Atlas of Genetics and Cytogenetics in Oncology and Haematology

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KRT6A (keratin 6A)

Identity

Other namesCK6A
CK6C
CK6D
K6A
K6C
K6D
KRT6C
KRT6D
PC3
HGNC (Hugo) KRT6A
LocusID (NCBI) 3853
Location 12q13.13
Location_base_pair Starts at 52880958 and ends at 52887181 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)KRT6A   6443
Cards
Entrez_Gene (NCBI)KRT6A  3853  keratin 6A
GeneCards (Weizmann)KRT6A
Ensembl hg19 (Hinxton)ENSG00000205420 [Gene_View]  chr12:52880958-52887181 [Contig_View]  KRT6A [Vega]
Ensembl hg38 (Hinxton)ENSG00000205420 [Gene_View]  chr12:52880958-52887181 [Contig_View]  KRT6A [Vega]
ICGC DataPortalENSG00000205420
cBioPortalKRT6A
AceView (NCBI)KRT6A
Genatlas (Paris)KRT6A
WikiGenes3853
SOURCE (Princeton)KRT6A
Genomic and cartography
GoldenPath hg19 (UCSC)KRT6A  -     chr12:52880958-52887181 -  12q13.13   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)KRT6A  -     12q13.13   [Description]    (hg38-Dec_2013)
EnsemblKRT6A - 12q13.13 [CytoView hg19]  KRT6A - 12q13.13 [CytoView hg38]
Mapping of homologs : NCBIKRT6A [Mapview hg19]  KRT6A [Mapview hg38]
OMIM148041   615726   
Gene and transcription
Genbank (Entrez)AK290245 AK299386 AK299428 AK301686 BC008807
RefSeq transcript (Entrez)NM_005554
RefSeq genomic (Entrez)AC_000144 NC_000012 NC_018923 NG_008298 NT_029419 NW_001838059 NW_004929384
Consensus coding sequences : CCDS (NCBI)KRT6A
Cluster EST : UnigeneHs.700779 [ NCBI ]
CGAP (NCI)Hs.700779
Alternative Splicing : Fast-db (Paris)GSHG0007485
Alternative Splicing GalleryENSG00000205420
Gene ExpressionKRT6A [ NCBI-GEO ]     KRT6A [ SEEK ]   KRT6A [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP02538 (Uniprot)
NextProtP02538  [Medical]
With graphics : InterProP02538
Splice isoforms : SwissVarP02538 (Swissvar)
Domaine pattern : Prosite (Expaxy)IF (PS00226)   
Domains : Interpro (EBI)IF    Intermediate_filament_CS    Keratin_II   
Related proteins : CluSTrP02538
Domain families : Pfam (Sanger)Filament (PF00038)   
Domain families : Pfam (NCBI)pfam00038   
DMDM Disease mutations3853
Blocks (Seattle)P02538
Human Protein AtlasENSG00000205420
Peptide AtlasP02538
HPRD01011
IPIIPI00300725   IPI00909059   IPI00942257   
Protein Interaction databases
DIP (DOE-UCLA)P02538
IntAct (EBI)P02538
FunCoupENSG00000205420
BioGRIDKRT6A
IntegromeDBKRT6A
STRING (EMBL)KRT6A
Ontologies - Pathways
QuickGOP02538
Ontology : AmiGOstructural constituent of cytoskeleton  protein binding  nucleus  positive regulation of cell proliferation  membrane  cell differentiation  keratin filament  extracellular vesicular exosome  
Ontology : EGO-EBIstructural constituent of cytoskeleton  protein binding  nucleus  positive regulation of cell proliferation  membrane  cell differentiation  keratin filament  extracellular vesicular exosome  
Protein Interaction DatabaseKRT6A
DoCM (Curated mutations)KRT6A
Wikipedia pathwaysKRT6A
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerKRT6A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KRT6A
dbVarKRT6A
ClinVarKRT6A
1000_GenomesKRT6A 
Exome Variant ServerKRT6A
SNP (GeneSNP Utah)KRT6A
SNP : HGBaseKRT6A
Genetic variants : HAPMAPKRT6A
Genomic VariantsKRT6A  KRT6A [DGVbeta]
Mutations
ICGC Data PortalENSG00000205420 
Somatic Mutations in Cancer : COSMICKRT6A 
CONAN: Copy Number AnalysisKRT6A 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)12:52880958-52887181
Mutations and Diseases : HGMDKRT6A
OMIM148041    615726   
MedgenKRT6A
NextProtP02538 [Medical]
GENETestsKRT6A
Disease Genetic AssociationKRT6A
Huge Navigator KRT6A [HugePedia]  KRT6A [HugeCancerGEM]
snp3D : Map Gene to Disease3853
DGIdb (Drug Gene Interaction db)KRT6A
General knowledge
Homologs : HomoloGeneKRT6A
Homology/Alignments : Family Browser (UCSC)KRT6A
Phylogenetic Trees/Animal Genes : TreeFamKRT6A
Chemical/Protein Interactions : CTD3853
Chemical/Pharm GKB GenePA30231
Clinical trialKRT6A
Cancer Resource (Charite)ENSG00000205420
Other databases
Probes
Litterature
PubMed47 Pubmed reference(s) in Entrez
CoreMineKRT6A
GoPubMedKRT6A
iHOPKRT6A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Dec 20 22:22:13 CET 2014
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