Atlas of Genetics and Cytogenetics in Oncology and Haematology


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KRT5 (keratin 5)

Identity

Other namesCK5
DDD
DDD1
EBS2
K5
KRT5A
HGNC (Hugo) KRT5
LocusID (NCBI) 3852
Location 12q13.13
Location_base_pair Starts at 52908359 and ends at 52914243 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)KRT5   6442
Cards
Entrez_Gene (NCBI)KRT5  3852  keratin 5
GeneCards (Weizmann)KRT5
Ensembl hg19 (Hinxton)ENSG00000186081 [Gene_View]  chr12:52908359-52914243 [Contig_View]  KRT5 [Vega]
Ensembl hg38 (Hinxton)ENSG00000186081 [Gene_View]  chr12:52908359-52914243 [Contig_View]  KRT5 [Vega]
ICGC DataPortalENSG00000186081
cBioPortalKRT5
AceView (NCBI)KRT5
Genatlas (Paris)KRT5
WikiGenes3852
SOURCE (Princeton)KRT5
Genomic and cartography
GoldenPath hg19 (UCSC)KRT5  -     chr12:52908359-52914243 -  12q13.13   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)KRT5  -     12q13.13   [Description]    (hg38-Dec_2013)
EnsemblKRT5 - 12q13.13 [CytoView hg19]  KRT5 - 12q13.13 [CytoView hg38]
Mapping of homologs : NCBIKRT5 [Mapview hg19]  KRT5 [Mapview hg38]
OMIM131760   131800   131900   131960   148040   179850   601001   609352   
Gene and transcription
Genbank (Entrez)AK093720 AK296823 AK303972 AK310827 AY373434
RefSeq transcript (Entrez)NM_000424
RefSeq genomic (Entrez)AC_000144 NC_000012 NC_018923 NG_008297 NT_029419 NW_001838059 NW_004929384
Consensus coding sequences : CCDS (NCBI)KRT5
Cluster EST : UnigeneHs.433845 [ NCBI ]
CGAP (NCI)Hs.433845
Alternative Splicing : Fast-db (Paris)GSHG0007486
Alternative Splicing GalleryENSG00000186081
Gene ExpressionKRT5 [ NCBI-GEO ]     KRT5 [ SEEK ]   KRT5 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP13647 (Uniprot)
NextProtP13647  [Medical]
With graphics : InterProP13647
Splice isoforms : SwissVarP13647 (Swissvar)
Domaine pattern : Prosite (Expaxy)IF (PS00226)   
Domains : Interpro (EBI)IF    Intermediate_filament_CS    Keratin_II   
Related proteins : CluSTrP13647
Domain families : Pfam (Sanger)Filament (PF00038)   
Domain families : Pfam (NCBI)pfam00038   
DMDM Disease mutations3852
Blocks (Seattle)P13647
PDB (SRS)3TNU   
PDB (PDBSum)3TNU   
PDB (IMB)3TNU   
PDB (RSDB)3TNU   
Human Protein AtlasENSG00000186081
Peptide AtlasP13647
HPRD01010
IPIIPI00009867   IPI00796776   IPI01023004   IPI01022815   IPI01020842   IPI01020679   IPI01021125   
Protein Interaction databases
DIP (DOE-UCLA)P13647
IntAct (EBI)P13647
FunCoupENSG00000186081
BioGRIDKRT5
IntegromeDBKRT5
STRING (EMBL)KRT5
Ontologies - Pathways
QuickGOP13647
Ontology : AmiGOstructural constituent of cytoskeleton  protein binding  nucleus  cytoplasm  mitochondrion  cytosol  intermediate filament  plasma membrane  epidermis development  membrane  hemidesmosome assembly  cell junction assembly  keratin filament  extracellular vesicular exosome  scaffold protein binding  
Ontology : EGO-EBIstructural constituent of cytoskeleton  protein binding  nucleus  cytoplasm  mitochondrion  cytosol  intermediate filament  plasma membrane  epidermis development  membrane  hemidesmosome assembly  cell junction assembly  keratin filament  extracellular vesicular exosome  scaffold protein binding  
Protein Interaction DatabaseKRT5
DoCM (Curated mutations)KRT5
Wikipedia pathwaysKRT5
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerKRT5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KRT5
dbVarKRT5
ClinVarKRT5
1000_GenomesKRT5 
Exome Variant ServerKRT5
SNP (GeneSNP Utah)KRT5
SNP : HGBaseKRT5
Genetic variants : HAPMAPKRT5
Genomic VariantsKRT5  KRT5 [DGVbeta]
Mutations
ICGC Data PortalENSG00000186081 
Somatic Mutations in Cancer : COSMICKRT5 
CONAN: Copy Number AnalysisKRT5 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Zhejiang University Center for Genetic and Genomic Medicine (ZJU-CGGM)
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)12:52908359-52914243
Mutations and Diseases : HGMDKRT5
OMIM131760    131800    131900    131960    148040    179850    601001    609352   
MedgenKRT5
NextProtP13647 [Medical]
GENETestsKRT5
Disease Genetic AssociationKRT5
Huge Navigator KRT5 [HugePedia]  KRT5 [HugeCancerGEM]
snp3D : Map Gene to Disease3852
DGIdb (Drug Gene Interaction db)KRT5
General knowledge
Homologs : HomoloGeneKRT5
Homology/Alignments : Family Browser (UCSC)KRT5
Phylogenetic Trees/Animal Genes : TreeFamKRT5
Chemical/Protein Interactions : CTD3852
Chemical/Pharm GKB GenePA30230
Clinical trialKRT5
Cancer Resource (Charite)ENSG00000186081
Other databases
Probes
Litterature
PubMed158 Pubmed reference(s) in Entrez
CoreMineKRT5
GoPubMedKRT5
iHOPKRT5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Dec 20 22:22:12 CET 2014

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