Atlas of Genetics and Cytogenetics in Oncology and Haematology


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KRT5 (keratin 5)

Identity

Other namesCK5
DDD
DDD1
EBS2
K5
KRT5A
HGNC (Hugo) KRT5
LocusID (NCBI) 3852
Location 12q13.13
Location_base_pair Starts at 52908359 and ends at 52914243 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)KRT5   6442
Cards
Entrez_Gene (NCBI)KRT5  3852  keratin 5
GeneCards (Weizmann)KRT5
Ensembl (Hinxton)ENSG00000186081 [Gene_View]  chr12:52908359-52914243 [Contig_View]  KRT5 [Vega]
ICGC DataPortalENSG00000186081
cBioPortalKRT5
AceView (NCBI)KRT5
Genatlas (Paris)KRT5
WikiGenes3852
SOURCE (Princeton)NM_000424
Genomic and cartography
GoldenPath (UCSC)KRT5  -  12q13.13   chr12:52908359-52914243 -  12q13.13   [Description]    (hg19-Feb_2009)
EnsemblKRT5 - 12q13.13 [CytoView]
Mapping of homologs : NCBIKRT5 [Mapview]
OMIM131760   131800   131900   131960   148040   179850   601001   609352   
Gene and transcription
Genbank (Entrez)AK093720 AK296823 AK303972 AK310827 AY373434
RefSeq transcript (Entrez)NM_000424
RefSeq genomic (Entrez)AC_000144 NC_000012 NC_018923 NG_008297 NT_029419 NW_001838059 NW_004929384
Consensus coding sequences : CCDS (NCBI)KRT5
Cluster EST : UnigeneHs.433845 [ NCBI ]
CGAP (NCI)Hs.433845
Alternative Splicing : Fast-db (Paris)GSHG0007486
Alternative Splicing GalleryENSG00000186081
Gene ExpressionKRT5 [ NCBI-GEO ]     KRT5 [ SEEK ]   KRT5 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP13647 (Uniprot)
NextProtP13647  [Medical]
With graphics : InterProP13647
Splice isoforms : SwissVarP13647 (Swissvar)
Domaine pattern : Prosite (Expaxy)IF (PS00226)   
Domains : Interpro (EBI)IF [organisation]   Intermediate_filament_CS [organisation]   Keratin_II [organisation]  
Related proteins : CluSTrP13647
Domain families : Pfam (Sanger)Filament (PF00038)   
Domain families : Pfam (NCBI)pfam00038   
DMDM Disease mutations3852
Blocks (Seattle)P13647
PDB (SRS)3TNU   
PDB (PDBSum)3TNU   
PDB (IMB)3TNU   
PDB (RSDB)3TNU   
Human Protein AtlasENSG00000186081 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasP13647
HPRD01010
IPIIPI00009867   IPI00796776   IPI01023004   IPI01022815   IPI01020842   IPI01020679   IPI01021125   
Protein Interaction databases
DIP (DOE-UCLA)P13647
IntAct (EBI)P13647
FunCoupENSG00000186081
BioGRIDKRT5
InParanoidP13647
Interologous Interaction database P13647
IntegromeDBKRT5
STRING (EMBL)KRT5
Ontologies - Pathways
Ontology : AmiGOstructural constituent of cytoskeleton  protein binding  nucleus  cytoplasm  mitochondrion  cytosol  intermediate filament  plasma membrane  epidermis development  membrane  hemidesmosome assembly  cell junction assembly  keratin filament  extracellular vesicular exosome  scaffold protein binding  
Ontology : EGO-EBIstructural constituent of cytoskeleton  protein binding  nucleus  cytoplasm  mitochondrion  cytosol  intermediate filament  plasma membrane  epidermis development  membrane  hemidesmosome assembly  cell junction assembly  keratin filament  extracellular vesicular exosome  scaffold protein binding  
Protein Interaction DatabaseKRT5
Wikipedia pathwaysKRT5
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)KRT5
snp3D : Map Gene to Disease3852
SNP (GeneSNP Utah)KRT5
SNP : HGBaseKRT5
Genetic variants : HAPMAPKRT5
Exome VariantKRT5
1000_GenomesKRT5 
ICGC programENSG00000186081 
Somatic Mutations in Cancer : COSMICKRT5 
CONAN: Copy Number AnalysisKRT5 
Mutations and Diseases : HGMDKRT5
Mutations and Diseases : intOGenKRT5
Genomic VariantsKRT5  KRT5 [DGVbeta]
dbVarKRT5
ClinVarKRT5
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM131760    131800    131900    131960    148040    179850    601001    609352   
MedgenKRT5
GENETestsKRT5
Disease Genetic AssociationKRT5
Huge Navigator KRT5 [HugePedia]  KRT5 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneKRT5
Homology/Alignments : Family Browser (UCSC)KRT5
Phylogenetic Trees/Animal Genes : TreeFamKRT5
Chemical/Protein Interactions : CTD3852
Chemical/Pharm GKB GenePA30230
Clinical trialKRT5
Cancer Resource (Charite)ENSG00000186081
Other databases
Probes
Litterature
PubMed158 Pubmed reference(s) in Entrez
CoreMineKRT5
iHOPKRT5
OncoSearchKRT5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 22 18:58:44 CEST 2014

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