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KRT27 (keratin 27)

Identity

Alias_namesKRT25C
keratin 25C
keratin 27, type I
Other aliasK25IRS3
HGNC (Hugo) KRT27
LocusID (NCBI) 342574
Atlas_Id 65020
Location 17q21.2  [Link to chromosome band 17q21]
Location_base_pair Starts at 40776808 and ends at 40782534 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KRT27   30841
Cards
Entrez_Gene (NCBI)KRT27  342574  keratin 27
AliasesK25IRS3; KRT25C
GeneCards (Weizmann)KRT27
Ensembl hg19 (Hinxton)ENSG00000171446 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000171446 [Gene_View]  chr17:40776808-40782534 [Contig_View]  KRT27 [Vega]
ICGC DataPortalENSG00000171446
TCGA cBioPortalKRT27
AceView (NCBI)KRT27
Genatlas (Paris)KRT27
WikiGenes342574
SOURCE (Princeton)KRT27
Genetics Home Reference (NIH)KRT27
Genomic and cartography
GoldenPath hg38 (UCSC)KRT27  -     chr17:40776808-40782534 -  17q21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KRT27  -     17q21.2   [Description]    (hg19-Feb_2009)
EnsemblKRT27 - 17q21.2 [CytoView hg19]  KRT27 - 17q21.2 [CytoView hg38]
Mapping of homologs : NCBIKRT27 [Mapview hg19]  KRT27 [Mapview hg38]
OMIM616676   
Gene and transcription
Genbank (Entrez)AF086481 AJ564206 BC166634
RefSeq transcript (Entrez)NM_181537
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KRT27
Cluster EST : UnigeneHs.59363 [ NCBI ]
CGAP (NCI)Hs.59363
Alternative Splicing GalleryENSG00000171446
Gene ExpressionKRT27 [ NCBI-GEO ]   KRT27 [ EBI - ARRAY_EXPRESS ]   KRT27 [ SEEK ]   KRT27 [ MEM ]
Gene Expression Viewer (FireBrowse)KRT27 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)342574
GTEX Portal (Tissue expression)KRT27
Human Protein AtlasENSG00000171446-KRT27 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7Z3Y8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7Z3Y8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7Z3Y8
Splice isoforms : SwissVarQ7Z3Y8
PhosPhoSitePlusQ7Z3Y8
Domains : Interpro (EBI)IF    Keratin_I   
Domain families : Pfam (Sanger)Filament (PF00038)   
Domain families : Pfam (NCBI)pfam00038   
Domain families : Smart (EMBL)Filament (SM01391)  
Conserved Domain (NCBI)KRT27
DMDM Disease mutations342574
Blocks (Seattle)KRT27
SuperfamilyQ7Z3Y8
Human Protein Atlas [tissue]ENSG00000171446-KRT27 [tissue]
Peptide AtlasQ7Z3Y8
HPRD17244
IPIIPI00328103   
Protein Interaction databases
DIP (DOE-UCLA)Q7Z3Y8
IntAct (EBI)Q7Z3Y8
FunCoupENSG00000171446
BioGRIDKRT27
STRING (EMBL)KRT27
ZODIACKRT27
Ontologies - Pathways
QuickGOQ7Z3Y8
Ontology : AmiGOmolecular_function  structural molecule activity  cytosol  intermediate filament  biological_process  hair follicle morphogenesis  keratinization  extracellular exosome  cornification  
Ontology : EGO-EBImolecular_function  structural molecule activity  cytosol  intermediate filament  biological_process  hair follicle morphogenesis  keratinization  extracellular exosome  cornification  
NDEx NetworkKRT27
Atlas of Cancer Signalling NetworkKRT27
Wikipedia pathwaysKRT27
Orthology - Evolution
OrthoDB342574
GeneTree (enSembl)ENSG00000171446
Phylogenetic Trees/Animal Genes : TreeFamKRT27
HOVERGENQ7Z3Y8
HOGENOMQ7Z3Y8
Homologs : HomoloGeneKRT27
Homology/Alignments : Family Browser (UCSC)KRT27
Gene fusions - Rearrangements
Tumor Fusion PortalKRT27
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKRT27 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KRT27
dbVarKRT27
ClinVarKRT27
1000_GenomesKRT27 
Exome Variant ServerKRT27
ExAC (Exome Aggregation Consortium)ENSG00000171446
GNOMAD BrowserENSG00000171446
Genetic variants : HAPMAP342574
Genomic Variants (DGV)KRT27 [DGVbeta]
DECIPHERKRT27 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKRT27 
Mutations
ICGC Data PortalKRT27 
TCGA Data PortalKRT27 
Broad Tumor PortalKRT27
OASIS PortalKRT27 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKRT27  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKRT27
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KRT27
DgiDB (Drug Gene Interaction Database)KRT27
DoCM (Curated mutations)KRT27 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KRT27 (select a term)
intoGenKRT27
Cancer3DKRT27(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616676   
Orphanet
DisGeNETKRT27
MedgenKRT27
Genetic Testing Registry KRT27
NextProtQ7Z3Y8 [Medical]
TSGene342574
GENETestsKRT27
Target ValidationKRT27
Huge Navigator KRT27 [HugePedia]
snp3D : Map Gene to Disease342574
BioCentury BCIQKRT27
ClinGenKRT27
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD342574
Chemical/Pharm GKB GenePA134990976
Clinical trialKRT27
Miscellaneous
canSAR (ICR)KRT27 (select the gene name)
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKRT27
EVEXKRT27
GoPubMedKRT27
iHOPKRT27
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 13:35:34 CET 2017

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