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KRT6C (keratin 6C)

Identity

Alias_namesKRT6E
keratin 6E
keratin 6C, type II
Other aliasK6E
PPKNEFD
HGNC (Hugo) KRT6C
LocusID (NCBI) 286887
Atlas_Id 65035
Location 12q13.13  [Link to chromosome band 12q13]
Location_base_pair Starts at 52468516 and ends at 52473785 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KRT6C   20406
Cards
Entrez_Gene (NCBI)KRT6C  286887  keratin 6C
AliasesK6E; KRT6E; PPKNEFD
GeneCards (Weizmann)KRT6C
Ensembl hg19 (Hinxton)ENSG00000170465 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000170465 [Gene_View]  chr12:52468516-52473785 [Contig_View]  KRT6C [Vega]
ICGC DataPortalENSG00000170465
TCGA cBioPortalKRT6C
AceView (NCBI)KRT6C
Genatlas (Paris)KRT6C
WikiGenes286887
SOURCE (Princeton)KRT6C
Genetics Home Reference (NIH)KRT6C
Genomic and cartography
GoldenPath hg38 (UCSC)KRT6C  -     chr12:52468516-52473785 -  12q13.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KRT6C  -     12q13.13   [Description]    (hg19-Feb_2009)
EnsemblKRT6C - 12q13.13 [CytoView hg19]  KRT6C - 12q13.13 [CytoView hg38]
Mapping of homologs : NCBIKRT6C [Mapview hg19]  KRT6C [Mapview hg38]
OMIM612315   615735   
Gene and transcription
Genbank (Entrez)AK299478 AK313239 BC110639 BC130583 BC130585
RefSeq transcript (Entrez)NM_173086
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KRT6C
Cluster EST : UnigeneHs.709234 [ NCBI ]
CGAP (NCI)Hs.709234
Alternative Splicing GalleryENSG00000170465
Gene ExpressionKRT6C [ NCBI-GEO ]   KRT6C [ EBI - ARRAY_EXPRESS ]   KRT6C [ SEEK ]   KRT6C [ MEM ]
Gene Expression Viewer (FireBrowse)KRT6C [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)286887
GTEX Portal (Tissue expression)KRT6C
Protein : pattern, domain, 3D structure
UniProt/SwissProtP48668   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP48668  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP48668
Splice isoforms : SwissVarP48668
PhosPhoSitePlusP48668
Domaine pattern : Prosite (Expaxy)IF (PS00226)   
Domains : Interpro (EBI)IF    Intermediate_filament_CS    Keratin_2_head    Keratin_II   
Domain families : Pfam (Sanger)Filament (PF00038)    Keratin_2_head (PF16208)   
Domain families : Pfam (NCBI)pfam00038    pfam16208   
Domain families : Smart (EMBL)Filament (SM01391)  
Conserved Domain (NCBI)KRT6C
DMDM Disease mutations286887
Blocks (Seattle)KRT6C
SuperfamilyP48668
Human Protein AtlasENSG00000170465
Peptide AtlasP48668
HPRD17247
IPIIPI00299145   IPI00930073   IPI00956313   
Protein Interaction databases
DIP (DOE-UCLA)P48668
IntAct (EBI)P48668
FunCoupENSG00000170465
BioGRIDKRT6C
STRING (EMBL)KRT6C
ZODIACKRT6C
Ontologies - Pathways
QuickGOP48668
Ontology : AmiGOstructural molecule activity  protein binding  cytosol  intermediate filament  keratinization  keratin filament  intermediate filament cytoskeleton organization  extracellular exosome  cornification  
Ontology : EGO-EBIstructural molecule activity  protein binding  cytosol  intermediate filament  keratinization  keratin filament  intermediate filament cytoskeleton organization  extracellular exosome  cornification  
NDEx NetworkKRT6C
Atlas of Cancer Signalling NetworkKRT6C
Wikipedia pathwaysKRT6C
Orthology - Evolution
OrthoDB286887
GeneTree (enSembl)ENSG00000170465
Phylogenetic Trees/Animal Genes : TreeFamKRT6C
HOVERGENP48668
HOGENOMP48668
Homologs : HomoloGeneKRT6C
Homology/Alignments : Family Browser (UCSC)KRT6C
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKRT6C [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KRT6C
dbVarKRT6C
ClinVarKRT6C
1000_GenomesKRT6C 
Exome Variant ServerKRT6C
ExAC (Exome Aggregation Consortium)KRT6C (select the gene name)
Genetic variants : HAPMAP286887
Genomic Variants (DGV)KRT6C [DGVbeta]
DECIPHERKRT6C [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKRT6C 
Mutations
ICGC Data PortalKRT6C 
TCGA Data PortalKRT6C 
Broad Tumor PortalKRT6C
OASIS PortalKRT6C [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKRT6C  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKRT6C
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KRT6C
DgiDB (Drug Gene Interaction Database)KRT6C
DoCM (Curated mutations)KRT6C (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KRT6C (select a term)
intoGenKRT6C
Cancer3DKRT6C(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612315    615735   
Orphanet22866   
MedgenKRT6C
Genetic Testing Registry KRT6C
NextProtP48668 [Medical]
TSGene286887
GENETestsKRT6C
Target ValidationKRT6C
Huge Navigator KRT6C [HugePedia]
snp3D : Map Gene to Disease286887
BioCentury BCIQKRT6C
ClinGenKRT6C
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD286887
Chemical/Pharm GKB GenePA134891227
Clinical trialKRT6C
Miscellaneous
canSAR (ICR)KRT6C (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKRT6C
EVEXKRT6C
GoPubMedKRT6C
iHOPKRT6C
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:12:10 CEST 2017

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