Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

KRT12 (keratin 12, type I)

Identity

Alias_nameskeratin 12, type I
Alias_symbol (synonym)K12
Other alias
HGNC (Hugo) KRT12
LocusID (NCBI) 3859
Atlas_Id 65008
Location 17q21.2  [Link to chromosome band 17q21]
Location_base_pair Starts at 39017430 and ends at 39023462 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
KRT12 (17q21.2) / LSP1 (11p15.5)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KRT12   6414
Cards
Entrez_Gene (NCBI)KRT12  3859  keratin 12, type I
AliasesK12
GeneCards (Weizmann)KRT12
Ensembl hg19 (Hinxton)ENSG00000187242 [Gene_View]  chr17:39017430-39023462 [Contig_View]  KRT12 [Vega]
Ensembl hg38 (Hinxton)ENSG00000187242 [Gene_View]  chr17:39017430-39023462 [Contig_View]  KRT12 [Vega]
ICGC DataPortalENSG00000187242
TCGA cBioPortalKRT12
AceView (NCBI)KRT12
Genatlas (Paris)KRT12
WikiGenes3859
SOURCE (Princeton)KRT12
Genetics Home Reference (NIH)KRT12
Genomic and cartography
GoldenPath hg19 (UCSC)KRT12  -     chr17:39017430-39023462 -  17q21.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)KRT12  -     17q21.2   [Description]    (hg38-Dec_2013)
EnsemblKRT12 - 17q21.2 [CytoView hg19]  KRT12 - 17q21.2 [CytoView hg38]
Mapping of homologs : NCBIKRT12 [Mapview hg19]  KRT12 [Mapview hg38]
OMIM122100   601687   
Gene and transcription
Genbank (Entrez)AK313747 BC156641 CV573989 D78367
RefSeq transcript (Entrez)NM_000223
RefSeq genomic (Entrez)NC_000017 NC_018928 NG_008077 NT_010783 NW_003871091 NW_004929407
Consensus coding sequences : CCDS (NCBI)KRT12
Cluster EST : UnigeneHs.66739 [ NCBI ]
CGAP (NCI)Hs.66739
Alternative Splicing GalleryENSG00000187242
Gene ExpressionKRT12 [ NCBI-GEO ]   KRT12 [ EBI - ARRAY_EXPRESS ]   KRT12 [ SEEK ]   KRT12 [ MEM ]
Gene Expression Viewer (FireBrowse)KRT12 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3859
GTEX Portal (Tissue expression)KRT12
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99456   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ99456  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ99456
Splice isoforms : SwissVarQ99456
PhosPhoSitePlusQ99456
Domaine pattern : Prosite (Expaxy)IF (PS00226)   
Domains : Interpro (EBI)IF    Intermediate_filament_CS    Keratin_I   
Domain families : Pfam (Sanger)Filament (PF00038)   
Domain families : Pfam (NCBI)pfam00038   
Conserved Domain (NCBI)KRT12
DMDM Disease mutations3859
Blocks (Seattle)KRT12
SuperfamilyQ99456
Human Protein AtlasENSG00000187242
Peptide AtlasQ99456
HPRD03405
IPIIPI00015309   
Protein Interaction databases
DIP (DOE-UCLA)Q99456
IntAct (EBI)Q99456
FunCoupENSG00000187242
BioGRIDKRT12
STRING (EMBL)KRT12
ZODIACKRT12
Ontologies - Pathways
QuickGOQ99456
Ontology : AmiGOstructural molecule activity  intermediate filament  visual perception  epithelium development  cornea development in camera-type eye  extracellular exosome  
Ontology : EGO-EBIstructural molecule activity  intermediate filament  visual perception  epithelium development  cornea development in camera-type eye  extracellular exosome  
NDEx NetworkKRT12
Atlas of Cancer Signalling NetworkKRT12
Wikipedia pathwaysKRT12
Orthology - Evolution
OrthoDB3859
GeneTree (enSembl)ENSG00000187242
Phylogenetic Trees/Animal Genes : TreeFamKRT12
HOVERGENQ99456
HOGENOMQ99456
Homologs : HomoloGeneKRT12
Homology/Alignments : Family Browser (UCSC)KRT12
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKRT12 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KRT12
dbVarKRT12
ClinVarKRT12
1000_GenomesKRT12 
Exome Variant ServerKRT12
ExAC (Exome Aggregation Consortium)KRT12 (select the gene name)
Genetic variants : HAPMAP3859
Genomic Variants (DGV)KRT12 [DGVbeta]
DECIPHER (Syndromes)17:39017430-39023462  ENSG00000187242
CONAN: Copy Number AnalysisKRT12 
Mutations
ICGC Data PortalKRT12 
TCGA Data PortalKRT12 
Broad Tumor PortalKRT12
OASIS PortalKRT12 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKRT12  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKRT12
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KRT12
DgiDB (Drug Gene Interaction Database)KRT12
DoCM (Curated mutations)KRT12 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KRT12 (select a term)
intoGenKRT12
Cancer3DKRT12(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM122100    601687   
Orphanet13971   
MedgenKRT12
Genetic Testing Registry KRT12
NextProtQ99456 [Medical]
TSGene3859
GENETestsKRT12
Huge Navigator KRT12 [HugePedia]
snp3D : Map Gene to Disease3859
BioCentury BCIQKRT12
ClinGenKRT12
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3859
Chemical/Pharm GKB GenePA30201
Clinical trialKRT12
Miscellaneous
canSAR (ICR)KRT12 (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKRT12
EVEXKRT12
GoPubMedKRT12
iHOPKRT12
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 12:10:09 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.