Splice isoforms : SwissVarP04264 (Swissvar)
Domaine pattern : Prosite (Expaxy)IF (PS00226)   
Domains : Interpro (EBI)IF    Intermediate_filament_CS    Keratin_II   
Related proteins : CluSTrP04264
Domain families : Pfam (Sanger)Filament (PF00038)   
Domain families : Pfam (NCBI)pfam00038   
DMDM Disease mutations3848
Blocks (Seattle)P04264
Human Protein AtlasENSG00000167768
Peptide AtlasP04264
HPRD00763
IPIIPI00220327   
Protein Interaction databases
DIP (DOE-UCLA)P04264
IntAct (EBI)P04264
FunCoupENSG00000167768
BioGRIDKRT1
IntegromeDBKRT1
STRING (EMBL)KRT1
Ontologies - Pathways
QuickGOP04264
Ontology : AmiGOcomplement activation, lectin pathway  retina homeostasis  receptor activity  structural molecule activity  protein binding  extracellular space  nucleus  cytoskeleton  plasma membrane  response to oxidative stress  membrane  carbohydrate binding  fibrinolysis  keratin filament  regulation of angiogenesis  extracellular vesicular exosome  blood microparticle  
Ontology : EGO-EBIcomplement activation, lectin pathway  retina homeostasis  receptor activity  structural molecule activity  protein binding  extracellular space  nucleus  cytoskeleton  plasma membrane  response to oxidative stress  membrane  carbohydrate binding  fibrinolysis  keratin filament  regulation of angiogenesis  extracellular vesicular exosome  blood microparticle  
Protein Interaction DatabaseKRT1
DoCM (Curated mutations)KRT1
Wikipedia pathwaysKRT1
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerKRT1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KRT1
dbVarKRT1
ClinVarKRT1
1000_GenomesKRT1 
Exome Variant ServerKRT1
SNP (GeneSNP Utah)KRT1
SNP : HGBaseKRT1
Genetic variants : HAPMAPKRT1
Genomic Variants (DGV)KRT1 [DGVbeta]
Mutations
ICGC Data PortalENSG00000167768 
Somatic Mutations in Cancer : COSMICKRT1 
CONAN: Copy Number AnalysisKRT1 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Mendelian genes
LOVD (Leiden Open Variation Database)Zhejiang University Center for Genetic and Genomic Medicine (ZJU-CGGM)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)12:53068520-53074191
Mutations and Diseases : HGMDKRT1
OMIM113800    139350    144200    146590    600962    607602    607654   
MedgenKRT1
NextProtP04264 [Medical]
GENETestsKRT1
Disease Genetic AssociationKRT1
Huge Navigator KRT1 [HugePedia]  KRT1 [HugeCancerGEM]
snp3D : Map Gene to Disease3848
DGIdb (Drug Gene Interaction db)KRT1
General knowledge
Homologs : HomoloGeneKRT1
Homology/Alignments : Family Browser (UCSC)KRT1
Phylogenetic Trees/Animal Genes : TreeFamKRT1
Chemical/Protein Interactions : CTD3848
Chemical/Pharm GKB GenePA30199
Clinical trialKRT1
Cancer Resource (Charite)ENSG00000167768
Other databases
Probes
Litterature
PubMed103 Pubmed reference(s) in Entrez
CoreMineKRT1
GoPubMedKRT1
iHOPKRT1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Feb 14 16:29:58 CET 2015

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