Atlas of Genetics and Cytogenetics in Oncology and Haematology

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KRT15 (keratin 15)

Identity

Alias_nameskeratin 15
Alias_symbol (synonym)K15
CK15
K1CO
Other alias
HGNC (Hugo) KRT15
LocusID (NCBI) 3866
Atlas_Id 50481
Location 17q21.2  [Link to chromosome band 17q21]
Location_base_pair Starts at 41513745 and ends at 41519018 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ZDHHC9 (Xq26.1) / KRT15 (17q21.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)KRT15   6421
Cards
Entrez_Gene (NCBI)KRT15  3866  keratin 15
AliasesCK15; K15; K1CO
GeneCards (Weizmann)KRT15
Ensembl hg19 (Hinxton)ENSG00000171346 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000171346 [Gene_View]  ENSG00000171346 [Sequence]  chr17:41513745-41519018 [Contig_View]  KRT15 [Vega]
ICGC DataPortalENSG00000171346
TCGA cBioPortalKRT15
AceView (NCBI)KRT15
Genatlas (Paris)KRT15
WikiGenes3866
SOURCE (Princeton)KRT15
Genetics Home Reference (NIH)KRT15
Genomic and cartography
GoldenPath hg38 (UCSC)KRT15  -     chr17:41513745-41519018 -  17q21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KRT15  -     17q21.2   [Description]    (hg19-Feb_2009)
GoldenPathKRT15 - 17q21.2 [CytoView hg19]  KRT15 - 17q21.2 [CytoView hg38]
ImmunoBaseENSG00000171346
Mapping of homologs : NCBIKRT15 [Mapview hg19]  KRT15 [Mapview hg38]
OMIM148030   
Gene and transcription
Genbank (Entrez)AK090604 AK091239 AK122864 AK304059 AL832226
RefSeq transcript (Entrez)NM_002275
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KRT15
Cluster EST : UnigeneHs.654570 [ NCBI ]
CGAP (NCI)Hs.654570
Alternative Splicing GalleryENSG00000171346
Gene ExpressionKRT15 [ NCBI-GEO ]   KRT15 [ EBI - ARRAY_EXPRESS ]   KRT15 [ SEEK ]   KRT15 [ MEM ]
Gene Expression Viewer (FireBrowse)KRT15 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3866
GTEX Portal (Tissue expression)KRT15
Human Protein AtlasENSG00000171346-KRT15 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP19012   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP19012  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP19012
Splice isoforms : SwissVarP19012
PhosPhoSitePlusP19012
Domaine pattern : Prosite (Expaxy)IF_ROD_1 (PS00226)    IF_ROD_2 (PS51842)   
Domains : Interpro (EBI)IF    Intermediate_filament_CS    Keratin_I   
Domain families : Pfam (Sanger)Filament (PF00038)   
Domain families : Pfam (NCBI)pfam00038   
Domain families : Smart (EMBL)Filament (SM01391)  
Conserved Domain (NCBI)KRT15
DMDM Disease mutations3866
Blocks (Seattle)KRT15
SuperfamilyP19012
Human Protein Atlas [tissue]ENSG00000171346-KRT15 [tissue]
Peptide AtlasP19012
HPRD01009
IPIIPI00290077   IPI00788699   IPI00797326   
Protein Interaction databases
DIP (DOE-UCLA)P19012
IntAct (EBI)P19012
FunCoupENSG00000171346
BioGRIDKRT15
STRING (EMBL)KRT15
ZODIACKRT15
Ontologies - Pathways
QuickGOP19012
Ontology : AmiGOstructural constituent of cytoskeleton  protein binding  nucleus  cytosol  intermediate filament  cytoskeleton organization  epidermis development  keratinization  extracellular exosome  cornification  scaffold protein binding  
Ontology : EGO-EBIstructural constituent of cytoskeleton  protein binding  nucleus  cytosol  intermediate filament  cytoskeleton organization  epidermis development  keratinization  extracellular exosome  cornification  scaffold protein binding  
NDEx NetworkKRT15
Atlas of Cancer Signalling NetworkKRT15
Wikipedia pathwaysKRT15
Orthology - Evolution
OrthoDB3866
GeneTree (enSembl)ENSG00000171346
Phylogenetic Trees/Animal Genes : TreeFamKRT15
HOGENOMP19012
Homologs : HomoloGeneKRT15
Homology/Alignments : Family Browser (UCSC)KRT15
Gene fusions - Rearrangements
Fusion : QuiverKRT15
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKRT15 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KRT15
dbVarKRT15
ClinVarKRT15
1000_GenomesKRT15 
Exome Variant ServerKRT15
ExAC (Exome Aggregation Consortium)ENSG00000171346
GNOMAD BrowserENSG00000171346
Varsome BrowserKRT15
Genetic variants : HAPMAP3866
Genomic Variants (DGV)KRT15 [DGVbeta]
DECIPHERKRT15 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKRT15 
Mutations
ICGC Data PortalKRT15 
TCGA Data PortalKRT15 
Broad Tumor PortalKRT15
OASIS PortalKRT15 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKRT15  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKRT15
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KRT15
DgiDB (Drug Gene Interaction Database)KRT15
DoCM (Curated mutations)KRT15 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KRT15 (select a term)
intoGenKRT15
Cancer3DKRT15(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM148030   
Orphanet
DisGeNETKRT15
MedgenKRT15
Genetic Testing Registry KRT15
NextProtP19012 [Medical]
TSGene3866
GENETestsKRT15
Target ValidationKRT15
Huge Navigator KRT15 [HugePedia]
snp3D : Map Gene to Disease3866
BioCentury BCIQKRT15
ClinGenKRT15
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3866
Chemical/Pharm GKB GenePA30208
Clinical trialKRT15
Miscellaneous
canSAR (ICR)KRT15 (select the gene name)
DataMed IndexKRT15
Probes
Litterature
PubMed45 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKRT15
EVEXKRT15
GoPubMedKRT15
iHOPKRT15
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Jun 7 18:06:14 CEST 2019
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