Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

KRT14 (keratin 14)

Identity

Other namesCK14
EBS3
EBS4
K14
NFJ
HGNC (Hugo) KRT14
LocusID (NCBI) 3861
Atlas_Id 50134
Location 17q21.2
Location_base_pair Starts at 39738531 and ends at 39743147 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
KRT14 (17q21.2) / ARFGEF2 (20q13.13)KRT14 (17q21.2) / CYP2C18 (10q23.33)KRT14 17q21.2 / ARFGEF2 20q13.13
KRT14 17q21.2 / CYP2C18 10q23.33

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KRT14   6416
Cards
Entrez_Gene (NCBI)KRT14  3861  keratin 14
GeneCards (Weizmann)KRT14
Ensembl hg19 (Hinxton)ENSG00000186847 [Gene_View]  chr17:39738531-39743147 [Contig_View]  KRT14 [Vega]
Ensembl hg38 (Hinxton)ENSG00000186847 [Gene_View]  chr17:39738531-39743147 [Contig_View]  KRT14 [Vega]
ICGC DataPortalENSG00000186847
TCGA cBioPortalKRT14
AceView (NCBI)KRT14
Genatlas (Paris)KRT14
WikiGenes3861
SOURCE (Princeton)KRT14
Genomic and cartography
GoldenPath hg19 (UCSC)KRT14  -     chr17:39738531-39743147 -  17q21.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)KRT14  -     17q21.2   [Description]    (hg38-Dec_2013)
EnsemblKRT14 - 17q21.2 [CytoView hg19]  KRT14 - 17q21.2 [CytoView hg38]
Mapping of homologs : NCBIKRT14 [Mapview hg19]  KRT14 [Mapview hg38]
OMIM125595   131760   131800   131900   148066   161000   601001   
Gene and transcription
Genbank (Entrez)AK309280 BC002690 BC019097 BC042437 BC094830
RefSeq transcript (Entrez)NM_000526
RefSeq genomic (Entrez)NC_000017 NC_018928 NG_008624 NT_010783 NW_004929407
Consensus coding sequences : CCDS (NCBI)KRT14
Cluster EST : UnigeneHs.654380 [ NCBI ]
CGAP (NCI)Hs.654380
Alternative Splicing GalleryENSG00000186847
Gene ExpressionKRT14 [ NCBI-GEO ]   KRT14 [ EBI - ARRAY_EXPRESS ]   KRT14 [ SEEK ]   KRT14 [ MEM ]
Gene Expression Viewer (FireBrowse)KRT14 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3861
GTEX Portal (Tissue expression)KRT14
Protein : pattern, domain, 3D structure
UniProt/SwissProtP02533 (Uniprot)
NextProtP02533  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP02533
Splice isoforms : SwissVarP02533 (Swissvar)
PhosPhoSitePlusP02533
Domaine pattern : Prosite (Expaxy)IF (PS00226)   
Domains : Interpro (EBI)IF    Intermediate_filament_CS    Keratin_I    Prefoldin   
Domain families : Pfam (Sanger)Filament (PF00038)   
Domain families : Pfam (NCBI)pfam00038   
DMDM Disease mutations3861
Blocks (Seattle)KRT14
PDB (SRS)3TNU   
PDB (PDBSum)3TNU   
PDB (IMB)3TNU   
PDB (RSDB)3TNU   
Structural Biology KnowledgeBase3TNU   
SCOP (Structural Classification of Proteins)3TNU   
CATH (Classification of proteins structures)3TNU   
SuperfamilyP02533
Human Protein AtlasENSG00000186847
Peptide AtlasP02533
HPRD01017
IPIIPI00384444   IPI00654614   
Protein Interaction databases
DIP (DOE-UCLA)P02533
IntAct (EBI)P02533
FunCoupENSG00000186847
BioGRIDKRT14
STRING (EMBL)KRT14
ZODIACKRT14
Ontologies - Pathways
QuickGOP02533
Ontology : AmiGOstructural constituent of cytoskeleton  protein binding  nucleus  cytoplasm  cytosol  intermediate filament  aging  epidermis development  response to zinc ion  response to ionizing radiation  epithelial cell differentiation  hemidesmosome assembly  hair cycle  keratin filament  intermediate filament bundle assembly  extracellular exosome  cell periphery  keratin filament binding  
Ontology : EGO-EBIstructural constituent of cytoskeleton  protein binding  nucleus  cytoplasm  cytosol  intermediate filament  aging  epidermis development  response to zinc ion  response to ionizing radiation  epithelial cell differentiation  hemidesmosome assembly  hair cycle  keratin filament  intermediate filament bundle assembly  extracellular exosome  cell periphery  keratin filament binding  
NDEx Network
Atlas of Cancer Signalling NetworkKRT14
Wikipedia pathwaysKRT14
Orthology - Evolution
OrthoDB3861
GeneTree (enSembl)ENSG00000186847
Phylogenetic Trees/Animal Genes : TreeFamKRT14
Homologs : HomoloGeneKRT14
Homology/Alignments : Family Browser (UCSC)KRT14
Gene fusions - Rearrangements
Fusion: TCGAKRT14 17q21.2 ARFGEF2 20q13.13 HNSC
Fusion: TCGAKRT14 17q21.2 CYP2C18 10q23.33 HNSC
Polymorphisms : SNP, variants
NCBI Variation ViewerKRT14 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KRT14
dbVarKRT14
ClinVarKRT14
1000_GenomesKRT14 
Exome Variant ServerKRT14
ExAC (Exome Aggregation Consortium)KRT14 (select the gene name)
Genetic variants : HAPMAP3861
Genomic Variants (DGV)KRT14 [DGVbeta]
Mutations
ICGC Data PortalKRT14 
TCGA Data PortalKRT14 
Broad Tumor PortalKRT14
OASIS PortalKRT14 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKRT14 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Zhejiang University Center for Genetic and Genomic Medicine (ZJU-CGGM)
BioMutasearch KRT14
DgiDB (Drug Gene Interaction Database)KRT14
DoCM (Curated mutations)KRT14 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KRT14 (select a term)
intoGenKRT14
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)17:39738531-39743147  ENSG00000186847
CONAN: Copy Number AnalysisKRT14 
Mutations and Diseases : HGMDKRT14
OMIM125595    131760    131800    131900    148066    161000    601001   
MedgenKRT14
Genetic Testing Registry KRT14
NextProtP02533 [Medical]
TSGene3861
GENETestsKRT14
Huge Navigator KRT14 [HugePedia]
snp3D : Map Gene to Disease3861
BioCentury BCIQKRT14
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3861
Chemical/Pharm GKB GenePA30203
Clinical trialKRT14
Miscellaneous
canSAR (ICR)KRT14 (select the gene name)
Probes
Litterature
PubMed123 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKRT14
EVEXKRT14
GoPubMedKRT14
iHOPKRT14
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sun May 8 18:52:14 CEST 2016

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.