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KRT6B (keratin 6B)

Identity

Alias_namesKRTL1
keratin-like 1 (a type II keratin sequence)
keratin 6B, type II
Other aliasCK-6B
CK6B
K6B
PC2
PC4
HGNC (Hugo) KRT6B
LocusID (NCBI) 3854
Atlas_Id 55886
Location 12q13.13  [Link to chromosome band 12q13]
Location_base_pair Starts at 52840435 and ends at 52845910 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KRT6B   6444
Cards
Entrez_Gene (NCBI)KRT6B  3854  keratin 6B
AliasesCK-6B; CK6B; K6B; KRTL1; 
PC2; PC4
GeneCards (Weizmann)KRT6B
Ensembl hg19 (Hinxton)ENSG00000185479 [Gene_View]  chr12:52840435-52845910 [Contig_View]  KRT6B [Vega]
Ensembl hg38 (Hinxton)ENSG00000185479 [Gene_View]  chr12:52840435-52845910 [Contig_View]  KRT6B [Vega]
ICGC DataPortalENSG00000185479
TCGA cBioPortalKRT6B
AceView (NCBI)KRT6B
Genatlas (Paris)KRT6B
WikiGenes3854
SOURCE (Princeton)KRT6B
Genetics Home Reference (NIH)KRT6B
Genomic and cartography
GoldenPath hg19 (UCSC)KRT6B  -     chr12:52840435-52845910 -  12q13.13   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)KRT6B  -     12q13.13   [Description]    (hg38-Dec_2013)
EnsemblKRT6B - 12q13.13 [CytoView hg19]  KRT6B - 12q13.13 [CytoView hg38]
Mapping of homologs : NCBIKRT6B [Mapview hg19]  KRT6B [Mapview hg38]
OMIM148042   615728   
Gene and transcription
Genbank (Entrez)AK296729 BC034535 BG679927 DQ891327 DQ894511
RefSeq transcript (Entrez)NM_005555
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KRT6B
Cluster EST : UnigeneHs.708950 [ NCBI ]
CGAP (NCI)Hs.708950
Alternative Splicing GalleryENSG00000185479
Gene ExpressionKRT6B [ NCBI-GEO ]   KRT6B [ EBI - ARRAY_EXPRESS ]   KRT6B [ SEEK ]   KRT6B [ MEM ]
Gene Expression Viewer (FireBrowse)KRT6B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3854
GTEX Portal (Tissue expression)KRT6B
Protein : pattern, domain, 3D structure
UniProt/SwissProtP04259   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP04259  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP04259
Splice isoforms : SwissVarP04259
PhosPhoSitePlusP04259
Domaine pattern : Prosite (Expaxy)IF (PS00226)   
Domains : Interpro (EBI)IF    Intermediate_filament_CS    Keratin_2_head    Keratin_II   
Domain families : Pfam (Sanger)Filament (PF00038)    Keratin_2_head (PF16208)   
Domain families : Pfam (NCBI)pfam00038    pfam16208   
Domain families : Smart (EMBL)Filament (SM01391)  
Conserved Domain (NCBI)KRT6B
DMDM Disease mutations3854
Blocks (Seattle)KRT6B
SuperfamilyP04259
Human Protein AtlasENSG00000185479
Peptide AtlasP04259
HPRD01012
IPIIPI00293665   IPI00910738   
Protein Interaction databases
DIP (DOE-UCLA)P04259
IntAct (EBI)P04259
FunCoupENSG00000185479
BioGRIDKRT6B
STRING (EMBL)KRT6B
ZODIACKRT6B
Ontologies - Pathways
QuickGOP04259
Ontology : AmiGOstructural constituent of cytoskeleton  protein binding  cytoskeleton organization  ectoderm development  keratin filament  extracellular exosome  
Ontology : EGO-EBIstructural constituent of cytoskeleton  protein binding  cytoskeleton organization  ectoderm development  keratin filament  extracellular exosome  
NDEx NetworkKRT6B
Atlas of Cancer Signalling NetworkKRT6B
Wikipedia pathwaysKRT6B
Orthology - Evolution
OrthoDB3854
GeneTree (enSembl)ENSG00000185479
Phylogenetic Trees/Animal Genes : TreeFamKRT6B
HOVERGENP04259
HOGENOMP04259
Homologs : HomoloGeneKRT6B
Homology/Alignments : Family Browser (UCSC)KRT6B
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKRT6B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KRT6B
dbVarKRT6B
ClinVarKRT6B
1000_GenomesKRT6B 
Exome Variant ServerKRT6B
ExAC (Exome Aggregation Consortium)KRT6B (select the gene name)
Genetic variants : HAPMAP3854
Genomic Variants (DGV)KRT6B [DGVbeta]
DECIPHER (Syndromes)12:52840435-52845910  ENSG00000185479
CONAN: Copy Number AnalysisKRT6B 
Mutations
ICGC Data PortalKRT6B 
TCGA Data PortalKRT6B 
Broad Tumor PortalKRT6B
OASIS PortalKRT6B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKRT6B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKRT6B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KRT6B
DgiDB (Drug Gene Interaction Database)KRT6B
DoCM (Curated mutations)KRT6B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KRT6B (select a term)
intoGenKRT6B
Cancer3DKRT6B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM148042    615728   
Orphanet2169   
MedgenKRT6B
Genetic Testing Registry KRT6B
NextProtP04259 [Medical]
TSGene3854
GENETestsKRT6B
Huge Navigator KRT6B [HugePedia]
snp3D : Map Gene to Disease3854
BioCentury BCIQKRT6B
ClinGenKRT6B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3854
Chemical/Pharm GKB GenePA30232
Clinical trialKRT6B
Miscellaneous
canSAR (ICR)KRT6B (select the gene name)
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKRT6B
EVEXKRT6B
GoPubMedKRT6B
iHOPKRT6B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:12:18 CET 2017

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