Atlas of Genetics and Cytogenetics in Oncology and Haematology


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KRT4 (keratin 4)

Identity

Other namesCK-4
CK4
CYK4
K4
WSN1
HGNC (Hugo) KRT4
LocusID (NCBI) 3851
Location 12q13.13
Location_base_pair Starts at 53200327 and ends at 53207900 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

External links

Nomenclature
HGNC (Hugo)KRT4   6441
Cards
Entrez_Gene (NCBI)KRT4  3851  keratin 4
GeneCards (Weizmann)KRT4
Ensembl (Hinxton)ENSG00000170477 [Gene_View]  chr12:53200327-53207900 [Contig_View]  KRT4 [Vega]
ICGC DataPortalENSG00000170477
cBioPortalKRT4
AceView (NCBI)KRT4
Genatlas (Paris)KRT4
WikiGenes3851
SOURCE (Princeton)NM_002272
Genomic and cartography
GoldenPath (UCSC)KRT4  -  12q13.13   chr12:53200327-53207900 -  12q13.13   [Description]    (hg19-Feb_2009)
EnsemblKRT4 - 12q13.13 [CytoView]
Mapping of homologs : NCBIKRT4 [Mapview]
OMIM123940   193900   
Gene and transcription
Genbank (Entrez)AK056254 AK098110 AK296582 AK299394 AK299400
RefSeq transcript (Entrez)NM_002272
RefSeq genomic (Entrez)AC_000144 NC_000012 NC_018923 NG_007380 NT_029419 NW_001838059 NW_004929384
Consensus coding sequences : CCDS (NCBI)KRT4
Cluster EST : UnigeneHs.731814 [ NCBI ]
CGAP (NCI)Hs.731814
Alternative Splicing : Fast-db (Paris)GSHG0007496
Alternative Splicing GalleryENSG00000170477
Gene ExpressionKRT4 [ NCBI-GEO ]     KRT4 [ SEEK ]   KRT4 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP19013 (Uniprot)
NextProtP19013  [Medical]
With graphics : InterProP19013
Splice isoforms : SwissVarP19013 (Swissvar)
Domaine pattern : Prosite (Expaxy)IF (PS00226)   
Domains : Interpro (EBI)IF [organisation]   Intermediate_filament_CS [organisation]   Keratin_II [organisation]  
Related proteins : CluSTrP19013
Domain families : Pfam (Sanger)Filament (PF00038)   
Domain families : Pfam (NCBI)pfam00038   
DMDM Disease mutations3851
Blocks (Seattle)P19013
Human Protein AtlasENSG00000170477 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasP19013
HPRD00478
IPIIPI00797452   IPI01022175   IPI01021670   IPI01022327   IPI01020793   IPI00290078   
Protein Interaction databases
DIP (DOE-UCLA)P19013
IntAct (EBI)P19013
FunCoupENSG00000170477
BioGRIDKRT4
InParanoidP19013
Interologous Interaction database P19013
IntegromeDBKRT4
STRING (EMBL)KRT4
Ontologies - Pathways
Ontology : AmiGOstructural molecule activity  protein binding  nucleus  intermediate filament  cytoskeleton organization  cytoskeleton organization  cell surface  epithelial cell differentiation  keratin filament  intermediate filament cytoskeleton  negative regulation of epithelial cell proliferation  
Ontology : EGO-EBIstructural molecule activity  protein binding  nucleus  intermediate filament  cytoskeleton organization  cytoskeleton organization  cell surface  epithelial cell differentiation  keratin filament  intermediate filament cytoskeleton  negative regulation of epithelial cell proliferation  
Protein Interaction DatabaseKRT4
Wikipedia pathwaysKRT4
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)KRT4
snp3D : Map Gene to Disease3851
SNP (GeneSNP Utah)KRT4
SNP : HGBaseKRT4
Genetic variants : HAPMAPKRT4
Exome VariantKRT4
1000_GenomesKRT4 
ICGC programENSG00000170477 
Somatic Mutations in Cancer : COSMICKRT4 
CONAN: Copy Number AnalysisKRT4 
Mutations and Diseases : HGMDKRT4
Mutations and Diseases : intOGenKRT4
Genomic VariantsKRT4  KRT4 [DGVbeta]
dbVarKRT4
ClinVarKRT4
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM123940    193900   
MedgenKRT4
GENETestsKRT4
Disease Genetic AssociationKRT4
Huge Navigator KRT4 [HugePedia]  KRT4 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneKRT4
Homology/Alignments : Family Browser (UCSC)KRT4
Phylogenetic Trees/Animal Genes : TreeFamKRT4
Chemical/Protein Interactions : CTD3851
Chemical/Pharm GKB GenePA30229
Clinical trialKRT4
Cancer Resource (Charite)ENSG00000170477
Other databases
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
CoreMineKRT4
iHOPKRT4
OncoSearchKRT4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 26 16:52:16 CEST 2014

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