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KRT3 (keratin 3)

Identity

Alias_nameskeratin 3
keratin 3, type II
Alias_symbol (synonym)CK3
K3
Other alias
HGNC (Hugo) KRT3
LocusID (NCBI) 3850
Atlas_Id 65022
Location 12q13.13  [Link to chromosome band 12q13]
Location_base_pair Starts at 52789685 and ends at 52796108 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KRT3   6440
Cards
Entrez_Gene (NCBI)KRT3  3850  keratin 3
AliasesCK3; K3
GeneCards (Weizmann)KRT3
Ensembl hg19 (Hinxton)ENSG00000186442 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000186442 [Gene_View]  chr12:52789685-52796108 [Contig_View]  KRT3 [Vega]
ICGC DataPortalENSG00000186442
TCGA cBioPortalKRT3
AceView (NCBI)KRT3
Genatlas (Paris)KRT3
WikiGenes3850
SOURCE (Princeton)KRT3
Genetics Home Reference (NIH)KRT3
Genomic and cartography
GoldenPath hg38 (UCSC)KRT3  -     chr12:52789685-52796108 -  12q13.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KRT3  -     12q13.13   [Description]    (hg19-Feb_2009)
EnsemblKRT3 - 12q13.13 [CytoView hg19]  KRT3 - 12q13.13 [CytoView hg38]
Mapping of homologs : NCBIKRT3 [Mapview hg19]  KRT3 [Mapview hg38]
OMIM122100   148043   
Gene and transcription
Genbank (Entrez)AJ628418 AK314987 BC156125 BC172453 BM672628
RefSeq transcript (Entrez)NM_057088
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KRT3
Cluster EST : UnigeneHs.680652 [ NCBI ]
CGAP (NCI)Hs.680652
Alternative Splicing GalleryENSG00000186442
Gene ExpressionKRT3 [ NCBI-GEO ]   KRT3 [ EBI - ARRAY_EXPRESS ]   KRT3 [ SEEK ]   KRT3 [ MEM ]
Gene Expression Viewer (FireBrowse)KRT3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3850
GTEX Portal (Tissue expression)KRT3
Protein : pattern, domain, 3D structure
UniProt/SwissProtP12035   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP12035  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP12035
Splice isoforms : SwissVarP12035
PhosPhoSitePlusP12035
Domaine pattern : Prosite (Expaxy)IF (PS00226)   
Domains : Interpro (EBI)IF    Intermediate_filament_CS    Keratin_2_head    Keratin_II   
Domain families : Pfam (Sanger)Filament (PF00038)    Keratin_2_head (PF16208)   
Domain families : Pfam (NCBI)pfam00038    pfam16208   
Domain families : Smart (EMBL)Filament (SM01391)  
Conserved Domain (NCBI)KRT3
DMDM Disease mutations3850
Blocks (Seattle)KRT3
SuperfamilyP12035
Human Protein AtlasENSG00000186442
Peptide AtlasP12035
HPRD01013
IPIIPI00290857   IPI00973210   
Protein Interaction databases
DIP (DOE-UCLA)P12035
IntAct (EBI)P12035
FunCoupENSG00000186442
BioGRIDKRT3
STRING (EMBL)KRT3
ZODIACKRT3
Ontologies - Pathways
QuickGOP12035
Ontology : AmiGOstructural molecule activity  cytosol  intermediate filament  epithelial cell differentiation  keratinization  keratin filament  intermediate filament cytoskeleton organization  extracellular exosome  cornification  
Ontology : EGO-EBIstructural molecule activity  cytosol  intermediate filament  epithelial cell differentiation  keratinization  keratin filament  intermediate filament cytoskeleton organization  extracellular exosome  cornification  
NDEx NetworkKRT3
Atlas of Cancer Signalling NetworkKRT3
Wikipedia pathwaysKRT3
Orthology - Evolution
OrthoDB3850
GeneTree (enSembl)ENSG00000186442
Phylogenetic Trees/Animal Genes : TreeFamKRT3
HOVERGENP12035
HOGENOMP12035
Homologs : HomoloGeneKRT3
Homology/Alignments : Family Browser (UCSC)KRT3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKRT3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KRT3
dbVarKRT3
ClinVarKRT3
1000_GenomesKRT3 
Exome Variant ServerKRT3
ExAC (Exome Aggregation Consortium)KRT3 (select the gene name)
Genetic variants : HAPMAP3850
Genomic Variants (DGV)KRT3 [DGVbeta]
DECIPHERKRT3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKRT3 
Mutations
ICGC Data PortalKRT3 
TCGA Data PortalKRT3 
Broad Tumor PortalKRT3
OASIS PortalKRT3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKRT3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKRT3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KRT3
DgiDB (Drug Gene Interaction Database)KRT3
DoCM (Curated mutations)KRT3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KRT3 (select a term)
intoGenKRT3
Cancer3DKRT3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM122100    148043   
Orphanet13971   
MedgenKRT3
Genetic Testing Registry KRT3
NextProtP12035 [Medical]
TSGene3850
GENETestsKRT3
Target ValidationKRT3
Huge Navigator KRT3 [HugePedia]
snp3D : Map Gene to Disease3850
BioCentury BCIQKRT3
ClinGenKRT3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3850
Chemical/Pharm GKB GenePA30228
Clinical trialKRT3
Miscellaneous
canSAR (ICR)KRT3 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKRT3
EVEXKRT3
GoPubMedKRT3
iHOPKRT3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:54:58 CEST 2017

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